Classification of tablets MCQs With Answer provides B.Pharm students a focused, exam-oriented review of tablet types, formulation principles, manufacturing methods, and quality-control considerations. This concise guide emphasizes tablet classification by release profile (immediate, delayed, sustained, controlled), physical form (compressed, sugar-coated, film-coated, enteric-coated), and special-category tablets (buccal, sublingual, chewable, effervescent, dispersible). Key topics include excipients, compression techniques, dissolution, stability, and regulatory tests relevant to pharmaceutical dosage forms. MCQs include questions on pharmacokinetics, bioavailability, tablet defects, scale-up, and in-process controls to deepen understanding. Now let’s test your knowledge with 30 MCQs on this topic.
Q1. Which classification of tablets is designed to release the active drug at a predetermined time after administration?
- Immediate-release tablet
- Enteric-coated tablet
- Delayed-release tablet
- Chewable tablet
Correct Answer: Delayed-release tablet
Q2. Which tablet type is specifically formulated to disintegrate and dissolve rapidly in the mouth without water?
- Sublingual tablet
- Effervescent tablet
- Buccal tablet
- Orally disintegrating tablet (ODT)
Correct Answer: Orally disintegrating tablet (ODT)
Q3. Which excipient class primarily improves powder flow and compressibility during tablet manufacturing?
- Diluents/fillers
- Binders
- Lubricants
- Glidants
Correct Answer: Glidants
Q4. Which coating is used to protect a drug from gastric acid and allow release in the intestine?
- Sugar coating
- Film coating
- Enteric coating
- Opadry coating
Correct Answer: Enteric coating
Q5. Which tablet classification describes a formulation that provides drug release at a constant rate over an extended period?
- Sustained-release tablet
- Controlled-release tablet
- Immediate-release tablet
- Dispersible tablet
Correct Answer: Controlled-release tablet
Q6. Which in-process test mainly assesses tablet mechanical strength against abrasive forces?
- Disintegration test
- Friability test
- Hardness test
- Dissolution test
Correct Answer: Friability test
Q7. Which manufacturing step converts fine powders into granules to improve compressibility and uniformity?
- Direct compression
- Wet granulation
- Film coating
- Tablet polishing
Correct Answer: Wet granulation
Q8. Which tablet type is intended to dissolve slowly over mucosal tissue in the mouth for local or systemic effect?
- Buccal tablet
- Immediate-release tablet
- Film-coated tablet
- Effervescent tablet
Correct Answer: Buccal tablet
Q9. Which release mechanism is primarily governed by polymer matrix erosion or diffusion of drug through a polymer?
- Osmotic pump
- Matrix-controlled release
- Enteric protection
- Immediate dissolution
Correct Answer: Matrix-controlled release
Q10. Which tablet defect is indicated by capping or lamination during compression?
- Sticking
- Erosion
- Capping/lamination
- Mottling
Correct Answer: Capping/lamination
Q11. Which quality test measures the time taken for a tablet to break down into particles under specified conditions?
- Hardness test
- Disintegration test
- Dissolution test
- Assay
Correct Answer: Disintegration test
Q12. For direct compression tablets, which property of the drug-excipient blend is most critical?
- Moisture content only
- Flowability and compressibility
- Color uniformity
- Taste masking
Correct Answer: Flowability and compressibility
Q13. Which tablet form is designed to be dissolved in water before administration and often contains effervescent agents?
- Effervescent tablet
- Film-coated tablet
- Sustained-release tablet
- Sublingual tablet
Correct Answer: Effervescent tablet
Q14. Which excipient is primarily used to improve tablet hardness and cohesion by promoting particle binding?
- Lubricants
- Disintegrants
- Binders
- Glidants
Correct Answer: Binders
Q15. Which test provides dissolution profile data that correlates with expected in vivo release and bioavailability?
- Disintegration test
- Dissolution test
- Friability test
- Weight variation test
Correct Answer: Dissolution test
Q16. Which type of tablet uses a semipermeable membrane and an osmotic core to achieve controlled drug release?
