Urinary Tract Infections MCQ Quiz | Urinary Tract

Welcome to this comprehensive quiz on Urinary Tract Infections (UTIs), designed specifically for MBBS students. This quiz will test your understanding of the etiology, pathophysiology, clinical presentation, diagnosis, and management of various types of UTIs, from uncomplicated cystitis to complicated pyelonephritis. Covering key pathogens like E. coli, diagnostic markers in urinalysis, and appropriate antibiotic regimens, these 25 questions will challenge and reinforce your clinical knowledge. After submitting your answers, you will receive your score and a detailed review highlighting the correct and incorrect responses. For further study and revision, you can download all the questions along with their correct answers in a convenient PDF format. Good luck!

1. What is the most common causative agent of uncomplicated urinary tract infections (UTIs) in women?

2. The presence of which of the following in a urinalysis is most specific for a urinary tract infection?

3. A 28-year-old pregnant woman in her second trimester is diagnosed with asymptomatic bacteriuria. What is the most appropriate management?

4. Which virulence factor of uropathogenic E. coli (UPEC) is primarily associated with pyelonephritis?

5. A patient with an indwelling urinary catheter develops a fever and leukocytosis. The urine culture grows >10^5 CFU/mL of Candida albicans. What is the most crucial first step in management?

6. Which of the following is considered a “complicated” UTI?

7. A 45-year-old male presents with fever, chills, and severe costovertebral angle (CVA) tenderness. Urinalysis shows pyuria and bacteriuria. White blood cell casts are seen on microscopy. What is the most likely diagnosis?

8. Which organism is known for producing urease, leading to alkaline urine and the formation of struvite (magnesium ammonium phosphate) stones?

9. What is the standard definition of a significant bacteriuria in a midstream urine sample for a symptomatic woman?

10. A 22-year-old female presents with a 3-day history of dysuria, frequency, and urgency. She has no fever or flank pain. Which antibiotic is a recommended first-line agent for this condition in a region with low resistance rates?

11. The presence of “sterile pyuria” (leukocytes in urine without bacteria on standard culture) should raise suspicion for which of the following infections?

12. A 68-year-old male with benign prostatic hyperplasia (BPH) presents with recurrent UTIs. The underlying mechanism is most likely related to:

13. Which of the following is a key host defense mechanism against UTIs?

14. A 30-year-old female experiences her fourth UTI in the past 12 months. This condition is best described as:

15. What is the primary mechanism of action of phenazopyridine in the management of UTIs?

16. Which antibiotic should be avoided in the third trimester of pregnancy for treating a UTI due to the risk of neonatal hemolysis?

17. A patient with symptoms of acute pyelonephritis is found to be hypotensive and confused. This condition is best described as:

18. What is the most common route of infection for UTIs?

19. In which population is Staphylococcus saprophyticus a common cause of acute cystitis?

20. The formation of a biofilm on a urinary catheter is a key step in the pathogenesis of CAUTI. Which organism is particularly adept at forming biofilms?

21. A urine dipstick is positive for leukocyte esterase. This indicates the presence of:

22. Why are fluoroquinolones like ciprofloxacin no longer considered first-line for uncomplicated cystitis in many regions?

23. In a patient with an uncomplicated UTI, which of the following is an indication for obtaining a urine culture?

24. What is the main reason women are more susceptible to UTIs than men?

25. Emphysematous pyelonephritis, a severe necrotizing infection of the kidney, is most commonly seen in patients with what underlying condition?

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