MCQ Quiz: Lymphatic System

The lymphatic system is a vital component of the circulatory and immune systems, making its study essential for B.Pharm students. It plays a crucial role in maintaining fluid balance, absorbing fats, and defending the body against pathogens. Understanding the functions of lymphatic organs, the circulation of lymph, and its interaction with the bloodstream provides a critical framework for comprehending immunology, drug distribution, and the body’s response to infections and therapies.


  1. Which of the following is a primary function of the lymphatic system?
    • Transporting oxygen to tissues
    • Producing hormones
    • Returning interstitial fluid to the bloodstream
    • Regulating body temperature
    Answer: Returning interstitial fluid to the bloodstream
  2. The fluid collected by the lymphatic vessels is known as:
    • Plasma
    • Serum
    • Lymph
    • Cytosol
    Answer: Lymph
  3. Which of these is considered a primary lymphatic organ?
    • Spleen
    • Lymph node
    • Thymus
    • Tonsil
    Answer: Thymus
  4. Lymphatic vessels are most similar in structure to:
    • Arteries
    • Veins
    • Capillaries
    • Nerves
    Answer: Veins
  5. The largest lymphatic organ in the body is the:
    • Thymus
    • Spleen
    • Appendix
    • Tonsil
    Answer: Spleen
  6. What is the main function of lymph nodes?
    • To produce lymph
    • To filter lymph and house immune cells
    • To produce red blood cells
    • To secrete hormones
    Answer: To filter lymph and house immune cells
  7. The thoracic duct drains lymph from which part of the body?
    • The right arm and right side of the head
    • The left side of the body and the lower body
    • Only the thorax
    • Only the lower limbs
    Answer: The left side of the body and the lower body
  8. Where do T lymphocytes (T cells) mature?
    • Red bone marrow
    • Spleen
    • Lymph nodes
    • Thymus
    Answer: Thymus
  9. What component is present in blood but absent in lymph?
    • Water
    • White blood cells
    • Red blood cells
    • Proteins
    Answer: Red blood cells
  10. The right lymphatic duct drains lymph into which blood vessel?
    • Left subclavian vein
    • Right subclavian vein
    • Aorta
    • Inferior vena cava
    Answer: Right subclavian vein
  11. Aggregates of lymphatic tissue found in the throat are known as:
    • Peyer’s patches
    • Tonsils
    • Lymph nodes
    • The spleen
    Answer: Tonsils
  12. The flow of lymph through lymphatic vessels is primarily driven by:
    • The pumping action of the heart
    • High pressure from the arteries
    • The contraction of surrounding skeletal muscles
    • The pull of gravity
    Answer: The contraction of surrounding skeletal muscles
  13. Which of the following is a function of the spleen?
    • Maturation of T cells
    • Filtering blood and removing old erythrocytes
    • Producing bile
    • Absorbing fats
    Answer: Filtering blood and removing old erythrocytes
  14. Lymphatic capillaries are different from blood capillaries because they:
    • Are impermeable to proteins
    • Are closed at one end
    • Do not have valves
    • Are smaller in diameter
    Answer: Are closed at one end
  15. The primary site of B cell maturation is the:
    • Thymus
    • Spleen
    • Red bone marrow
    • Liver
    Answer: Red bone marrow
  16. MALT is an acronym for:
    • Multiple Associated Lymphatic Trunks
    • Main Artery and Lymphatic Tissue
    • Mucosa-Associated Lymphatic Tissue
    • Major Antibody and Lymphocyte Tracker
    Answer: Mucosa-Associated Lymphatic Tissue
  17. Lymph enters a lymph node through which vessels?
    • Efferent lymphatic vessels
    • Afferent lymphatic vessels
    • Cortical sinuses
    • The hilum
    Answer: Afferent lymphatic vessels
  18. The thymus gland is most active during which period of life?
    • Childhood
    • Adulthood
    • Old age
    • Puberty
    Answer: Childhood
  19. Specialized lymphatic capillaries in the small intestine that absorb fats are called:
    • Lacteals
    • Cisternae
    • Trunks
    • Ducts
    Answer: Lacteals
  20. Which of the following is NOT a lymphatic organ?
    • Spleen
    • Thymus
    • Liver
    • Tonsil
    Answer: Liver
  21. The inner region of a lymph node is known as the:
    • Cortex
    • Medulla
    • Capsule
    • Trabecula
    Answer: Medulla
  22. The thoracic duct begins as a dilated sac called the:
    • Right lymphatic duct
    • Cisterna chyli
    • Hilum
    • Lacteal
    Answer: Cisterna chyli
  23. Which cell type is found in abundance within lymphatic organs and tissues?
    • Erythrocytes
    • Platelets
    • Lymphocytes
    • Osteocytes
    Answer: Lymphocytes
  24. The main role of the thymus is associated with the:
    • Cardiovascular system
    • Endocrine system
    • Immune system
    • Digestive system
    Answer: Immune system
  25. The tonsils located at the base of the tongue are the:
    • Palatine tonsils
    • Pharyngeal tonsils
    • Lingual tonsils
    • Tubal tonsils
    Answer: Lingual tonsils
