Puberty & Adolescence MCQ Quiz | Basic Sciences

Welcome to the Puberty & Adolescence MCQ Quiz, specifically designed for MBBS students navigating the Basic Sciences. This quiz covers the intricate physiological and hormonal changes that define the transition from childhood to adulthood. You will be tested on key topics including the hypothalamic-pituitary-gonadal axis, Tanner staging, physical milestones like menarche and spermarche, and common clinical pathologies such as precocious and delayed puberty. This assessment serves as an excellent tool for self-evaluation and revision, reinforcing crucial concepts for your examinations. Challenge your knowledge with these 25 questions. After submitting, you can review your score, see detailed answer explanations, and download a complete PDF of the questions and correct answers for your future study sessions.

1. What is the primary trigger for the onset of puberty?

2. Which hormone is primarily responsible for thelarche (breast development)?

3. In males, Luteinizing Hormone (LH) primarily stimulates which cells in the testes?

4. The pubertal growth spurt is primarily mediated by the synergistic action of which two hormones?

5. What is the definition of menarche?

6. Tanner stage 2 for female breast development is characterized by:

7. In the Tanner staging for male genital development, a testicular volume of 4 ml signifies the onset of:

8. Which event typically occurs first in female puberty?

9. Adrenarche is characterized by the increased production of which hormones from the adrenal cortex?

10. What is the typical sequence of pubertal events in males?

11. Precocious puberty is defined as the onset of secondary sexual characteristics before what age in girls?

12. Delayed puberty in boys is typically defined as the absence of testicular enlargement by what age?

13. A patient presents with delayed puberty and anosmia (inability to smell). Which genetic disorder is most likely?

14. Which hormone is directly responsible for the epiphyseal closure at the end of puberty in both males and females?

15. Spermarche, the first production of sperm, typically occurs at which Tanner stage of genital development?

16. The negative feedback on GnRH secretion in males is primarily exerted by:

17. What is the most common cause of central precocious puberty (GnRH-dependent)?

18. In peripheral precocious puberty (GnRH-independent), what are the expected levels of LH and FSH after a GnRH stimulation test?

19. Bone age assessment, used to evaluate pubertal development, is most commonly performed using an X-ray of the:

20. The increase in pulsatile GnRH secretion at puberty is thought to be primarily permitted by the action of which neuropeptide?

21. What is the average age of menarche in well-nourished populations?

22. Physiological gynecomastia, a common finding in adolescent boys, is caused by:

23. The term “pubarche” refers to the first appearance of:

24. In females, Follicle-Stimulating Hormone (FSH) is primarily responsible for:

25. During adolescence, which part of the brain undergoes significant maturation, affecting decision-making and impulse control?

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