MCQ Quiz: Body fluids

A thorough understanding of body fluids, including blood and lymph, is paramount for B.Pharm students. These fluids are the body’s primary transport medium, crucial for drug distribution, immune responses, and maintaining homeostasis. This quiz covers the composition and functions of blood, the processes of hemopoiesis and coagulation, and the fundamentals of the lymphatic system. Mastering these topics provides the foundation for comprehending pharmacokinetics, hematological drugs, and various diagnostic parameters.


  1. Which of the following is the most abundant component of blood plasma?
    • Proteins
    • Water
    • Electrolytes
    • Gases
    Answer: Water
  2. The process of formation of blood cells is known as:
    • Hemolysis
    • Hemostasis
    • Hemopoiesis
    • Hematocrit
    Answer: Hemopoiesis
  3. Which protein is essential for the blood coagulation process?
    • Albumin
    • Globulin
    • Fibrinogen
    • Hemoglobin
    Answer: Fibrinogen
  4. A person with blood group O can receive blood from which blood group?
    • A
    • B
    • AB
    • O
    Answer: O
  5. Which formed element of the blood is responsible for oxygen transport?
    • Leukocytes
    • Thrombocytes
    • Erythrocytes
    • Basophils
    Answer: Erythrocytes
  6. What is the primary function of the lymphatic system?
    • Transporting oxygen
    • Returning interstitial fluid to the blood
    • Producing hormones
    • Regulating body temperature
    Answer: Returning interstitial fluid to the blood
  7. A deficiency in hemoglobin or red blood cells can lead to a condition called:
    • Leukemia
    • Anemia
    • Thrombocytopenia
    • Polycythemia
    Answer: Anemia
  8. Which molecule within red blood cells binds to oxygen?
    • Albumin
    • Fibrin
    • Heme group of hemoglobin
    • Globin chain
    Answer: Heme group of hemoglobin
  9. The final step in blood coagulation is the conversion of:
    • Prothrombin to thrombin
    • Fibrinogen to fibrin
    • Plasminogen to plasmin
    • Thrombin to fibrinogen
    Answer: Fibrinogen to fibrin
  10. The Rh factor is a type of ______ found on the surface of red blood cells.
    • Antibody
    • Antigen
    • Enzyme
    • Hormone
    Answer: Antigen
  11. Which of the following are the most numerous leukocytes in the blood?
    • Lymphocytes
    • Eosinophils
    • Basophils
    • Neutrophils
    Answer: Neutrophils
  12. The fluid component of blood after the removal of clotting factors is called:
    • Plasma
    • Serum
    • Lymph
    • Interstitial fluid
    Answer: Serum
  13. Platelets are fragments of which large cell?
    • Erythroblast
    • Myeloblast
    • Megakaryocyte
    • Lymphoblast
    Answer: Megakaryocyte
  14. What is the main function of albumin in blood plasma?
    • Blood clotting
    • Immune defense
    • Maintaining osmotic pressure
    • Transporting hormones
    Answer: Maintaining osmotic pressure
  15. A person with blood type AB is known as the universal recipient because they:
    • Have no antigens on their RBCs
    • Have no antibodies in their plasma
    • Have both anti-A and anti-B antibodies
    • Can only receive type O blood
    Answer: Have no antibodies in their plasma
  16. Which lymphatic organ is responsible for filtering blood and removing old red blood cells?
    • Thymus
    • Lymph node
    • Spleen
    • Tonsils
    Answer: Spleen
  17. The stoppage of bleeding is referred to as:
    • Coagulation
    • Hemopoiesis
    • Agglutination
    • Hemostasis
    Answer: Hemostasis
  18. Which leukocytes are primarily involved in the immune response against parasites and in allergic reactions?
    • Neutrophils
    • Basophils
    • Eosinophils
    • Monocytes
    Answer: Eosinophils
  19. What is the term for the clumping of red blood cells during a mismatched blood transfusion?
    • Coagulation
    • Hemolysis
    • Agglutination
    • Crenation
    Answer: Agglutination
  20. Lymphatic vessels are similar in structure to:
    • Arteries
    • Veins
    • Capillaries
    • Arterioles
    Answer: Veins
  21. Formation of a platelet plug is the first step in:
    • Hemopoiesis
    • Hemostasis
    • Erythropoiesis
    • Inflammation
    Answer: Hemostasis
  22. Which blood cells differentiate into macrophages in the tissues?
    • Neutrophils
    • Lymphocytes
    • Basophils
    • Monocytes
    Answer: Monocytes
  23. The main function of red blood cells is to transport:
    • Nutrients
    • Hormones
    • Oxygen and carbon dioxide
    • Waste products
    Answer: Oxygen and carbon dioxide
  24. The fluid found in the spaces between cells is called:
    • Plasma
    • Lymph
    • Intracellular fluid
    • Interstitial fluid
    Answer: Interstitial fluid
  25. The Reticuloendothelial System is primarily involved in:
    • Nerve impulse transmission
    • Phagocytosis of cellular debris and pathogens
