MCQ Quiz: Powders

Powders represent one of the oldest and most fundamental solid dosage forms in pharmacy. For B.Pharm students, a thorough understanding of their properties, classification, and compounding techniques is essential. This knowledge is crucial for both traditional extemporaneous preparation and modern industrial applications. This quiz covers the key characteristics of various powders, including effervescent, hygroscopic, and eutectic mixtures, along with important techniques like geometric dilution.


  1. Which of the following is a primary advantage of powders as a dosage form?
    • Accurate dosing for the patient
    • Good stability for all drugs
    • Rapid onset of action due to a large surface area
    • Pleasant taste
    Answer: Rapid onset of action due to a large surface area
  2. A powder that absorbs moisture from the air to the extent that it liquefies is known as:
    • Hygroscopic
    • Efflorescent
    • Deliquescent
    • Eutectic
    Answer: Deliquescent
  3. The technique used to ensure the uniform mixing of a small quantity of a potent drug with a large quantity of a diluent is called:
    • Spatulation
    • Trituration
    • Geometric dilution
    • Levigation
    Answer: Geometric dilution
  4. Effervescent powders produce gas upon contact with water due to a reaction between a weak acid and a:
    • Weak base
    • Strong acid
    • Carbonate or bicarbonate base
    • Salt
    Answer: Carbonate or bicarbonate base
  5. A powder containing water of hydration that may be released when the powder is stored in an environment of low humidity is:
    • Hygroscopic
    • Efflorescent
    • Deliquescent
    • Eutectic
    Answer: Efflorescent
  6. Dusting powders are intended for:
    • Oral administration
    • External application to the skin
    • Parenteral use
    • Inhalation
    Answer: External application to the skin
  7. A mixture of two or more solid substances that becomes liquid upon mixing at room temperature is a(n):
    • Hygroscopic mixture
    • Efflorescent mixture
    • Eutectic mixture
    • Effervescent mixture
    Answer: Eutectic mixture
  8. Which of the following is a major disadvantage of bulk powders?
    • Inaccuracy of the dose
    • Slow drug dissolution
    • High manufacturing cost
    • Difficult to swallow
    Answer: Inaccuracy of the dose
  9. A powder that contains only one chemical ingredient is classified as a:
    • Compound powder
    • Simple powder
    • Bulk powder
    • Divided powder
    Answer: Simple powder
  10. What is the gas liberated from effervescent powders?
    • Oxygen
    • Hydrogen
    • Carbon dioxide
    • Nitrogen
    Answer: Carbon dioxide
  11. To handle a eutectic mixture, a pharmacist can mix each component separately with a(n) ______ before mixing them together.
    • Lubricant
    • Adsorbent powder
    • Solvent
    • Binder
    Answer: Adsorbent powder
  12. Powders that are individually wrapped for the patient are known as:
    • Bulk powders
    • Dusting powders
    • Divided powders
    • Effervescent powders
    Answer: Divided powders
  13. Which of the following must be sterilized if it is to be applied to open wounds?
    • Oral powders
    • Surgical dusting powders
    • Effervescent granules
    • Insufflations
    Answer: Surgical dusting powders
  14. A powder that readily absorbs moisture from the air but does not liquefy is best described as:
    • Efflorescent
    • Hygroscopic
    • Eutectic
    • Anhydrous
    Answer: Hygroscopic
  15. The process of grinding a powder in a mortar with a pestle is called:
    • Spatulation
    • Trituration
    • Sifting
    • Tumbling
    Answer: Trituration
  16. A common acidic ingredient in effervescent formulations is:
    • Sodium bicarbonate
    • Citric acid
    • Calcium carbonate
    • Magnesium oxide
    Answer: Citric acid
  17. Which of the following is a key requirement for a good dusting powder?
    • It must be very coarse.
    • It must be free-flowing and non-irritating.
    • It must be highly soluble.
    • It must be a eutectic mixture.
    Answer: It must be free-flowing and non-irritating.
  18. A powder containing two or more substances that have been mixed together is a:
    • Simple powder
    • Compound powder
    • Atomic powder
    • Monograph powder
    Answer: Compound powder
  19. The primary reason for packing hygroscopic powders in airtight containers is to prevent:
    • Loss of potency
    • Moisture absorption
    • Color change
    • Reaction with the container
    Answer: Moisture absorption
  20. Menthol and camphor are classic examples of substances that form a:
    • Hygroscopic mixture
    • Eutectic mixture
    • Efflorescent powder
    • Effervescent mixture
    Answer: Eutectic mixture
  21. In the first step of geometric dilution, the potent drug is mixed with:
    • The entire amount of diluent
    • An approximately equal volume of diluent
    • A small amount of solvent
    • A lubricant
    Answer: An approximately equal volume of diluent
  22. The main purpose of effervescence in a dosage form is to:
    • Improve the drug’s stability
    • Mask the unpleasant taste of the drug
    • Increase the particle size
    • Provide a local anesthetic effect
    Answer: Mask the unpleasant taste of the drug
  23. Which excipient would be suitable for managing an efflorescent powder?
    • Using an anhydrous form of the drug
    • Adding a wetting agent
    • Storing in a high-humidity environment
    • Using a larger particle size
    Answer: Using an anhydrous form of the drug
  24. Divided powders are a way to overcome which disadvantage of bulk powders?
    • Poor stability
    • Unpleasant taste
    • Inaccurate dosing
    • Slow dissolution
    Answer: Inaccurate dosing
  25. Finely divided powders intended for insufflation are administered into the:
    • Skin
    • Stomach
    • Bloodstream
    • Body cavities (e.g., ear, nose)
    Answer: Body cavities (e.g., ear, nose)
  26. Which of the following is a common basic ingredient in effervescent powders?
