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Mechanism of Action of Proton Pump Inhibitors (PPIs)

June 23, 2025 by Harsh Singh Rajput
Proton Pump Inhibitor MOA – H⁺/K⁺ ATPase Inhibition

Introduction Proton Pump Inhibitors (PPIs) are potent acid-suppressing drugs widely used in the treatment of gastric and duodenal … Read more

Mechanism of Action of Benzodiazepines (CNS Depressants)

June 23, 2025June 23, 2025 by Harsh Singh Rajput
Benzodiazepine MOA – GABA-A receptor binding and chloride channel modulation

Introduction Benzodiazepines are a widely used class of central nervous system (CNS) depressants known for their anxiolytic, sedative, … Read more

Mechanism of Action of Metronidazole (DNA-Damaging Antibiotic)

June 23, 2025June 22, 2025 by Harsh Singh Rajput
Metronidazole MOA – DNA damage via nitro radical formation

Introduction Metronidazole is a unique antibiotic and antiprotozoal agent that exerts its action by damaging DNA in anaerobic … Read more

Mechanism of Action of Linezolid (Oxazolidinone Antibiotics)

June 23, 2025June 22, 2025 by Harsh Singh Rajput
Linezolid MOA – 50S ribosomal subunit and initiation inhibition

Introduction Linezolid is a synthetic bacteriostatic antibiotic belonging to the oxazolidinone class. It is primarily active against Gram-positive … Read more

Mechanism of Action of Sulfonamides (Folic Acid Synthesis Inhibitors)

June 23, 2025June 21, 2025 by Harsh Singh Rajput
Sulfonamide MOA – Folic acid synthesis inhibition via dihydropteroate synthase

Introduction Sulfonamides are synthetic bacteriostatic antibiotics that inhibit folic acid synthesis in bacteria. Because mammals obtain folate from … Read more

Mechanism of Action of Glycopeptides (e.g., Vancomycin)

June 23, 2025June 21, 2025 by Harsh Singh Rajput
Vancomycin MOA – D-Ala-D-Ala binding and peptidoglycan inhibition

Introduction Glycopeptides, most notably vancomycin, are a class of bactericidal antibiotics that inhibit bacterial cell wall synthesis by … Read more

Mechanism of Action of Aminoglycosides

July 4, 2025June 20, 2025 by Harsh Singh Rajput
Aminoglycoside MOA – 30S ribosomal subunit binding and mRNA misreading

Introduction Aminoglycosides are potent bactericidal antibiotics used mainly against aerobic Gram-negative bacilli and serious systemic infections. Common examples … Read more

Mechanism of Action of Levetiracetam

June 3, 2025 by Harsh Singh Rajput
Levetiracetam MOA – SV2A modulation in epilepsy

Introduction Levetiracetam is a novel, broad-spectrum antiepileptic drug (AED) used in the treatment of partial seizures, myoclonic seizures, … Read more

Mechanism of Action of Lamotrigine

June 3, 2025 by Harsh Singh Rajput
Lamotrigine MOA – sodium channel blocker and glutamate inhibitor

Introduction Lamotrigine is a broad-spectrum antiepileptic drug (AED) and an effective mood stabilizer, especially in bipolar depression. It … Read more

Mechanism of Action of Carbamazepine

June 3, 2025 by Harsh Singh Rajput
Carbamazepine mechanism of action – sodium channel blocker in epilepsy and neuralgia

Introduction Carbamazepine is a classic antiepileptic drug (AED) and mood stabilizer. It is mainly used to treat partial … Read more

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