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Mechanism of Action of Fluoroquinolones (DNA Gyrase and Topoisomerase Inhibitors)

July 4, 2025June 20, 2025 by Harsh Singh Rajput
Fluoroquinolone MOA – Inhibition of DNA gyrase and topoisomerase

Introduction Fluoroquinolones are a powerful class of bactericidal antibiotics that inhibit bacterial DNA replication. They are widely used … Read more

Mechanism of Action of Macrolides (Protein Synthesis Inhibitor Antibiotics)

June 23, 2025June 20, 2025 by Harsh Singh Rajput
Macrolide MOA – 50S ribosome binding and protein synthesis inhibition

Introduction Macrolides are a widely used class of bacteriostatic antibiotics that inhibit bacterial protein synthesis. They are especially … Read more

Mechanism of Action of Penicillins (β-lactam Antibiotics)

June 23, 2025June 19, 2025 by Harsh Singh Rajput
Penicillins MOA – Cell wall synthesis inhibition

Introduction Penicillins are one of the oldest and most widely used classes of antibiotics, belonging to the β-lactam … Read more

Mechanism of Action of Gabapentin

July 4, 2025June 3, 2025 by Harsh Singh Rajput
Gabapentin MOA – calcium channel modulator in epilepsy and neuropathic pain

Introduction Gabapentin is an antiepileptic drug and one of the most widely prescribed medications for neuropathic pain, postherpetic … Read more

Mechanism of Action of Topiramate

June 3, 2025 by Harsh Singh Rajput
Topiramate MOA – GABA enhancer, AMPA blocker, sodium channel inhibitor

Introduction Topiramate is a broad-spectrum antiepileptic drug (AED) known for its use in treating partial and generalized seizures, … Read more

Mechanism of Action of Phenytoin

June 3, 2025 by Harsh Singh Rajput
Phenytoin MOA – voltage-gated sodium channel blocker

Introduction Phenytoin is one of the oldest and most widely used antiepileptic drugs (AEDs), primarily for treating focal … Read more

Mechanism of Action of Levetiracetam

June 3, 2025 by Harsh Singh Rajput
Levetiracetam MOA – SV2A modulation in epilepsy

Introduction Levetiracetam is a novel, broad-spectrum antiepileptic drug (AED) used in the treatment of partial seizures, myoclonic seizures, … Read more

Mechanism of Action of Lamotrigine

June 3, 2025 by Harsh Singh Rajput
Lamotrigine MOA – sodium channel blocker and glutamate inhibitor

Introduction Lamotrigine is a broad-spectrum antiepileptic drug (AED) and an effective mood stabilizer, especially in bipolar depression. It … Read more

Mechanism of Action of Carbamazepine

June 3, 2025 by Harsh Singh Rajput
Carbamazepine mechanism of action – sodium channel blocker in epilepsy and neuralgia

Introduction Carbamazepine is a classic antiepileptic drug (AED) and mood stabilizer. It is mainly used to treat partial … Read more

Mechanism of Action of Valproate (Mood Stabilizer & Antiepileptic)

June 3, 2025 by Harsh Singh Rajput
Valproate mechanism of action – GABA elevation and ion channel blockade

Introduction Valproate (also known as valproic acid or divalproex sodium) is a widely used mood stabilizer and broad-spectrum … Read more

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