Mechanism of Action of Infliximab (Remicade)
Introduction Infliximab is a chimeric (murine-human) IgG1 monoclonal antibody that targets tumor necrosis factor‑α (TNF‑α). It is used … Read more
Rheumatoid Arthritis
Mechanism of Action of Adalimumab (Humira)
Introduction Adalimumab is a fully human monoclonal IgG1 antibody that specifically targets tumor necrosis factor‑α (TNF‑α). By neutralizing … Read more
Mechanism of Action of Etanercept (Enbrel)
Introduction Etanercept is a biologic fusion protein that functions as a soluble tumor necrosis factor (TNF) receptor. By … Read more
Mechanism of Action of Tocilizumab
Introduction Tocilizumab is a humanized monoclonal antibody targeting the interleukin-6 receptor (IL-6R). It is approved for rheumatoid arthritis … Read more
Mechanism of Action of Anakinra
Introduction Anakinra is a recombinant human interleukin‑1 receptor antagonist (IL‑1Ra) used to treat rheumatoid arthritis, neonatal-onset multisystem inflammatory … Read more