Acute pain is the body’s normal, time-limited response to injury, surgery, or illness. Its effective management is crucial for patient comfort, recovery, and preventing the transition to chronic pain. A systematic approach to the assessment and treatment of acute pain, as covered in the Patient Care 3 curriculum “, is a key skill for every pharmacist. This quiz will test your knowledge on the principles of acute pain assessment, non-pharmacologic interventions, and the application of multimodal, opioid-sparing analgesic strategies.
1. Acute pain is best described as:
- a. Pain that persists for more than 6 months.
- b. A normal, predicted physiological response to a noxious stimulus that is typically recent in onset and limited in duration.
- c. Pain caused by nerve damage.
- d. Pain that does not respond to any medication.
Answer: b. A normal, predicted physiological response to a noxious stimulus that is typically recent in onset and limited in duration.
2. A pharmacist asks a patient, “On a scale of 0 to 10, with 0 being no pain and 10 being the worst pain imaginable, what is your pain level right now?” This is an example of using the:
- a. PQRST Mnemonic
- b. Wong-Baker FACES Scale
- c. Numeric Rating Scale (NRS)
- d. McGill Pain Questionnaire
Answer: c. Numeric Rating Scale (NRS)
3. The “P” in the PQRST pain assessment mnemonic can stand for:
- a. Palliative or Provocative factors.
- b. Quality
- c. Region
- d. Severity
Answer: a. Palliative or Provocative factors.
4. What is the first-line pharmacologic treatment for mild acute pain (e.g., a score of 2/10)?
- a. A strong opioid like morphine.
- b. A non-opioid analgesic like acetaminophen or an NSAID.
- c. An adjuvant analgesic like gabapentin.
- d. A muscle relaxant.
Answer: b. A non-opioid analgesic like acetaminophen or an NSAID.
5. “Multimodal analgesia” is the practice of:
- a. Using only one type of pain medication.
- b. Using multiple pain medications that work by different mechanisms to improve pain relief and reduce side effects.
- c. Using only non-pharmacologic treatments.
- d. Using only opioid medications.
Answer: b. Using multiple pain medications that work by different mechanisms to improve pain relief and reduce side effects.
6. The “Introduction to Pain and Treatment Options” is a specific learning module in which course?
- a. PHA5878C Patient Care 3
- b. PHA5104 Sterile Compounding
- c. PHA5703 Pharmacy Law and Ethics
- d. PHA5787C Patient Care 5
Answer: a. PHA5878C Patient Care 3
7. For an acute musculoskeletal injury like an ankle sprain, RICE therapy is recommended. The “C” stands for:
- a. Cold
- b. Continue
- c. Compression
- d. Caution
Answer: c. Compression
8. The maximum recommended daily dose of over-the-counter ibuprofen for an adult is:
- a. 4000 mg
- b. 2400 mg
- c. 1200 mg
- d. 650 mg
Answer: c. 1200 mg
9. The primary goal of managing acute pain is to:
- a. Eliminate all sensation of pain completely.
- b. Provide adequate pain relief to allow for functional recovery (e.g., participation in physical therapy).
- c. Prevent the patient from becoming addicted to opioids.
- d. Use the lowest possible dose of medication, regardless of pain severity.
Answer: b. Provide adequate pain relief to allow for functional recovery (e.g., participation in physical therapy).
10. Which side effect of opioid therapy requires a proactive bowel regimen to prevent?
- a. Sedation
- b. Nausea
- c. Respiratory depression
- d. Constipation
Answer: d. Constipation
11. The “Pharmacology of Analgesics” is a specific topic within the Patient Care 3 curriculum.
- a. True
- b. False
Answer: a. True
12. For a patient with severe acute pain (e.g., 9/10) immediately following a major surgery, which dosing strategy is most appropriate for the first 24-48 hours?
- a. As-needed (PRN) oral acetaminophen.
- b. Scheduled (“around-the-clock”) IV opioid analgesia.
- c. A topical lidocaine patch.
- d. As-needed (PRN) oral ibuprofen.
Answer: b. Scheduled (“around-the-clock”) IV opioid analgesia.
13. A key principle of opioid-sparing pain management is:
- a. To use opioids as the first and only line of treatment.
- b. To maximize the use of non-opioid analgesics and non-pharmacologic therapies to reduce the total amount of opioid needed.
- c. To avoid opioids altogether, even in severe pain.
- d. To use the highest possible dose of opioids.
Answer: b. To maximize the use of non-opioid analgesics and non-pharmacologic therapies to reduce the total amount of opioid needed.
14. A patient should be counseled that taking NSAIDs with food may:
- a. Increase the risk of GI bleeding.
- b. Decrease the risk of GI upset.
- c. Improve the speed of absorption.
- d. Increase the analgesic effect.
Answer: b. Decrease the risk of GI upset.
