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Mechanism of Action of Lamotrigine

June 3, 2025 by Harsh Singh Rajput
Lamotrigine MOA – sodium channel blocker and glutamate inhibitor

Introduction Lamotrigine is a broad-spectrum antiepileptic drug (AED) and an effective mood stabilizer, especially in bipolar depression. It … Read more

Mechanism of Action of Carbamazepine

June 3, 2025 by Harsh Singh Rajput
Carbamazepine mechanism of action – sodium channel blocker in epilepsy and neuralgia

Introduction Carbamazepine is a classic antiepileptic drug (AED) and mood stabilizer. It is mainly used to treat partial … Read more

Mechanism of Action of Atypical Antipsychotics (Second-Generation)

July 4, 2025June 3, 2025 by Harsh Singh Rajput
Atypical antipsychotics MOA – D2 and 5-HT2A receptor action in schizophrenia

Introduction Atypical antipsychotics, also known as second-generation antipsychotics (SGAs), are widely used in the treatment of schizophrenia, bipolar … Read more

Mechanism of Action of Typical Antipsychotics (First-Generation)

June 3, 2025 by Harsh Singh Rajput
Typical antipsychotics MOA – D2 receptor antagonism in mesolimbic pathway

Introduction Typical antipsychotics, also known as first-generation antipsychotics (FGAs), are primarily used to treat schizophrenia, acute psychosis, and … Read more

Mechanism of Action of Tricyclic Antidepressants (TCAs)

May 31, 2025 by Harsh Singh Rajput
TCA mechanism – serotonin and norepinephrine reuptake inhibition with receptor blockade

Introduction Tricyclic antidepressants (TCAs) are one of the oldest classes of antidepressant medications. Although largely replaced by SSRIs … Read more

Mechanism of Action of SSRIs (Selective Serotonin Reuptake Inhibitors)

July 4, 2025May 31, 2025 by Harsh Singh Rajput
SSRIs mechanism – serotonin reuptake inhibition in synaptic cleft

Mechanism of Action of SSRIs (Selective Serotonin Reuptake Inhibitors) Introduction Selective Serotonin Reuptake Inhibitors (SSRIs) are first-line antidepressants … Read more

Mechanism of Action of Alpha-Glucosidase Inhibitors

May 31, 2025 by Harsh Singh Rajput
Alpha-glucosidase inhibitors mechanism – delayed carbohydrate digestion at intestinal brush border

Introduction Alpha-glucosidase inhibitors are oral antidiabetic agents that reduce postprandial hyperglycemia by delaying carbohydrate digestion and glucose absorption … Read more

Mechanism of Action of Thiazolidinediones

May 31, 2025 by Harsh Singh Rajput
TZD mechanism – PPAR gamma activation and insulin sensitivity improvement

Introduction Thiazolidinediones (TZDs), also known as glitazones, are oral antidiabetic drugs used to improve insulin sensitivity in patients … Read more

Mechanism of Action of Meglitinides

July 4, 2025May 31, 2025 by Harsh Singh Rajput
Meglitinides mechanism – insulin secretion by SUR1-mediated KATP channel blockade

Introduction Meglitinides, also known as glinides, are short-acting insulin secretagogues used in the treatment of type 2 diabetes … Read more

Mechanism of Action of Sulfonylureas

May 31, 2025 by Harsh Singh Rajput
Sulfonylureas mechanism – insulin secretion via KATP channel inhibition

Introduction Sulfonylureas are one of the oldest and most widely used classes of oral antidiabetic agents. They are … Read more

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