Meningococcal & Rabies Vaccines MCQ Quiz | Immunization

Welcome, MBBS students! This quiz is designed to test your knowledge on the crucial topic of Meningococcal and Rabies vaccines, a vital component of the Immunization syllabus. The following 25 multiple-choice questions cover key aspects including vaccine types, schedules for pre- and post-exposure prophylaxis, indications for high-risk populations, and management protocols. This assessment will help you reinforce your understanding of these life-saving immunizations. After completing the quiz, you can submit your answers to see your score and review the correct responses. For your convenience and future study, there is an option to download all the questions along with their correct answers in a PDF format. Good luck!

1. Which type of meningococcal vaccine primarily elicits a T-cell independent immune response, offering short-term protection without inducing immunologic memory?

2. What is the most critical first step in managing a potential rabies exposure from an animal bite?

3. A primary advantage of conjugate meningococcal vaccines (MenACWY) over polysaccharide vaccines (MPSV4) is that they:

4. According to WHO guidelines, a person who has completed a full rabies pre-exposure prophylaxis (PrEP) series in the past suffers a Category III exposure. What is the recommended post-exposure prophylaxis (PEP)?

5. Which of the following patient populations is at the highest risk for invasive meningococcal disease and requires routine MenACWY vaccination?

6. How should Rabies Immunoglobulin (RIG) be administered for maximal efficacy in post-exposure prophylaxis?

7. Serogroup B meningococcal (MenB) vaccines are recommended for which age group, especially those entering college and living in residential housing?

8. A bite from a suspected rabid animal on the hand is classified as what category of exposure by the WHO?

9. For which of the following is vaccination with a quadrivalent (A, C, W, Y) meningococcal vaccine a mandatory requirement for entry?

10. The standard dose for Human Rabies Immunoglobulin (HRIG) is calculated based on body weight. What is the correct dose?

11. A deficiency in which part of the immune system confers the highest risk for recurrent invasive meningococcal disease?

12. If RIG was not administered on day 0 with the first dose of rabies vaccine, it can still be given up to which day?

13. The routine adolescent schedule for MenACWY vaccine consists of a primary dose at what age, with a booster dose at age 16?

14. What is the status of pregnancy in relation to rabies post-exposure prophylaxis?

15. A laboratory worker who is routinely exposed to *Neisseria meningitidis* isolates should receive which meningococcal vaccine(s)?

16. The Essen regimen for rabies PEP involves five intramuscular doses of vaccine administered on which days?

17. Which of the following is a key component of conjugate vaccines that allows for a T-cell dependent immune response?

18. Pre-exposure prophylaxis (PrEP) for rabies is most strongly recommended for which of the following individuals?

19. Which statement is true regarding the co-administration of MenACWY and other vaccines?

20. Modern cell culture rabies vaccines (e.g., HDCV, PCECV) have replaced older nerve tissue vaccines primarily because they:

21. What is the recommended administration site for meningococcal vaccines in adolescents and adults?

22. An unvaccinated individual gets a minor scratch with no visible bleeding from a dog. The dog is a stray and cannot be observed. This is a Category II exposure. What is the appropriate PEP?

23. Which of the following is an absolute contraindication to receiving a MenACWY vaccine?

24. Intradermal rabies vaccination regimens are often used in resource-limited settings because they:

25. Bexsero® and Trumenba® are vaccines specifically developed to protect against which serogroup of *Neisseria meningitidis*?

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