Management of Neonatal Jaundice MCQ Quiz | Neonatology Skills

Welcome to the Neonatal Jaundice Management Quiz for MBBS students. This quiz is designed to test your understanding of the clinical assessment, investigation, and treatment protocols for jaundice in newborns, a critical skill in neonatology. You will be presented with 25 multiple-choice questions covering topics from phototherapy and exchange transfusions to the nuances of breastfeeding vs. breast milk jaundice. After submitting your answers, your score will be displayed, and the correct answers will be highlighted for your review. This interactive format will help you consolidate your knowledge and prepare for your examinations. You can also download a PDF copy of all questions and their correct answers for offline study by clicking the “Download Answers” button after completing the quiz.

1. Phototherapy acts to reduce serum bilirubin primarily by converting it into which water-soluble photoisomer that can be excreted without conjugation?

2. According to the American Academy of Pediatrics (AAP) guidelines, at what Total Serum Bilirubin (TSB) level should phototherapy be initiated in a high-risk term infant (35-37 weeks) at 48 hours of life?

3. A 4-day-old term neonate with ABO incompatibility has a TSB of 24 mg/dL despite 6 hours of intensive phototherapy. The next most appropriate step is:

4. Which of the following is a characteristic feature of ‘breast milk jaundice’ as opposed to ‘breastfeeding jaundice’?

5. “Bronze baby syndrome” is a potential side effect of phototherapy in neonates with:

6. In a neonate with hemolytic disease of the newborn due to Rh isoimmunization, which investigation is crucial for diagnosis?

7. The optimal wavelength of light for effective phototherapy is in which range?

8. Which of the following conditions is a contraindication for phototherapy?

9. What is the primary mechanism of action of IVIG in the management of isoimmune hemolytic jaundice?

10. Jaundice appearing within the first 24 hours of life is:

11. The term ‘kernicterus’ refers to:

12. To maximize the efficacy of phototherapy, which factor is most important?

13. Which of the following laboratory findings would suggest a cholestatic (conjugated) hyperbilirubinemia?

14. A major risk associated with a double volume exchange transfusion is:

15. Gilbert syndrome is a common inherited cause of mild unconjugated hyperbilirubinemia due to a partial deficiency of which enzyme?

16. The Bhutani nomogram is used to:

17. Which maternal blood type, in combination with an infant’s blood type, poses the highest risk for ABO hemolytic disease of the newborn?

18. To ensure eye safety during phototherapy, the standard practice is to:

19. In Crigler-Najjar syndrome Type I, the unconjugated hyperbilirubinemia is severe and life-threatening due to:

20. What is the main principle behind ‘double volume’ exchange transfusion?

21. An infant with G6PD deficiency is at higher risk for severe jaundice, especially when exposed to:

22. Which of these is NOT a recognized side effect of phototherapy?

23. When evaluating a jaundiced neonate, a “rebound bilirubin” level is typically checked after:

24. A term infant with jaundice has clay-colored stools and dark urine. This presentation is highly suggestive of:

25. The Bilirubin/Albumin (B/A) ratio is used as an additional factor in determining the need for exchange transfusion because: