Plasma Proteins MCQ Quiz | Biomolecules

Welcome to the Plasma Proteins Quiz for MBBS students. This quiz is designed to test your understanding of the major plasma proteins, their functions, synthesis, and clinical significance within the Biomolecules syllabus. You will be challenged on topics such as oncotic pressure regulation by albumin, the role of globulins in immunity and transport, and the coagulation cascade initiated by fibrinogen. The quiz covers essential clinical correlations, including dysproteinemias and the diagnostic value of serum protein electrophoresis. Sharpen your knowledge and prepare for your exams with these 25 targeted multiple-choice questions. After submitting your answers, you can review your score and download a PDF of all questions with the correct answers for future revision.

1. Which plasma protein is the most significant contributor to colloid osmotic pressure (oncotic pressure)?

2. The majority of plasma proteins are synthesized in the:

3. Which of the following plasma proteins is NOT synthesized in the liver?

4. A deficiency of ceruloplasmin is characteristic of which genetic disorder?

5. On serum protein electrophoresis, which band is typically the most prominent and migrates fastest towards the anode?

6. Haptoglobin is a plasma protein that functions to:

7. The primary difference between blood plasma and serum is that serum lacks:

8. Which of the following is considered a “negative” acute-phase reactant, meaning its concentration decreases during inflammation?

9. Transferrin is the primary plasma protein responsible for transporting:

10. A “monoclonal spike” or M-protein in the gamma region on electrophoresis is a hallmark of:

11. Alpha-1-antitrypsin deficiency can lead to the early onset of which condition?

12. A patient with severe liver disease would most likely exhibit:

13. In nephrotic syndrome, massive proteinuria (primarily albumin) leads to a characteristic electrophoretic pattern of:

14. Which protein is a precursor to the main structural component of a blood clot?

15. A decreased albumin/globulin (A/G) ratio can be seen in all the following conditions EXCEPT:

16. Transthyretin (prealbumin) is a sensitive indicator of:

17. Immunoglobulins are produced by which type of cells?

18. The function of alpha-fetoprotein (AFP) is clinically significant as a marker for:

19. Which plasma protein plays a crucial role in inhibiting serine proteases like elastase, released by neutrophils?

20. In liver cirrhosis, a common finding on serum protein electrophoresis is:

21. Bence-Jones proteins are monoclonal light chains of immunoglobulins found in the urine of patients with:

22. Edema is a clinical sign of severe hypoalbuminemia because of:

22. Edema is a clinical sign of severe hypoalbuminemia because of:

23. Which of the following proteins binds and transports cortisol in the blood?

24. A polyclonal gammopathy, characterized by a broad, diffuse increase in the gamma region, is typically associated with:

25. Which of these is NOT a primary function of plasma proteins?