Universal Immunization Programme (UIP) MCQs With Answer is a focused resource for B. Pharm students covering India’s flagship immunization strategy. This introduction outlines core concepts: vaccines in the UIP schedule, cold chain management, vaccine-preventable diseases, adverse events following immunization (AEFI), surveillance, program implementation and monitoring, and key initiatives like Mission Indradhanush. Emphasis on technical details — vaccine types, storage temperatures, vial monitoring, session planning, and pharmacovigilance — prepares pharmacy students for clinical, logistical, and regulatory roles. Familiarity with UIP strengthens understanding of public health immunization policy, vaccine safety, and supply-chain challenges. Now let’s test your knowledge with 30 MCQs on this topic.
Q1. What is the primary objective of the Universal Immunization Programme (UIP) in India?
- To provide free medicines for all chronic diseases
- To eliminate all infectious diseases within five years
- To reduce morbidity and mortality from vaccine-preventable diseases
- To export vaccines to other countries
Correct Answer: To reduce morbidity and mortality from vaccine-preventable diseases
Q2. Which of the following vaccines is included in the UIP birth dose?
- Measles–Rubella vaccine
- Hepatitis B vaccine
- Oral Polio Vaccine (OPV) first dose at 6 weeks
- Rotavirus vaccine
Correct Answer: Hepatitis B vaccine
Q3. What is the recommended storage temperature range for most routine vaccines under UIP?
- -20°C to -10°C
- 2°C to 8°C
- 15°C to 25°C
- Below -70°C
Correct Answer: 2°C to 8°C
Q4. Vaccine Vial Monitor (VVM) is used to monitor which parameter?
- Exposure to freezing temperatures
- Accumulated heat exposure
- Sterility breach of vial
- pH changes in vaccine
Correct Answer: Accumulated heat exposure
Q5. Which adjuvant is most commonly used in UIP vaccines to enhance immune response?
- Aluminium salts (alum)
- Monophosphoryl lipid A (MPL)
- Squalene (MF59)
- Complete Freund’s adjuvant
Correct Answer: Aluminium salts (alum)
Q6. The UIP session type conducted at fixed health facilities on predetermined days is called:
- Outreach Session
- Special Immunization Drive
- Fixed Session
- Mass Vaccination Campaign
Correct Answer: Fixed Session
Q7. Which vaccine in UIP is administered orally?
- Inactivated poliovirus vaccine (IPV)
- Oral Polio Vaccine (OPV)
- BCG vaccine
- Pentavalent vaccine
Correct Answer: Oral Polio Vaccine (OPV)
Q8. Which component is NOT part of the cold chain equipment used in UIP?
- Ice-lined refrigerator (ILR)
- Vaccine carrier
- Deep freezers for ultra-cold storage (-150°C)
- Cold box
Correct Answer: Deep freezers for ultra-cold storage (-150°C)
Q9. AEFI stands for:
- Adverse Events Following Immunization
- Age-Exempted For Immunization
- Automated Evaluation of Fertility Index
- Annual Evaluation For Immunity
Correct Answer: Adverse Events Following Immunization
Q10. Which UIP vaccine provides protection against tuberculosis?
- BCG
- Hepatitis B
- Measles–Rubella
- Pneumococcal conjugate vaccine (PCV)
Correct Answer: BCG
Q11. Which vaccine in the UIP is given to adolescents (girls) under school-based HPV program?
- Hepatitis B vaccine
- Human Papillomavirus (HPV) vaccine
- Rotavirus vaccine
- Japanese Encephalitis vaccine
Correct Answer: Human Papillomavirus (HPV) vaccine
Q12. Mission Indradhanush primarily aims to:
- Introduce new vaccines into UIP
- Improve vaccination coverage in underserved areas
- Replace oral vaccines with injectable vaccines
- Provide vitamin supplementation
Correct Answer: Improve vaccination coverage in underserved areas
Q13. Which indicator is commonly used to assess UIP immunization performance?
- Incidence of influenza per 1000
- Percentage coverage of fully immunized children
- Number of vaccine manufacturers
- Annual healthcare expenditure per capita
Correct Answer: Percentage coverage of fully immunized children
Q14. The pentavalent vaccine in UIP combines protection against which diseases?
- Diphtheria, Tetanus, Pertussis, Polio, Measles
- Hepatitis B, Haemophilus influenzae type b, DPT
- BCG, Hepatitis B, Measles, Rubella, JE
- Pneumococcus, Rotavirus, HPV, JE, HepA
Correct Answer: Hepatitis B, Haemophilus influenzae type b, DPT
Q15. What is the multi-dose vial policy (MDVP) primarily designed to address?