    • Tartaric acid
    • Citric acid
    • Sodium bicarbonate
    • Aspirin
    Answer: Sodium bicarbonate
  27. The process of mixing powders by passing them through a sieve is known as:
    • Trituration
    • Spatulation
    • Sifting
    • Tumbling
    Answer: Sifting
  28. Kaolin and light magnesium carbonate are examples of substances used to:
    • Make a mixture effervescent
    • Act as adsorbents for eutectic mixtures
    • Increase the solubility of powders
    • Color the powder
    Answer: Act as adsorbents for eutectic mixtures
  29. Which problem can occur if an efflorescent powder is not handled correctly?
    • It will absorb water from the air.
    • It will release its water of hydration, potentially making the powder damp.
    • It will form a liquid with other solids.
    • It will produce gas when water is added.
    Answer: It will release its water of hydration, potentially making the powder damp.
  30. What is the simplest method of mixing small amounts of powders?
    • Trituration
    • Spatulation
    • Geometric dilution
    • Sifting
    Answer: Spatulation
  31. Compared to tablets or capsules, a therapeutic effect from a powder is generally:
    • Slower
    • Faster
    • The same
    • Delayed by several hours
    Answer: Faster
  32. A common diluent used in geometric dilution is:
    • Water
    • Alcohol
    • Lactose
    • Talc
    Answer: Lactose
  33. Why must effervescent granules be protected from moisture during storage?
    • To prevent a premature effervescent reaction
    • To prevent the growth of mold
    • To prevent the powder from becoming hygroscopic
    • To prevent the powder from dissolving
    Answer: To prevent a premature effervescent reaction
  34. Which type of powder is generally not intended for oral use?
    • Bulk powders for antacids
    • Divided powders in sachets
    • Dusting powders
    • Effervescent powders
    Answer: Dusting powders
  35. The particle size of a powder can influence its:
    • Dissolution rate
    • Flow properties
    • Bioavailability
    • All of the above
    Answer: All of the above
  36. The angle of repose is a property used to measure the:
    • Particle size of a powder
    • Solubility of a powder
    • Flow characteristics of a powder
    • Moisture content of a powder
    Answer: Flow characteristics of a powder
  37. Talc is often used in dusting powders as a:
    • Medicated agent
    • Lubricant and protective agent
    • Coloring agent
    • Binding agent
    Answer: Lubricant and protective agent
  38. The final step in geometric dilution involves:
    • Adding the most potent ingredient first
    • Mixing all ingredients at once
    • Adding the remaining diluent and mixing thoroughly
    • Sifting the mixture through a fine mesh
    Answer: Adding the remaining diluent and mixing thoroughly
  39. Which of the following is an example of an official compound powder in some pharmacopoeias?
    • Compound Sodium Chloride Powder
    • Compound Aspirin Powder
    • Compound Paracetamol Powder
    • Compound Ranitidine Powder
    Answer: Compound Sodium Chloride Powder
  40. The main disadvantage of hygroscopic and deliquescent powders is related to their:
    • High cost
    • Poor therapeutic effect
    • Physical instability due to moisture
    • Bitter taste
    Answer: Physical instability due to moisture
  41. Why is a combination of citric acid and tartaric acid often used in effervescent powders?
    • To prevent the mixture from becoming sticky
    • To provide different rates of dissolution and effervescence
    • To improve the color
    • To reduce the cost
    Answer: To provide different rates of dissolution and effervescence
  42. The term “bulk” powder implies that:
    • The dose is measured by the patient using a device like a teaspoon.
    • The powder is very dense.
    • The powder is individually wrapped.
    • The powder is for external use only.
    Answer: The dose is measured by the patient using a device like a teaspoon.
  43. Which statement is true regarding eutectic mixtures?
    • They are a type of effervescent powder.
    • The melting point of the mixture is lower than any of its individual components.
    • They release water upon exposure to air.
    • They are desirable for improving powder stability.
    Answer: The melting point of the mixture is lower than any of its individual components.
  44. An example of a drug that is efflorescent is:
    • Caffeine
    • Sodium sulfate decahydrate
    • Calcium chloride
    • Camphor
    Answer: Sodium sulfate decahydrate
  45. What is the primary reason for granulating effervescent powders?
    • To increase the particle size and control the rate of reaction
    • To make them less potent
    • To make them easier to dissolve instantly
    • To change their color
    Answer: To increase the particle size and control the rate of reaction
  46. Which of the following would require careful handling in a dry environment?
    • Efflorescent powders
    • Hygroscopic powders
    • Eutectic mixtures
    • Dusting powders
    Answer: Hygroscopic powders
  47. The primary purpose of divided powders (chartulae) is to:
    • Provide a large amount of medication
    • Provide a single, accurate dose of medication
    • Be used externally
    • Be dissolved to create an effervescent drink
    Answer: Provide a single, accurate dose of medication
  48. A powder’s “flowability” is an important property in the manufacturing of:
    • Solutions
    • Tablets and capsules
    • Ointments
    • Syrups
    Answer: Tablets and capsules
  49. Which of the following is NOT a method for mixing powders?
    • Trituration
    • Spatulation
    • Tumbling
    • Sublimation
    Answer: Sublimation
  50. The choice of paper for wrapping divided powders depends on the properties of the drug. For hygroscopic drugs, one would use:
    • Simple bond paper
    • Vegetable parchment paper
    • Waxed paper
    • Glassine paper
    Answer: Waxed paper

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