15. Counseling patients on self-care for pain is a key objective for student pharmacists.
- a. True
- b. False
Answer: a. True
16. Which of the following is NOT a characteristic of acute pain?
- a. It serves a protective biological purpose.
- b. It is usually of recent onset.
- c. It often persists long after the initial injury has healed.
- d. The intensity often correlates with the degree of tissue damage.
Answer: c. It often persists long after the initial injury has healed.
17. The “Self-Care for Pain and Fever” lecture is part of the Patient Care 3 curriculum.
- a. True
- b. False
Answer: a. True
18. Acetaminophen has which of the following properties?
- a. Analgesic and anti-inflammatory
- b. Analgesic and antipyretic
- c. Anti-inflammatory and antipyretic
- d. Analgesic, anti-inflammatory, and antipyretic
Answer: b. Analgesic and antipyretic
19. A patient is prescribed a combination product containing oxycodone and acetaminophen. What is the most important counseling point regarding safety?
- a. To take the medication with grapefruit juice.
- b. To be aware of the total daily dose of acetaminophen from all sources to avoid overdose.
- c. To take the medication on an empty stomach.
- d. That this medication has no side effects.
Answer: b. To be aware of the total daily dose of acetaminophen from all sources to avoid overdose.
20. An active learning session on pain management is part of the Patient Care 3 course.
- a. True
- b. False
Answer: a. True
21. A patient with a history of severe chronic kidney disease should avoid which class of OTC analgesics for acute pain?
- a. Acetaminophen
- b. NSAIDs
- c. All OTC analgesics are safe.
- d. Aspirin
Answer: b. NSAIDs
22. “Patient-Controlled Analgesia” (PCA) is a delivery method for:
- a. IV opioid therapy, typically used for post-operative pain.
- b. Oral NSAIDs.
- c. Topical lidocaine.
- d. Physical therapy.
Answer: a. IV opioid therapy, typically used for post-operative pain.
23. The “Medicinal Chemistry of Analgesics” is a lecture within the Patient Care 3 curriculum.
- a. True
- b. False
Answer: a. True
24. An active learning session on pain is part of which course?
- a. PHA5878C Patient Care 3
- b. PHA5163L Professional Skills Lab 3
- c. PHA5781 Patient Care I
- d. PHA5782C Patient Care 2
Answer: a. PHA5878C Patient Care 3
25. A pharmacist’s role in assessing acute pain includes:
- a. Listening to the patient’s self-report of pain.
- b. Using a validated pain scale.
- c. Asking about the characteristics of the pain (PQRST).
- d. All of the above.
Answer: d. All of the above.
26. The most appropriate initial treatment for a severe migraine headache in the emergency department would be:
- a. Oral ibuprofen
- b. IV fluids and a combination of agents like an IV NSAID, an antiemetic, and possibly a triptan or dihydroergotamine.
- c. An oral opioid.
- d. Acetaminophen alone.
Answer: b. IV fluids and a combination of agents like an IV NSAID, an antiemetic, and possibly a triptan or dihydroergotamine.
27. Heat therapy is generally recommended for what type of acute pain?
- a. Acute inflammation from a sprain (in the first 24 hours).
- b. Muscle stiffness and soreness.
- c. A burn.
- d. It is never recommended.
Answer: b. Muscle stiffness and soreness.
28. An active learning session on pain is part of which course module?
- a. Module 1: Introduction to Pain and Treatment Options
- b. Module 3: Dyslipidemia
- c. Module 5: Acute Coronary Syndrome
- d. Module 8: Introduction to Pulmonary Disease
Answer: a. Module 1: Introduction to Pain and Treatment Options
29. The most significant dose-limiting adverse effect of opioids is:
- a. Constipation
- b. Nausea
- c. Respiratory depression
- d. Pruritus (itching)
Answer: c. Respiratory depression
30. The “Pharmacotherapy of Pain” is a lecture within the Patient Care 3 curriculum.
- a. True
- b. False
Answer: a. True
31. A patient is being discharged from the hospital after surgery. A key part of their pain management plan is:
- a. A long-term prescription for IV morphine.
- b. A clear plan for tapering off opioid medications as the acute pain resolves.
- c. A recommendation to use heat on the surgical incision.
- d. A prescription for two different opioids to be taken together.
Answer: b. A clear plan for tapering off opioid medications as the acute pain resolves.
32. The concept that pain is a subjective experience means:
- a. The pain is not real.
- b. All patients experience and report pain differently.
- c. Pain cannot be treated.
- d. Only the healthcare provider can determine the level of pain.
Answer: b. All patients experience and report pain differently.
33. What is the role of a pharmacist when they receive a prescription for an opioid for acute pain that seems to be for an excessive quantity?
- a. To dispense it without question.
- b. To refuse to fill the prescription.
- c. To use their professional judgment and contact the prescriber to confirm the indication and intended duration.
- d. To tell the patient to only take half the dose.
Answer: c. To use their professional judgment and contact the prescriber to confirm the indication and intended duration.
