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Mechanism of Action of Valproate (Mood Stabilizer & Antiepileptic)

June 3, 2025 by Harsh Singh Rajput
Valproate mechanism of action – GABA elevation and ion channel blockade

Introduction Valproate (also known as valproic acid or divalproex sodium) is a widely used mood stabilizer and broad-spectrum … Read more

Mechanism of Action of Lithium (Mood Stabilizer)

June 3, 2025 by Harsh Singh Rajput
Lithium mechanism of action – mood stabilization via inositol pathway inhibition

Introduction Lithium is the gold-standard mood stabilizer, used for managing bipolar disorder, especially to control acute manic episodes … Read more

Mechanism of Action of Atypical Antipsychotics (Second-Generation)

July 4, 2025June 3, 2025 by Harsh Singh Rajput
Atypical antipsychotics MOA – D2 and 5-HT2A receptor action in schizophrenia

Introduction Atypical antipsychotics, also known as second-generation antipsychotics (SGAs), are widely used in the treatment of schizophrenia, bipolar … Read more

Mechanism of Action of Typical Antipsychotics (First-Generation)

June 3, 2025 by Harsh Singh Rajput
Typical antipsychotics MOA – D2 receptor antagonism in mesolimbic pathway

Introduction Typical antipsychotics, also known as first-generation antipsychotics (FGAs), are primarily used to treat schizophrenia, acute psychosis, and … Read more

Mechanism of Action of Tricyclic Antidepressants (TCAs)

May 31, 2025 by Harsh Singh Rajput
TCA mechanism – serotonin and norepinephrine reuptake inhibition with receptor blockade

Introduction Tricyclic antidepressants (TCAs) are one of the oldest classes of antidepressant medications. Although largely replaced by SSRIs … Read more

Mechanism of Action of SSRIs (Selective Serotonin Reuptake Inhibitors)

July 4, 2025May 31, 2025 by Harsh Singh Rajput
SSRIs mechanism – serotonin reuptake inhibition in synaptic cleft

Mechanism of Action of SSRIs (Selective Serotonin Reuptake Inhibitors) Introduction Selective Serotonin Reuptake Inhibitors (SSRIs) are first-line antidepressants … Read more

Mechanism of Action of Alpha-Glucosidase Inhibitors

May 31, 2025 by Harsh Singh Rajput
Alpha-glucosidase inhibitors mechanism – delayed carbohydrate digestion at intestinal brush border

Introduction Alpha-glucosidase inhibitors are oral antidiabetic agents that reduce postprandial hyperglycemia by delaying carbohydrate digestion and glucose absorption … Read more

Mechanism of Action of DPP-4 Inhibitors

May 31, 2025 by Harsh Singh Rajput
DPP-4 inhibitors mechanism – incretin hormone enhancement via enzyme blockade

Introduction Dipeptidyl Peptidase-4 (DPP-4) Inhibitors, commonly referred to as gliptins, are oral antidiabetic drugs that enhance the action … Read more

Mechanism of Action of Thiazide Diuretics

May 30, 2025 by Harsh Singh Rajput
Thiazide diuretics mechanism – inhibition of sodium chloride symporter in the distal tubule

Introduction Thiazide diuretics are one of the most commonly prescribed classes of antihypertensive agents, especially in the U.S. … Read more

Amoxicillin – Mechanism of Action

May 27, 2025 by Harsh Singh Rajput
Amoxicillin mechanism of action – inhibition of bacterial cell wall synthesis via PBPs

Introduction Amoxicillin is a widely used broad-spectrum penicillin antibiotic belonging to the β-lactam class. It is effective against … Read more

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