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Mechanism of Action

Mechanism of Action of Aminoglycosides

July 4, 2025June 20, 2025 by Harsh Singh Rajput
Aminoglycoside MOA – 30S ribosomal subunit binding and mRNA misreading

Introduction Aminoglycosides are potent bactericidal antibiotics used mainly against aerobic Gram-negative bacilli and serious systemic infections. Common examples … Read more

Mechanism of Action of Macrolides (Protein Synthesis Inhibitor Antibiotics)

June 23, 2025June 20, 2025 by Harsh Singh Rajput
Macrolide MOA – 50S ribosome binding and protein synthesis inhibition

Introduction Macrolides are a widely used class of bacteriostatic antibiotics that inhibit bacterial protein synthesis. They are especially … Read more

Mechanism of Action of Cephalosporins (β-Lactam Antibiotics)

June 23, 2025June 19, 2025 by Harsh Singh Rajput
Cephalosporin MOA – PBP inhibition and bacterial cell wall lysis

Introduction Cephalosporins are a large group of β-lactam antibiotics, structurally and functionally similar to penicillins. They are classified … Read more

Mechanism of Action of Penicillins (β-lactam Antibiotics)

June 23, 2025June 19, 2025 by Harsh Singh Rajput
Penicillins MOA – Cell wall synthesis inhibition

Introduction Penicillins are one of the oldest and most widely used classes of antibiotics, belonging to the β-lactam … Read more

Mechanism of Action of Lacosamide (Newer Antiepileptic Drug)

June 23, 2025June 18, 2025 by Harsh Singh Rajput
Lacosamide MOA – Enhances slow inactivation of sodium channels in epilepsy

Introduction Lacosamide is a newer-generation antiepileptic drug (AED) used for the treatment of focal (partial) seizures and adjunctive … Read more

Mechanism of Action of Gabapentin

July 4, 2025June 3, 2025 by Harsh Singh Rajput
Gabapentin MOA – calcium channel modulator in epilepsy and neuropathic pain

Introduction Gabapentin is an antiepileptic drug and one of the most widely prescribed medications for neuropathic pain, postherpetic … Read more

Mechanism of Action of Ethosuximide

June 3, 2025 by Harsh Singh Rajput
Ethosuximide MOA – T-type calcium channel blocker for absence seizures

Introduction Ethosuximide is the first-line drug for treating absence seizures, a type of generalized seizure common in children. … Read more

Mechanism of Action of Topiramate

June 3, 2025 by Harsh Singh Rajput
Topiramate MOA – GABA enhancer, AMPA blocker, sodium channel inhibitor

Introduction Topiramate is a broad-spectrum antiepileptic drug (AED) known for its use in treating partial and generalized seizures, … Read more

Mechanism of Action of Phenytoin

June 3, 2025 by Harsh Singh Rajput
Phenytoin MOA – voltage-gated sodium channel blocker

Introduction Phenytoin is one of the oldest and most widely used antiepileptic drugs (AEDs), primarily for treating focal … Read more

Mechanism of Action of Levetiracetam

June 3, 2025 by Harsh Singh Rajput
Levetiracetam MOA – SV2A modulation in epilepsy

Introduction Levetiracetam is a novel, broad-spectrum antiepileptic drug (AED) used in the treatment of partial seizures, myoclonic seizures, … Read more

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