Mechanism of Action of Entyvio (Vedolizumab)
Introduction Entyvio (vedolizumab) is a recombinant humanized IgG1 monoclonal antibody that targets the α4β7 integrin on gut-homing T-lymphocytes. … Read more
Ulcerative Colitis
Mechanism of Action of Tofacitinib (Xeljanz)
Introduction Tofacitinib is an oral Janus kinase (JAK) inhibitor, primarily targeting JAK1 and JAK3. It blocks intracellular signaling … Read more
Mechanism of Action of Stelara (Ustekinumab)
Introduction Stelara (ustekinumab) is a fully human IgG1κ monoclonal antibody designed to target key cytokines involved in immune-mediated … Read more