- Matrix tablet
- Osmotic pump tablet (osmotic-controlled)
- Immediate-release tablet
- Chewable tablet
Correct Answer: Osmotic pump tablet (osmotic-controlled)
Q17. Which excipient reduces friction between the tablet and die wall and prevents sticking to punches?
- Disintegrant
- Lubricant
- Binder
- Glidant
Correct Answer: Lubricant
Q18. Which classification reflects tablets produced by compressing granules without prior wetting or granulation?
- Wet granulation tablets
- Dry granulation tablets
- Direct compression tablets
- Film-coated tablets
Correct Answer: Direct compression tablets
Q19. Which tablet parameter assesses content uniformity across a batch and ensures each tablet contains the intended API amount?
- Assay/Content uniformity
- Friability
- Disintegration
- Hardness
Correct Answer: Assay/Content uniformity
Q20. Which coating type primarily improves swallowing and appearance but does not significantly control drug release?
- Enteric coating
- Sugar coating
- Sustained-release coating
- Gastro-resistant coating
Correct Answer: Sugar coating
Q21. Which tablet class is formulated for absorption through the sublingual mucosa for rapid systemic effect?
- Sublingual tablet
- Buccal tablet
- Immediate-release tablet
- Film-coated tablet
Correct Answer: Sublingual tablet
Q22. During scale-up, which factor is most likely to change and affect tablet weight variation and content uniformity?
- Packaging material only
- Granule batch size and blending efficiency
- Patient population
- Colorant type
Correct Answer: Granule batch size and blending efficiency
Q23. Which disintegrant action mechanism involves wicking of water into tablet pores to cause rapid breakup?
- Swelling
- Enzymatic hydrolysis
- Wicking/capillary action
- Ion exchange
Correct Answer: Wicking/capillary action
Q24. Which deviation in tablet appearance is typically caused by uneven distribution of colorant during mixing?
- Cracking
- Mottling
- Capping
- Sticking
Correct Answer: Mottling
Q25. Which analytical parameter is critical to assess stability-related potency loss in tablet dosage forms?
- Disintegration time only
- Moisture sorption and assay over time
- Tablet color
- Packaging weight
Correct Answer: Moisture sorption and assay over time
Q26. Which tablet type is intended to provide immediate drug release in the oral cavity and usually used for locally acting agents?
- Buccal tablet
- Chewable tablet
- Immediate-release coated tablet
- Effervescent tablet
Correct Answer: Buccal tablet
Q27. Which manufacturing technique is preferred for moisture-sensitive APIs to avoid exposure to liquids?
- Wet granulation
- Spray drying
- Direct compression
- Coating with aqueous solutions
Correct Answer: Direct compression
Q28. Which mechanism commonly governs release from a hydrophilic matrix tablet formulation?
- Immediate bolus release
- Diffusion through gel layer and erosion
- Osmotic pumping only
- Enteric-triggered release
Correct Answer: Diffusion through gel layer and erosion
Q29. Which regulatory test ensures tablet hardness and friability are within acceptable limits to withstand handling and transport?
- Assay only
- Stability under accelerated conditions only
- Hardness and friability tests
- Color and odor inspection
Correct Answer: Hardness and friability tests
Q30. Which tablet classification emphasizes rapid onset by bypassing first-pass hepatic metabolism through transmucosal absorption?
- Immediate-release oral tablet
- Sustained-release matrix tablet
- Sublingual or buccal tablet
- Enteric-coated tablet
Correct Answer: Sublingual or buccal tablet
I am a Registered Pharmacist under the Pharmacy Act, 1948, and the founder of PharmacyFreak.com. I hold a Bachelor of Pharmacy degree from Rungta College of Pharmaceutical Science and Research. With a strong academic foundation and practical knowledge, I am committed to providing accurate, easy-to-understand content to support pharmacy students and professionals. My aim is to make complex pharmaceutical concepts accessible and useful for real-world application.
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