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Harsh Singh Rajput

I am pursuing MBA in pharmaceutical management from NIPER Hyderabad with a strong academic record and proven success in national-level pharmacy entrance exams. I secured AIR 61 in NIPER 2024 (MS/M.Pharm) and AIR 27 in NIPER MBA, along with AIR 147 in GPAT 2024 and AIR 907 in GPAT 2023. I also achieved AIR 6 in AIIMS CRE-2025 for Drug Store Keeper and was selected as a Pharmacist (AIR 61) for ESIC. Additionally, I was the Runner-Up in Round 2 of the EY Case Study Competition. At PharmacyFreak.com, I aim to guide future pharmacists through expert content, exam strategies, and insightful resources based on real experience and academic excellence. Mail- harsh@pharmacyfreak.com

Mechanism of Action of Thiazide Diuretics

May 30, 2025 by Harsh Singh Rajput
Thiazide diuretics mechanism – inhibition of sodium chloride symporter in the distal tubule

Introduction Thiazide diuretics are one of the most commonly prescribed classes of antihypertensive agents, especially in the U.S. … Read more

Mechanism of Action of Beta-Blockers

May 30, 2025May 30, 2025 by Harsh Singh Rajput
Beta-blockers mechanism of action – antagonism of beta-adrenergic receptors reducing heart rate and contractility

Introduction Beta-blockers are a widely used class of drugs in cardiovascular medicine. They block the effects of catecholamines, … Read more

Mechanism of Action of Calcium Channel Blockers (CCBs)

May 27, 2025 by Harsh Singh Rajput
Calcium channel blockers mechanism – L-type calcium channel inhibition and vasodilation

Introduction Calcium Channel Blockers (CCBs) are a major class of antihypertensive and anti-anginal medications. They work by blocking … Read more

Mechanism of Action of Angiotensin II Receptor Blockers (ARBs)

May 27, 2025 by Harsh Singh Rajput
Angiotensin II receptor blockers mechanism – inhibition of AT1-mediated vasoconstriction

Introduction Angiotensin II Receptor Blockers (ARBs) are a major class of antihypertensive drugs. They selectively block the angiotensin … Read more

ACE Inhibitors – Mechanism of Action

May 27, 2025 by Harsh Singh Rajput
: ACE inhibitors mechanism of action – inhibition of angiotensin II and bradykinin elevation

Introduction ACE inhibitors (Angiotensin-Converting Enzyme Inhibitors) are a foundational class of antihypertensive drugs. They are used to treat … Read more

Amoxicillin – Mechanism of Action

May 27, 2025 by Harsh Singh Rajput
Amoxicillin mechanism of action – inhibition of bacterial cell wall synthesis via PBPs

Introduction Amoxicillin is a widely used broad-spectrum penicillin antibiotic belonging to the β-lactam class. It is effective against … Read more

Metformin – Mechanism of Action

May 26, 2025 by Harsh Singh Rajput
Metformin mechanism of action – inhibition of gluconeogenesis and activation of AMPK

Introduction Metformin is the first-line oral antidiabetic drug used in the treatment of type 2 diabetes mellitus. It … Read more

Furosemide – Mechanism of Action

May 26, 2025 by Harsh Singh Rajput
Metformin mechanism of action – inhibition of gluconeogenesis and activation of AMPK

Introduction Furosemide, also known by its brand name Lasix, is a potent loop diuretic widely used in clinical … Read more

Mechanism of Action of Omeprazole

July 4, 2025May 26, 2025 by Harsh Singh Rajput
mechanism of action of omeprazole – proton pump inhibition in gastric parietal cells

Introduction Omeprazole is a commonly prescribed drug used to reduce gastric acid secretion. It belongs to the class … Read more

Mechanism of Action of Atorvastatin

May 26, 2025May 26, 2025 by Harsh Singh Rajput
Atorvastatin mechanism of action – HMG-CoA reductase inhibition and LDL receptor upregulation

🔍 Introduction Atorvastatin is a widely used lipid-lowering agent that belongs to the class of HMG-CoA reductase inhibitors, … Read more

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