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Mechanism of Action of Clonidine (Centrally Acting Antihypertensive)

June 24, 2025 by Harsh Singh Rajput
Clonidine MOA – Central α2 Agonist Reducing Sympathetic Outflow

Introduction Clonidine is a centrally acting α2-adrenergic receptor agonist used primarily for hypertension, but also for opioid withdrawal, … Read more

Mechanism of Action of Atropine (Muscarinic Antagonist)

June 24, 2025 by Harsh Singh Rajput
Atropine MOA – Competitive Muscarinic Receptor Antagonist

Introduction Atropine is a classic anticholinergic drug that works by competitively inhibiting muscarinic acetylcholine receptors (mAChRs). It is … Read more

Mechanism of Action of Amiodarone (Class III Antiarrhythmic)

June 23, 2025 by Harsh Singh Rajput
Amiodarone MOA – Multi-class antiarrhythmic with K⁺ channel blockade

Introduction Amiodarone is a powerful Class III antiarrhythmic agent used to treat various life-threatening cardiac arrhythmias, including ventricular … Read more

Mechanism of Action of Colchicine (Anti-inflammatory in Gout)

June 23, 2025 by Harsh Singh Rajput
Colchicine MOA – Inhibition of microtubule polymerization in neutrophils

Introduction Colchicine is an anti-inflammatory drug primarily used in the management of acute gouty arthritis, familial Mediterranean fever, … Read more

Mechanism of Action of Gabapentin

June 3, 2025 by Harsh Singh Rajput
Gabapentin MOA – calcium channel modulator in epilepsy and neuropathic pain

Introduction Gabapentin is an antiepileptic drug and one of the most widely prescribed medications for neuropathic pain, postherpetic … Read more

Mechanism of Action of Ethosuximide

June 3, 2025 by Harsh Singh Rajput
Ethosuximide MOA – T-type calcium channel blocker for absence seizures

Introduction Ethosuximide is the first-line drug for treating absence seizures, a type of generalized seizure common in children. … Read more

Mechanism of Action of Topiramate

June 3, 2025 by Harsh Singh Rajput
Topiramate MOA – GABA enhancer, AMPA blocker, sodium channel inhibitor

Introduction Topiramate is a broad-spectrum antiepileptic drug (AED) known for its use in treating partial and generalized seizures, … Read more

Mechanism of Action of Phenytoin

June 3, 2025 by Harsh Singh Rajput
Phenytoin MOA – voltage-gated sodium channel blocker

Introduction Phenytoin is one of the oldest and most widely used antiepileptic drugs (AEDs), primarily for treating focal … Read more

Mechanism of Action of Levetiracetam

June 3, 2025 by Harsh Singh Rajput
Levetiracetam MOA – SV2A modulation in epilepsy

Introduction Levetiracetam is a novel, broad-spectrum antiepileptic drug (AED) used in the treatment of partial seizures, myoclonic seizures, … Read more

Mechanism of Action of Lamotrigine

June 3, 2025 by Harsh Singh Rajput
Lamotrigine MOA – sodium channel blocker and glutamate inhibitor

Introduction Lamotrigine is a broad-spectrum antiepileptic drug (AED) and an effective mood stabilizer, especially in bipolar depression. It … Read more

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