MCQ Quiz: General Methods of Preparation of Inorganic

Understanding the general methods used to prepare inorganic pharmaceuticals is a core competency for B.Pharm students. These fundamental chemical processes, from simple neutralization to complex redox reactions, are the foundation of how many essential medicinal agents are synthesized. This quiz covers the key principles behind these preparation methods, which are critical for ensuring the purity, quality, and identity of inorganic drugs and excipients.


  1. The reaction between an acid and a base to form a salt and water is known as:
    • Oxidation
    • Reduction
    • Neutralization
    • Precipitation
    Answer: Neutralization
  2. Which method is commonly used to prepare insoluble salts from two soluble salt solutions?
    • Neutralization
    • Double decomposition (Precipitation)
    • Thermal decomposition
    • Direct combination
    Answer: Double decomposition (Precipitation)
  3. The preparation of Magnesium Hydroxide from Magnesium Sulphate and Sodium Hydroxide is an example of:
    • A redox reaction
    • A precipitation reaction
    • A neutralization reaction
    • Thermal decomposition
    Answer: A precipitation reaction
  4. Heating a substance to a high temperature to cause its decomposition is known as:
    • Sublimation
    • Calcination
    • Neutralization
    • Hydrolysis
    Answer: Calcination
  5. The preparation of Ferrous Sulphate by reacting iron with dilute sulphuric acid is an example of which type of reaction?
    • Neutralization
    • Precipitation
    • Displacement
    • Combustion
    Answer: Displacement
  6. Which general method is most suitable for the preparation of an antacid like Aluminum Hydroxide Gel?
    • Thermal decomposition
    • Neutralization of a weak base
    • Precipitation from a soluble aluminum salt
    • Direct combination of elements
    Answer: Precipitation from a soluble aluminum salt
  7. The synthesis of a compound directly from its constituent elements is called:
    • Decomposition
    • Direct combination
    • Displacement
    • Neutralization
    Answer: Direct combination
  8. A reaction that involves a change in the oxidation state of the reacting species is a(n):
    • Acid-base reaction
    • Precipitation reaction
    • Redox reaction
    • Isomerization reaction
    Answer: Redox reaction
  9. The preparation of Boric Acid from borax involves treating a concentrated solution of borax with:
    • A strong base
    • A strong acid like HCl or H₂SO₄
    • An oxidizing agent
    • A reducing agent
    Answer: A strong acid like HCl or H₂SO₄
  10. Which method would be used to prepare Zinc Oxide from Zinc Carbonate?
    • Neutralization
    • Precipitation
    • Thermal decomposition
    • Hydrolysis
    Answer: Thermal decomposition
  11. The preparation of an ammonium salt like Ammonium Chloride often involves the direct neutralization of:
    • Ammonia solution with hydrochloric acid
    • Ammonium sulphate with sodium chloride
    • Nitrogen with chlorine and hydrogen
    • Ammonia gas with chlorine gas
    Answer: Ammonia solution with hydrochloric acid
  12. Potash Alum (Potassium Aluminum Sulphate) is a double salt prepared by:
    • Mixing hot, equimolar solutions of potassium sulphate and aluminum sulphate and then crystallizing.
    • Directly combining potassium, aluminum, and sulphur.
    • Precipitating it from a solution of aluminum chloride.
    • Neutralizing potassium hydroxide with sulphuric acid.
    Answer: Mixing hot, equimolar solutions of potassium sulphate and aluminum sulphate and then crystallizing.