- Wastage due to single-dose vials
- Safe reuse of needles
- Use of opened multi-dose vials for subsequent sessions when conditions permit
- Extending vaccine shelf-life beyond manufacturer expiry
Correct Answer: Use of opened multi-dose vials for subsequent sessions when conditions permit
Q16. Which of the following is a heat-sensitive vaccine indicator that changes color irreversibly when exposed to cumulative heat?
- Vaccine Vial Monitor (VVM)
- Thermometer mercury column
- Cold chain alarm
- pH paper strip
Correct Answer: Vaccine Vial Monitor (VVM)
Q17. Which vaccine is contraindicated in severely immunocompromised individuals under UIP?
- Inactivated polio vaccine (IPV)
- Live attenuated measles-containing vaccine
- Hepatitis B vaccine
- Tetanus toxoid
Correct Answer: Live attenuated measles-containing vaccine
Q18. Which organization provides technical support and policy guidance to UIP at international level?
- World Health Organization (WHO)
- World Trade Organization (WTO)
- International Monetary Fund (IMF)
- Federation Internationale de Football Association (FIFA)
Correct Answer: World Health Organization (WHO)
Q19. An AEFI that is severe, unexpected, and possibly related to immunization should be reported to:
- Local hospital billing department
- AEFI surveillance and reporting system at district/state level
- Pharmacy inventory manager
- Vaccine manufacturer only
Correct Answer: AEFI surveillance and reporting system at district/state level
Q20. Which UIP vaccine helps prevent diarrheal hospitalizations due to rotavirus?
- Rotavirus vaccine
- Measles–Rubella vaccine
- Pneumococcal conjugate vaccine (PCV)
- BCG vaccine
Correct Answer: Rotavirus vaccine
Q21. Which cold chain equipment is used to transport vaccines to outreach sessions for short durations?
- Ice-lined refrigerator (ILR)
- Deep freezer
- Vaccine carrier
- Ultra-low temperature freezer
Correct Answer: Vaccine carrier
Q22. Which of the following is a core surveillance activity under UIP for monitoring vaccine-preventable diseases?
- Adverse drug reaction monitoring for antibiotics
- Acute flaccid paralysis (AFP) surveillance for polio
- Monthly pharmacy stock audit
- Annual influenza serosurvey only
Correct Answer: Acute flaccid paralysis (AFP) surveillance for polio
Q23. Which parameter is NOT typically recorded on an immunization card in UIP?
- Date of vaccination
- Vaccine batch number
- Child’s birth weight at delivery
- Name of vaccine administered
Correct Answer: Child’s birth weight at delivery
Q24. The introduction of Injectable Polio Vaccine (IPV) into UIP was primarily to:
- Replace all oral vaccines immediately
- Provide additional protection and reduce vaccine-derived poliovirus risk
- Increase cold chain complexity without benefit
- Be used only in outbreak settings
Correct Answer: Provide additional protection and reduce vaccine-derived poliovirus risk
Q25. Which waste disposal method is recommended in UIP for used syringes and needles?
- Open burning in community areas
- Sharps disposal in puncture-proof containers followed by incineration or deep burial as per guidelines
- Reuse after boiling
- Dispose in regular household garbage
Correct Answer: Sharps disposal in puncture-proof containers followed by incineration or deep burial as per guidelines
Q26. Which vaccine in the UIP contains an inactivated (killed) virus?
- BCG
- Inactivated Polio Vaccine (IPV)
- Measles vaccine
- Oral Polio Vaccine (OPV)
Correct Answer: Inactivated Polio Vaccine (IPV)
Q27. Which documentation is critical for vaccine lot traceability in UIP?
- Vaccine Lot Number and Expiry recorded at point of administration
- Only donor name for batch
- Cold chain equipment serial number only
- Manufacturer invoice without batch details
Correct Answer: Vaccine Lot Number and Expiry recorded at point of administration
Q28. Which of the following best describes a “fully immunized child” as per UIP definitions?
- Child who has received BCG, measles only
- Child who received all UIP recommended vaccines appropriate for age by 12–23 months
- Child who received at least one vaccine dose
- Child vaccinated only during campaigns
Correct Answer: Child who received all UIP recommended vaccines appropriate for age by 12–23 months
Q29. Which of the following is a vaccine-preventable disease targeted by UIP elimination goals?
- Poliomyelitis
- Type 2 diabetes
- Hypertension
- Common cold exclusively
Correct Answer: Poliomyelitis
Q30. Which component of UIP ensures quality of immunization through training, supervision and monitoring?
- Pharmaceutical sales representatives
- Human resource development and capacity building
- Only vaccine procurement
- Advertising campaigns
Correct Answer: Human resource development and capacity building