  26. Which statement about lymph circulation is correct?
    • It is a high-pressure system.
    • It flows in a one-way direction towards the heart.
    • It is pumped by a central lymphatic heart.
    • It contains numerous red blood cells.
    Answer: It flows in a one-way direction towards the heart.
  27. The white pulp of the spleen is primarily composed of:
    • Macrophages
    • Red blood cells
    • Lymphocytes
    • Platelets
    Answer: Lymphocytes
  28. Lymphatic tissues are strategically located in the body to:
    • Aid in digestion
    • Produce hormones
    • Intercept pathogens before they reach vital organs
    • Store fat
    Answer: Intercept pathogens before they reach vital organs
  29. Which of the following is a secondary lymphatic organ?
    • Red bone marrow
    • Thymus
    • Lymph node
    • Both A and B
    Answer: Lymph node
  30. Peyer’s patches are clusters of lymphatic tissue found in the:
    • Stomach
    • Lungs
    • Small intestine
    • Liver
    Answer: Small intestine
  31. The outer region of a lymph node is called the:
    • Medulla
    • Cortex
    • Hilum
    • Sinus
    Answer: Cortex
  32. Lymph exits a lymph node via the:
    • Afferent lymphatic vessels
    • Efferent lymphatic vessels
    • Trabeculae
    • Lymphatic capillaries
    Answer: Efferent lymphatic vessels
  33. The red pulp of the spleen functions to:
    • House lymphocytes
    • Remove worn-out blood cells and platelets
    • Mature T cells
    • Absorb fats
    Answer: Remove worn-out blood cells and platelets
  34. The lymphatic system helps absorb which type of nutrient from the digestive tract?
    • Carbohydrates
    • Proteins
    • Water-soluble vitamins
    • Fats
    Answer: Fats
  35. Swollen and tender lymph nodes often indicate the presence of:
    • A heart condition
    • An infection
    • A bone fracture
    • High blood pressure
    Answer: An infection
  36. All lymph eventually returns to the bloodstream via the:
    • Aorta and vena cava
    • Portal vein
    • Subclavian veins
    • Pulmonary artery
    Answer: Subclavian veins
  37. The pharyngeal tonsils are also known as the:
    • Lingual tonsils
    • Palatine tonsils
    • Adenoids
    • Peyer’s patches
    Answer: Adenoids
  38. The primary cells responsible for the immune functions of the lymphatic system are:
    • Neutrophils and Eosinophils
    • T-lymphocytes and B-lymphocytes
    • Monocytes and Basophils
    • Erythrocytes and Thrombocytes
    Answer: T-lymphocytes and B-lymphocytes
  39. Which of these structures does NOT contain lymphatic tissue?
    • Spleen
    • Tonsils
    • Brain
    • Appendix
    Answer: Brain
  40. The lymphatic system plays a role in maintaining fluid balance by:
    • Producing excess fluid
    • Draining excess interstitial fluid
    • Storing water in lymph nodes
    • Regulating urine output
    Answer: Draining excess interstitial fluid
  41. B cells are named because they mature in the:
    • Brain
    • Bursa of Fabricius (in birds) / Bone marrow (in mammals)
    • Blood
    • Basophils
    Answer: Bursa of Fabricius (in birds) / Bone marrow (in mammals)
  42. The framework of soft organs like the spleen and lymph nodes is provided by:
    • Collagen fibers
    • Elastic fibers
    • Reticular fibers
    • Muscle fibers
    Answer: Reticular fibers
  43. The two primary lymphatic organs are where lymphocytes:
    • Are cloned
    • Encounter antigens
    • Become immunocompetent
    • Are destroyed
    Answer: Become immunocompetent
  44. Which of these is the smallest lymphatic vessel?
    • Duct
    • Trunk
    • Capillary
    • Collecting vessel
    Answer: Capillary
  45. What is the function of the valves found within lymphatic vessels?
    • To filter the lymph
    • To speed up lymph flow
    • To prevent the backflow of lymph
    • To produce lymphocytes
    Answer: To prevent the backflow of lymph
  46. The spleen is located in which quadrant of the abdominal cavity?
    • Right upper quadrant
    • Left upper quadrant
    • Right lower quadrant
    • Left lower quadrant
    Answer: Left upper quadrant
  47. Edema is the condition of:
    • High blood pressure
    • Excessive interstitial fluid accumulation
    • Low red blood cell count
    • A moving blood clot
    Answer: Excessive interstitial fluid accumulation
  48. Which of the following is NOT a function of the lymphatic system?
    • Regulation of blood glucose
    • Lipid absorption
    • Immune defense
    • Fluid recovery
    Answer: Regulation of blood glucose
  49. After leaving the collecting ducts, lymph enters the:
    • Lymph nodes
    • Lymphatic trunks
    • Blood capillaries
    • Spleen
    Answer: Lymphatic trunks
  50. The formation of lymph increases as a result of:
    • Decreasing blood pressure
    • Increasing hydrostatic pressure in interstitial fluid
    • Increasing osmotic pressure in blood capillaries
    • Decreasing permeability of blood capillaries
    Answer: Increasing hydrostatic pressure in interstitial fluid

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