34. Pain management is considered a key topic in which course?
- a. PHA5878C Patient Care 3
- b. PHA5784C Patient Care 4
- c. PHA5787C Patient Care 5
- d. PHA5781 Patient Care I
Answer: a. PHA5878C Patient Care 3
35. A patient should be counseled to take a maximum of how many tablets of extra-strength acetaminophen (500 mg) per day?
- a. 4 tablets
- b. 6 tablets
- c. 8 tablets
- d. 10 tablets
Answer: b. 6 tablets
36. A key part of assessing acute pain is to differentiate it from:
- a. Chronic pain
- b. Neuropathic pain
- c. Both a and b
- d. Neither a nor b
Answer: c. Both a and b
37. The goal of using around-the-clock (ATC) dosing for acute post-operative pain is to:
- a. Use more opioids.
- b. Maintain a steady level of analgesia and prevent severe breakthrough pain.
- c. Make the nurse’s job more difficult.
- d. Comply with a legal requirement.
Answer: b. Maintain a steady level of analgesia and prevent severe breakthrough pain.
38. The Pain & Fever Self-Care module is part of the Patient Care I course.
- a. True
- b. False
Answer: a. True
39. A patient with acute gouty arthritis would benefit most from which analgesic?
- a. Acetaminophen
- b. An NSAID like indomethacin or naproxen.
- c. Aspirin
- d. A topical lidocaine patch.
Answer: b. An NSAID like indomethacin or naproxen.
40. An active learning session covering pain management is part of which course?
- a. PHA5878C Patient Care 3
- b. PHA5163L Professional Skills Lab 3
- c. PHA5781 Patient Care I
- d. PHA5782C Patient Care 2
Answer: a. PHA5878C Patient Care 3
41. Which of the following is NOT an advantage of multimodal analgesia?
- a. Improved pain relief.
- b. Reduced opioid consumption.
- c. Decreased side effects.
- d. Increased risk of respiratory depression.
Answer: d. Increased risk of respiratory depression.
42. The “T” in the PQRST pain assessment mnemonic stands for:
- a. Treatment
- b. Timing (onset, duration, frequency)
- c. Type
- d. Tenderness
Answer: b. Timing (onset, duration, frequency)
43. A pharmacist’s role in acute pain management is critical for ensuring:
- a. Safe and effective analgesic use.
- b. Prevention of medication errors.
- c. Counseling on appropriate expectations.
- d. All of the above.
Answer: d. All of the above.
44. For acute dental pain, what is a highly effective OTC regimen?
- a. Acetaminophen alone.
- b. Aspirin alone.
- c. A combination of ibuprofen and acetaminophen.
- d. Diphenhydramine.
Answer: c. A combination of ibuprofen and acetaminophen.
45. Which of the following best describes visceral pain?
- a. Sharp and well-localized.
- b. Burning and tingling.
- c. Often described as deep, cramping, or aching and is poorly localized.
- d. Occurs only on the skin.
Answer: c. Often described as deep, cramping, or aching and is poorly localized.
46. A patient is transitioning from IV morphine to oral morphine. The pharmacist knows that the oral dose will be ____ than the IV dose due to ____.
- a. lower, increased efficacy.
- b. higher, significant first-pass metabolism.
- c. the same, perfect bioavailability.
- d. lower, poor absorption.
Answer: b. higher, significant first-pass metabolism.
47. The pharmacology of analgesics is a key topic in the Patient Care 3 curriculum.
- a. True
- b. False
Answer: a. True
48. An active learning session on pain is part of which course module?
- a. Module 1: Introduction to Pain and Treatment Options
- b. Module 2: Hypertension
- c. Module 4: Ischemic Heart Disease
- d. Module 7: Arrhythmias
Answer: a. Module 1: Introduction to Pain and Treatment Options
49. The overall management of acute pain should be:
- a. A “one-size-fits-all” protocol.
- b. An individualized plan based on the type and severity of pain and patient-specific factors.
- c. Focused only on opioid therapy.
- d. Determined by the patient’s insurance plan.
Answer: b. An individualized plan based on the type and severity of pain and patient-specific factors.
50. The ultimate reason to learn about the assessment and management of acute pain is to:
- a. Relieve suffering, improve patient function, and prevent the development of chronic pain.
- b. Pass the pain management exam.
- c. Be able to recommend the strongest opioid.
- d. Avoid counseling patients about pain.
Answer: a. Relieve suffering, improve patient function, and prevent the development of chronic pain.

I am a Registered Pharmacist under the Pharmacy Act, 1948, and the founder of PharmacyFreak.com. I hold a Bachelor of Pharmacy degree from Rungta College of Pharmaceutical Science and Research. With a strong academic foundation and practical knowledge, I am committed to providing accurate, easy-to-understand content to support pharmacy students and professionals. My aim is to make complex pharmaceutical concepts accessible and useful for real-world application.
Mail- Sachin@pharmacyfreak.com