  13. An oxidizing agent is a substance that ______ in a chemical reaction.
    • loses electrons
    • gains electrons
    • loses protons
    • gains protons
    Answer: gains electrons
  14. The preparation of an insoluble salt like BaSO₄ is a classic example of:
    • Neutralization
    • Precipitation
    • Calcination
    • Redox reaction
    Answer: Precipitation
  15. The reaction Fe + H₂SO₄ → FeSO₄ + H₂ is used to prepare Ferrous Sulphate. In this reaction, iron is:
    • Oxidized
    • Reduced
    • Precipitated
    • Neutralized
    Answer: Oxidized
  16. Which of the following is NOT considered a general method of preparation for inorganic salts?
    • Neutralization
    • Polymerization
    • Precipitation
    • Displacement
    Answer: Polymerization
  17. To prepare a soluble salt of a metal that is more reactive than hydrogen, one can react the metal directly with:
    • Water
    • An acid
    • A base
    • Another salt solution
    Answer: An acid
  18. The preparation of Chlorinated Lime involves the reaction of:
    • Chlorine gas with slaked lime
    • Calcium chloride with lime water
    • Hydrochloric acid with lime
    • Chlorine with limestone
    Answer: Chlorine gas with slaked lime
  19. The process of purification of a prepared inorganic salt by dissolving it in a suitable solvent and then crystallizing it out is called:
    • Distillation
    • Sublimation
    • Recrystallization
    • Filtration
    Answer: Recrystallization
  20. Which preparation method relies on the difference in solubility of the product and reactants?
    • Neutralization
    • Direct combination
    • Precipitation
    • Thermal decomposition
    Answer: Precipitation
  21. The synthesis of Sodium Bicarbonate from Sodium Carbonate involves:
    • Heating sodium carbonate
    • Passing carbon dioxide through a saturated solution of sodium carbonate
    • Reacting sodium carbonate with a strong acid
    • Oxidizing sodium carbonate
    Answer: Passing carbon dioxide through a saturated solution of sodium carbonate
  22. A reducing agent is a substance that ______ in a chemical reaction.
    • gains electrons
    • loses electrons
    • gains protons
    • loses protons
    Answer: loses electrons
  23. The preparation of Potassium Iodide can be achieved by reacting iodine with:
    • Potassium metal
    • Potassium chloride
    • Potassium hydroxide solution
    • Potassium sulphate
    Answer: Potassium hydroxide solution
  24. Which method is suitable for preparing a soluble salt from an insoluble base (like CuO)?
    • Reacting the insoluble base with a suitable acid
    • Reacting the insoluble base with another base
    • Heating the insoluble base
    • Precipitating it from a solution
    Answer: Reacting the insoluble base with a suitable acid
  25. The formation of Hydrogen Peroxide involves treating Barium Peroxide with:
    • Water
    • A strong acid like sulphuric or phosphoric acid
    • A strong base
    • Hydrogen gas
    Answer: A strong acid like sulphuric or phosphoric acid
  26. Which of the following is a key consideration in the precipitation method?
    • The precipitate should be highly soluble.
    • The precipitate should be easily filterable and pure.
    • The reaction should be very slow.
    • The reactants should be insoluble.
    Answer: The precipitate should be easily filterable and pure.
