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USMLE Pharmacology

Mechanism of Action of Jardiance (Empagliflozin)

July 3, 2025 by Harsh Singh Rajput
Mechanism of action of Jardiance

Introduction Jardiance (empagliflozin) is a sodium–glucose co-transporter 2 (SGLT2) inhibitor used for type 2 diabetes mellitus (T2DM), heart failure … Read more

Mechanism of Action of Wellbutrin (Bupropion)

July 2, 2025 by Harsh Singh Rajput
Mechanism of action of Wellbutrin

Introduction Wellbutrin (bupropion) is an atypical antidepressant and smoking cessation aid. It primarily works by inhibiting reuptake of … Read more

Mechanism of Action of Januvia (Sitagliptin)

July 2, 2025 by Harsh Singh Rajput
Mechanism of action of Januvia

Introduction Januvia (sitagliptin) is an oral dipeptidyl peptidase‑4 (DPP‑4) inhibitor used to improve glycemic control in type 2 diabetes … Read more

Mechanism of Action of Anakinra

July 2, 2025 by Harsh Singh Rajput
Mechanism of action of Anakinra

Introduction Anakinra is a recombinant human interleukin‑1 receptor antagonist (IL‑1Ra) used to treat rheumatoid arthritis, neonatal-onset multisystem inflammatory … Read more

Mechanism of Action of Farxiga (Dapagliflozin)

July 1, 2025 by Harsh Singh Rajput
Mechanism of action Farxiga

Introduction Dapagliflozin (trade name Farxiga) is a sodium–glucose co‑transporter 2 (SGLT2) inhibitor used in type 2 diabetes mellitus (T2DM) and … Read more

Mechanism of Action of Bupropion

July 1, 2025 by Harsh Singh Rajput
Bupropion Mechanism of Action

Introduction Bupropion is an atypical antidepressant primarily used to treat major depressive disorder, seasonal affective disorder, and as … Read more

Mechanism of Action of Lokelma (Sodium Zirconium Cyclosilicate)

July 4, 2025July 1, 2025 by Harsh Singh Rajput
Lokelma Mechanism of Action

Introduction Lokelma is an oral, non-absorbed potassium binder used to treat hyperkalemia. It works by selectively trapping potassium … Read more

Mechanism of Action of Finerenone (Kerendia)

July 4, 2025July 1, 2025 by Harsh Singh Rajput
Finerenone Mechanism of Action

Introduction Finerenone is a nonsteroidal, selective mineralocorticoid receptor antagonist (MRA) approved for reducing the risk of cardiovascular and … Read more

Mechanism of Action of Mounjaro (Tirzepatide)

July 1, 2025 by Harsh Singh Rajput
Mounjaro Mechanism of Action

Introduction Tirzepatide, marketed as Mounjaro for type 2 diabetes and Zepbound for obesity, is a dual GIP/GLP‑1 receptor … Read more

Mechanism of Action of Entresto (Sacubitril/Valsartan)

July 1, 2025 by Harsh Singh Rajput
Mechanism of Action

Introduction Entresto is a combination drug containing sacubitril, a neprilysin inhibitor, and valsartan, an angiotensin II receptor blocker … Read more

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