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Mechanism of Action of Sulfonylureas

May 31, 2025 by Harsh Singh Rajput
Sulfonylureas mechanism – insulin secretion via KATP channel inhibition

Introduction Sulfonylureas are one of the oldest and most widely used classes of oral antidiabetic agents. They are … Read more

Mechanism of Action of Potassium-Sparing Diuretics

May 31, 2025 by Harsh Singh Rajput
Potassium-sparing diuretics mechanism – aldosterone antagonism and ENaC blockade

Introduction Potassium-sparing diuretics are a unique subclass of diuretics that help conserve potassium levels while promoting mild diuresis. … Read more

Mechanism of Action of Thiazide Diuretics

May 30, 2025 by Harsh Singh Rajput
Thiazide diuretics mechanism – inhibition of sodium chloride symporter in the distal tubule

Introduction Thiazide diuretics are one of the most commonly prescribed classes of antihypertensive agents, especially in the U.S. … Read more

Mechanism of Action of Calcium Channel Blockers (CCBs)

May 27, 2025 by Harsh Singh Rajput
Calcium channel blockers mechanism – L-type calcium channel inhibition and vasodilation

Introduction Calcium Channel Blockers (CCBs) are a major class of antihypertensive and anti-anginal medications. They work by blocking … Read more

Mechanism of Action of Angiotensin II Receptor Blockers (ARBs)

May 27, 2025 by Harsh Singh Rajput
Angiotensin II receptor blockers mechanism – inhibition of AT1-mediated vasoconstriction

Introduction Angiotensin II Receptor Blockers (ARBs) are a major class of antihypertensive drugs. They selectively block the angiotensin … Read more

Amoxicillin – Mechanism of Action

May 27, 2025 by Harsh Singh Rajput
Amoxicillin mechanism of action – inhibition of bacterial cell wall synthesis via PBPs

Introduction Amoxicillin is a widely used broad-spectrum penicillin antibiotic belonging to the β-lactam class. It is effective against … Read more

Mechanism of Action of Atorvastatin

May 26, 2025May 26, 2025 by Harsh Singh Rajput
Atorvastatin mechanism of action – HMG-CoA reductase inhibition and LDL receptor upregulation

🔍 Introduction Atorvastatin is a widely used lipid-lowering agent that belongs to the class of HMG-CoA reductase inhibitors, … Read more

Escitalopram – Mechanism of Action

May 26, 2025May 25, 2025 by Harsh Singh Rajput
Escitalopram mechanism of action – selective serotonin reuptake inhibition and enhanced serotonergic transmission

🔍 Introduction Escitalopram is a widely prescribed antidepressant belonging to the class of Selective Serotonin Reuptake Inhibitors (SSRIs). … Read more

Paracetamol – Mechanism of Action

May 26, 2025May 25, 2025 by Harsh Singh Rajput
Paracetamol mechanism of action – central COX inhibition and antipyretic action via hypothalamus

Introduction Paracetamol (also known as Acetaminophen) is one of the most commonly used drugs for fever and mild-to-moderate … Read more

Methotrexate – Mechanism of Action

May 26, 2025May 25, 2025 by Harsh Singh Rajput
Flowchart of Methotrexate mechanism of action showing DHFR inhibition and suppression of DNA synthesis in S-phase

Introduction Methotrexate is a cornerstone drug in both anticancer chemotherapy and immunosuppressive therapy. Structurally, it is a folic … Read more

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