    • Muscle contraction
    • Hormone production
    Answer: Phagocytosis of cellular debris and pathogens
  26. Which of the following is a primary lymphatic organ?
    • Spleen
    • Lymph node
    • Red bone marrow
    • Tonsil
    Answer: Red bone marrow
  27. A blood clot that is moving through the bloodstream is called a(n):
    • Thrombus
    • Embolus
    • Plaque
    • Scab
    Answer: Embolus
  28. Which of the following is NOT a component of lymph?
    • Water
    • Red blood cells
    • Lymphocytes
    • Dissolved solutes
    Answer: Red blood cells
  29. A person with type B blood has which type of antibodies in their plasma?
    • Anti-A
    • Anti-B
    • Both Anti-A and Anti-B
    • Neither Anti-A nor Anti-B
    Answer: Anti-A
  30. What is the average lifespan of a mature red blood cell?
    • 30 days
    • 60 days
    • 120 days
    • 365 days
    Answer: 120 days
  31. The circulation of lymph is primarily driven by:
    • The pumping action of the heart
    • High pressure in lymphatic capillaries
    • Contraction of skeletal muscles and respiratory movements
    • The pull of gravity
    Answer: Contraction of skeletal muscles and respiratory movements
  32. Which leukocytes release histamine and heparin to promote inflammation?
    • Eosinophils
    • Neutrophils
    • Monocytes
    • Basophils
    Answer: Basophils
  33. The formation of hemoglobin requires which mineral?
    • Calcium
    • Iron
    • Sodium
    • Potassium
    Answer: Iron
  34. Lymph from the majority of the body drains into the:
    • Right lymphatic duct
    • Thoracic duct
    • Cisterna chyli
    • Subclavian vein directly
    Answer: Thoracic duct
  35. The term for a low platelet count is:
    • Leukemia
    • Anemia
    • Thrombocytopenia
    • Leukocytosis
    Answer: Thrombocytopenia
  36. Which plasma proteins are primarily involved in the immune response?
    • Albumins
    • Fibrinogens
    • Globulins
    • Prothrombins
    Answer: Globulins
  37. Hemolytic disease of the newborn can occur if:
    • An Rh- mother is carrying an Rh+ fetus
    • An Rh+ mother is carrying an Rh- fetus
    • A mother with type O blood has a fetus with type A blood
    • A mother with type AB blood has a fetus with type O blood
    Answer: An Rh- mother is carrying an Rh+ fetus
  38. Which of the following is considered a formed element of blood?
    • Plasma
    • Albumin
    • Platelets
    • Water
    Answer: Platelets
  39. Lymph nodes function to:
    • Produce red blood cells
    • Filter lymph and house immune cells
    • Secrete hormones
    • Regulate blood pressure
    Answer: Filter lymph and house immune cells
  40. The intrinsic and extrinsic pathways of coagulation merge to form the common pathway, which begins with the activation of:
    • Thrombin
    • Fibrin
    • Factor X
    • Prothrombin
    Answer: Factor X
  41. Which body fluid is considered intracellular fluid?
    • Plasma
    • Lymph
    • Cytosol
    • Interstitial fluid
    Answer: Cytosol
  42. T-lymphocytes and B-lymphocytes are the major cells of the:
    • Coagulation cascade
    • Adaptive immune system
    • Oxygen transport system
    • Inflammatory response
    Answer: Adaptive immune system
  43. A stationary blood clot formed within a blood vessel is a(n):
    • Embolus
    • Thrombus
    • Hematoma
    • Agglutinin
    Answer: Thrombus
  44. What percentage of blood volume is typically composed of plasma?
    • 10%
    • 25%
    • 55%
    • 90%
    Answer: 55%
  45. The large lymphatic vessel that collects lymph from the right upper side of the body is the:
    • Thoracic duct
    • Right lymphatic duct
    • Cisterna chyli
    • Right subclavian vein
    Answer: Right lymphatic duct
  46. All formed elements of the blood are ultimately derived from which cells?
    • Myeloid stem cells
    • Lymphoid stem cells
    • Hemocytoblasts (hematopoietic stem cells)
    • Proerythroblasts
    Answer: Hemocytoblasts (hematopoietic stem cells)
  47. A transfusion reaction is a result of:
    • An interaction between donor antibodies and recipient antigens
    • An interaction between donor antigens and recipient antibodies
    • A failure of the blood to clot
    • An allergic reaction to plasma proteins
    Answer: An interaction between donor antigens and recipient antibodies
  48. Which organ is the site of T-cell maturation?
    • Spleen
    • Thymus
    • Red bone marrow
    • Lymph node
    Answer: Thymus
  49. The most common blood type among humans is:
    • A
    • B
    • AB
    • O
    Answer: O
  50. The primary purpose of blood grouping and cross-matching before a transfusion is to prevent:
    • Blood coagulation
    • Infection transmission
    • Agglutination and hemolysis
    • A decrease in blood volume
    Answer: Agglutination and hemolysis

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