  27. The reaction 2NaOH + H₂SO₄ → Na₂SO₄ + 2H₂O is a:
    • Precipitation reaction
    • Neutralization reaction
    • Redox reaction
    • Displacement reaction
    Answer: Neutralization reaction
  28. The preparation of Potassium Permanganate involves the ______ of manganese dioxide.
    • reduction
    • oxidation
    • neutralization
    • hydrolysis
    Answer: oxidation
  29. Which of the following would be prepared by a method involving redox principles?
    • Sodium Chloride
    • Ferrous Sulphate
    • Calcium Carbonate
    • Magnesium Hydroxide
    Answer: Ferrous Sulphate
  30. The process of obtaining a pure solid from a solution by cooling or evaporation is:
    • Filtration
    • Decantation
    • Crystallization
    • Sublimation
    Answer: Crystallization
  31. Which compound is often prepared by reacting a metal carbonate with an acid?
    • A metal oxide
    • A metal hydroxide
    • A metal salt, water, and carbon dioxide
    • A pure metal
    Answer: A metal salt, water, and carbon dioxide
  32. The reaction Zn + CuSO₄ → ZnSO₄ + Cu is a:
    • Neutralization reaction
    • Precipitation reaction
    • Displacement reaction
    • Decomposition reaction
    Answer: Displacement reaction
  33. The final step in many preparation methods to obtain a pure, dry product involves:
    • Filtration and drying
    • Titration
    • Sublimation
    • Neutralization
    Answer: Filtration and drying
  34. To prepare Copper Sulphate from Copper Carbonate, you would react it with:
    • Hydrochloric acid
    • Nitric acid
    • Sulphuric acid
    • Acetic acid
    Answer: Sulphuric acid
  35. The method used must ensure that the final product meets the purity standards of the:
    • Manufacturer
    • Prescriber
    • Pharmacopoeia
    • Patient
    Answer: Pharmacopoeia
  36. Which method is NOT suitable for preparing Sodium Chloride?
    • Neutralizing HCl with NaOH
    • Reacting sodium metal with chlorine gas
    • Reacting sodium carbonate with HCl
    • Precipitating it from two soluble salts
    Answer: Precipitating it from two soluble salts
  37. The synthesis of Kaolin (hydrated aluminum silicate) is not a simple laboratory method but involves:
    • Purification of the naturally occurring mineral
    • A high-temperature fusion reaction
    • A neutralization reaction
    • A redox reaction
    Answer: Purification of the naturally occurring mineral
  38. The preparation of Iodine from crude iodine often involves the process of:
    • Distillation
    • Crystallization
    • Sublimation
    • Filtration
    Answer: Sublimation
  39. Which general method is used to prepare the antacid Magnesium Carbonate?
    • Precipitation by mixing solutions of magnesium sulphate and sodium carbonate
    • Neutralizing magnesium hydroxide with carbonic acid
    • Heating magnesium metal
    • Reacting magnesium with carbon dioxide
    Answer: Precipitation by mixing solutions of magnesium sulphate and sodium carbonate
  40. The choice of preparation method for an inorganic pharmaceutical depends on:
    • The starting materials available
    • The desired purity of the product
    • The solubility of the product
    • All of the above
    Answer: All of the above
  41. The reaction AgNO₃(aq) + NaCl(aq) → AgCl(s) + NaNO₃(aq) is a classic example of:
    • Neutralization
    • Redox
    • Double decomposition
    • Displacement
    Answer: Double decomposition
  42. Many haematinics, like Ferrous Gluconate, are prepared by reacting:
    • An iron oxide with the corresponding acid
    • A freshly prepared ferrous salt with the corresponding acid or its salt
    • Iron metal with the corresponding acid
    • A ferric salt with a reducing agent
    Answer: A freshly prepared ferrous salt with the corresponding acid or its salt
  43. The key to a successful neutralization reaction is the accurate determination of the:
    • Equivalence point
    • Melting point
    • Boiling point
    • Solubility
    Answer: Equivalence point
  44. Which of these compounds can be prepared by direct combination of a metal and a non-metal?
    • Ferric Chloride (FeCl₃)
    • Sodium Chloride (NaCl)
    • Magnesium Oxide (MgO)
    • All of the above
    Answer: All of the above
  45. The preparation of Sodium Thiosulphate involves boiling a solution of sodium sulphite with:
    • Oxygen
    • Sulphur
    • Hydrogen
    • Chlorine
    Answer: Sulphur
  46. In many preparations, an intermediate product is a ______ which is then converted to the final product.
    • Gas
    • Precipitate
    • Liquid
    • Soluble complex
    Answer: Precipitate
  47. The method of hydrolysis is used to prepare some compounds. It involves a reaction with:
    • Acid
    • Base
    • Water
    • Air
    Answer: Water
  48. Which of the following is an important factor for controlling particle size in a precipitation reaction?
    • Temperature
    • Concentration of reactants
    • Rate of mixing
    • All of the above
    Answer: All of the above
  49. The preparation of the expectorant Ammonium Chloride can be classified as a(n) ______ reaction.
    • precipitation
    • redox
    • neutralization
    • displacement
    Answer: neutralization
  50. The purpose of washing a precipitate during its preparation is to:
    • Dissolve the precipitate
    • Remove soluble impurities
    • Convert it to its final form
    • Increase its particle size
    Answer: Remove soluble impurities

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