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PharmD Notes

Mechanism of Action of Aripiprazole (Abilify)

July 7, 2025 by Harsh Singh Rajput
Mechanism of action of Aripiprazole

Introduction Aripiprazole is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, major depressive disorder (as adjunct), irritability … Read more

Mechanism of Action of Infliximab (Remicade)

July 6, 2025 by Harsh Singh Rajput
Mechanism of action of Infliximab

Introduction Infliximab is a chimeric (murine-human) IgG1 monoclonal antibody that targets tumor necrosis factor‑α (TNF‑α). It is used … Read more

Mechanism of Action of Dapagliflozin

July 6, 2025 by Harsh Singh Rajput
Mechanism of action of Dapagliflozin

Introduction Dapagliflozin is an oral sodium–glucose co-transporter 2 (SGLT2) inhibitor, used to treat type 2 diabetes mellitus (T2DM). … Read more

Mechanism of Action of Vortioxetine

July 6, 2025 by Harsh Singh Rajput
Mechanism of action of Vortioxetine

Introduction Vortioxetine is a multimodal antidepressant approved for major depressive disorder (MDD). It uniquely combines serotonin transporter (SERT) … Read more

Mechanism of Action of Natalizumab (Tysabri)

July 5, 2025 by Harsh Singh Rajput
Mechanism of action of Natalizumab

Introduction Natalizumab is a humanized IgG4 monoclonal antibody targeting the α4 integrin subunit. It’s approved for relapsing-remitting multiple … Read more

Mechanism of Action of Remdesivir (Veklury)

July 5, 2025 by Harsh Singh Rajput
Mechanism of action of Remdesivir

Introduction Remdesivir is an intravenous antiviral prodrug that inhibits viral RNA-dependent RNA polymerase (RdRp). Originally developed for Ebola, … Read more

Mechanism of Action of Entyvio (Vedolizumab)

July 4, 2025 by Harsh Singh Rajput
Mechanism of action of Entyvio

Introduction Entyvio (vedolizumab) is a recombinant humanized IgG1 monoclonal antibody that targets the α4β7 integrin on gut-homing T-lymphocytes. … Read more

Mechanism of Action of Etanercept (Enbrel)

July 4, 2025 by Harsh Singh Rajput
Mechanism of action of Etanercept

Introduction Etanercept is a biologic fusion protein that functions as a soluble tumor necrosis factor (TNF) receptor. By … Read more

Mechanism of Action of Liraglutide

July 3, 2025 by Harsh Singh Rajput
Mechanism of action of Liraglutide

Introduction Liraglutide is a long-acting GLP‑1 receptor agonist, injected once daily. It’s used for type 2 diabetes mellitus … Read more

Mechanism of Action of SGLT2Inhibitors

July 3, 2025 by Harsh Singh Rajput
Mechanism of action of SGLT2 inhibitors

Introduction SGLT2 inhibitors, also known as “gliflozins,” are a class of oral antidiabetic agents primarily used to manage … Read more

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