Mechanism of Action of Tofacitinib (Xeljanz)
Introduction Tofacitinib is an oral Janus kinase (JAK) inhibitor, primarily targeting JAK1 and JAK3. It blocks intracellular signaling … Read more
PharmD Study Notes
Mechanism of Action of Semaglutide
Introduction Semaglutide is a long-acting glucagon-like peptide-1 receptor agonist (GLP-1 RA) used for type 2 diabetes mellitus (T2DM) management … Read more
Mechanism of Action of Tolvaptan
Introduction Tolvaptan is an oral vasopressin V₂ receptor antagonist, approved for treating hyponatremia due to SIADH, heart failure, … Read more
Mechanism of Action of Jardiance (Empagliflozin)
Introduction Jardiance (empagliflozin) is a sodium–glucose co-transporter 2 (SGLT2) inhibitor used for type 2 diabetes mellitus (T2DM), heart failure … Read more
Mechanism of Action of Vericiguat (Verquvo)
Introduction Vericiguat is a soluble guanylate cyclase (sGC) stimulator used in patients with chronic heart failure with reduced … Read more
Mechanism of Action of Anakinra
Introduction Anakinra is a recombinant human interleukin‑1 receptor antagonist (IL‑1Ra) used to treat rheumatoid arthritis, neonatal-onset multisystem inflammatory … Read more
Mechanism of Action of Farxiga (Dapagliflozin)
Introduction Dapagliflozin (trade name Farxiga) is a sodium–glucose co‑transporter 2 (SGLT2) inhibitor used in type 2 diabetes mellitus (T2DM) and … Read more
Mechanism of Action of Semaglutide (Ozempic/Wegovy)
Introduction Semaglutide (Ozempic for diabetes; Wegovy for obesity) is a GLP‑1 receptor agonist used for type 2 diabetes mellitus … Read more
Mechanism of Action of Bupropion
Introduction Bupropion is an atypical antidepressant primarily used to treat major depressive disorder, seasonal affective disorder, and as … Read more
Mechanism of Action of Lokelma (Sodium Zirconium Cyclosilicate)
Introduction Lokelma is an oral, non-absorbed potassium binder used to treat hyperkalemia. It works by selectively trapping potassium … Read more