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Mechanism of Action

Mechanism of Action of Phenytoin

June 3, 2025 by Harsh Singh Rajput
Phenytoin MOA – voltage-gated sodium channel blocker

Introduction Phenytoin is one of the oldest and most widely used antiepileptic drugs (AEDs), primarily for treating focal … Read more

Mechanism of Action of Levetiracetam

June 3, 2025 by Harsh Singh Rajput
Levetiracetam MOA – SV2A modulation in epilepsy

Introduction Levetiracetam is a novel, broad-spectrum antiepileptic drug (AED) used in the treatment of partial seizures, myoclonic seizures, … Read more

Mechanism of Action of Lamotrigine

June 3, 2025 by Harsh Singh Rajput
Lamotrigine MOA – sodium channel blocker and glutamate inhibitor

Introduction Lamotrigine is a broad-spectrum antiepileptic drug (AED) and an effective mood stabilizer, especially in bipolar depression. It … Read more

Mechanism of Action of Carbamazepine

June 3, 2025 by Harsh Singh Rajput
Carbamazepine mechanism of action – sodium channel blocker in epilepsy and neuralgia

Introduction Carbamazepine is a classic antiepileptic drug (AED) and mood stabilizer. It is mainly used to treat partial … Read more

Mechanism of Action of Valproate (Mood Stabilizer & Antiepileptic)

June 3, 2025 by Harsh Singh Rajput
Valproate mechanism of action – GABA elevation and ion channel blockade

Introduction Valproate (also known as valproic acid or divalproex sodium) is a widely used mood stabilizer and broad-spectrum … Read more

Mechanism of Action of Lithium (Mood Stabilizer)

June 3, 2025 by Harsh Singh Rajput
Lithium mechanism of action – mood stabilization via inositol pathway inhibition

Introduction Lithium is the gold-standard mood stabilizer, used for managing bipolar disorder, especially to control acute manic episodes … Read more

Mechanism of Action of Typical Antipsychotics (First-Generation)

June 3, 2025 by Harsh Singh Rajput
Typical antipsychotics MOA – D2 receptor antagonism in mesolimbic pathway

Introduction Typical antipsychotics, also known as first-generation antipsychotics (FGAs), are primarily used to treat schizophrenia, acute psychosis, and … Read more

Mechanism of Action of Benzodiazepines

June 3, 2025 by Harsh Singh Rajput
Benzodiazepines mechanism – GABA-A receptor binding and CNS depression

Introduction Benzodiazepines are a class of psychoactive drugs widely used for their anxiolytic, sedative, hypnotic, anticonvulsant, and muscle … Read more

Mechanism of Action of Tricyclic Antidepressants (TCAs)

May 31, 2025 by Harsh Singh Rajput
TCA mechanism – serotonin and norepinephrine reuptake inhibition with receptor blockade

Introduction Tricyclic antidepressants (TCAs) are one of the oldest classes of antidepressant medications. Although largely replaced by SSRIs … Read more

Mechanism of Action of Alpha-Glucosidase Inhibitors

May 31, 2025 by Harsh Singh Rajput
Alpha-glucosidase inhibitors mechanism – delayed carbohydrate digestion at intestinal brush border

Introduction Alpha-glucosidase inhibitors are oral antidiabetic agents that reduce postprandial hyperglycemia by delaying carbohydrate digestion and glucose absorption … Read more

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