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USMLE

Mechanism of Action of Amlodipine (Calcium Channel Blocker)

June 23, 2025 by Harsh Singh Rajput
Amlodipine MOA – L-type calcium channel blocker causing vasodilation

Introduction Amlodipine is a commonly prescribed dihydropyridine calcium channel blocker (CCB) used in the treatment of hypertension, angina … Read more

Mechanism of Action of Amiodarone (Class III Antiarrhythmic)

June 23, 2025 by Harsh Singh Rajput
Amiodarone MOA – Multi-class antiarrhythmic with K⁺ channel blockade

Introduction Amiodarone is a powerful Class III antiarrhythmic agent used to treat various life-threatening cardiac arrhythmias, including ventricular … Read more

Mechanism of Action of Warfarin (Vitamin K Antagonist)

June 23, 2025 by Harsh Singh Rajput
Warfarin MOA – Inhibition of vitamin K-dependent clotting factors

Introduction Warfarin is a widely used oral anticoagulant that inhibits the synthesis of vitamin K-dependent clotting factors. It … Read more

Mechanism of Action of Colchicine (Anti-inflammatory in Gout)

June 23, 2025 by Harsh Singh Rajput
Colchicine MOA – Inhibition of microtubule polymerization in neutrophils

Introduction Colchicine is an anti-inflammatory drug primarily used in the management of acute gouty arthritis, familial Mediterranean fever, … Read more

Mechanism of Action of Clopidogrel (Antiplatelet Agent)

June 23, 2025 by Harsh Singh Rajput
Clopidogrel MOA – P2Y12 Receptor Inhibition on Platelets

Introduction Clopidogrel is a widely used oral antiplatelet drug belonging to the thienopyridine class. It plays a critical … Read more

Mechanism of Action of Proton Pump Inhibitors (PPIs)

June 23, 2025 by Harsh Singh Rajput
Proton Pump Inhibitor MOA – H⁺/K⁺ ATPase Inhibition

Introduction Proton Pump Inhibitors (PPIs) are potent acid-suppressing drugs widely used in the treatment of gastric and duodenal … Read more

Mechanism of Action of Benzodiazepines (CNS Depressants)

June 23, 2025June 23, 2025 by Harsh Singh Rajput
Benzodiazepine MOA – GABA-A receptor binding and chloride channel modulation

Introduction Benzodiazepines are a widely used class of central nervous system (CNS) depressants known for their anxiolytic, sedative, … Read more

Mechanism of Action of Metronidazole (DNA-Damaging Antibiotic)

June 23, 2025June 22, 2025 by Harsh Singh Rajput
Metronidazole MOA – DNA damage via nitro radical formation

Introduction Metronidazole is a unique antibiotic and antiprotozoal agent that exerts its action by damaging DNA in anaerobic … Read more

Mechanism of Action of Linezolid (Oxazolidinone Antibiotics)

June 23, 2025June 22, 2025 by Harsh Singh Rajput
Linezolid MOA – 50S ribosomal subunit and initiation inhibition

Introduction Linezolid is a synthetic bacteriostatic antibiotic belonging to the oxazolidinone class. It is primarily active against Gram-positive … Read more

Mechanism of Action of Sulfonamides (Folic Acid Synthesis Inhibitors)

June 23, 2025June 21, 2025 by Harsh Singh Rajput
Sulfonamide MOA – Folic acid synthesis inhibition via dihydropteroate synthase

Introduction Sulfonamides are synthetic bacteriostatic antibiotics that inhibit folic acid synthesis in bacteria. Because mammals obtain folate from … Read more

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Recent Posts

  • Mechanism of Action of Amlodipine (Calcium Channel Blocker)
  • Mechanism of Action of Amiodarone (Class III Antiarrhythmic)
  • Mechanism of Action of Warfarin (Vitamin K Antagonist)
  • Mechanism of Action of Colchicine (Anti-inflammatory in Gout)
  • Mechanism of Action of Clopidogrel (Antiplatelet Agent)
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