Malaria MCQ Quiz | Infectious Diseases

Welcome, MBBS students! This quiz is designed to test your understanding of Malaria, a critical topic in Infectious Diseases. Covering its pathophysiology, clinical presentation, diagnosis, and management, these 25 multiple-choice questions will help you consolidate your knowledge for exams. Each question challenges your grasp of key concepts, from the Plasmodium life cycle to the latest treatment protocols. After submitting your answers, you will receive your score and see a detailed breakdown of correct and incorrect responses. For your revision, you can also download a PDF file containing all the questions along with their correct answers. This tool is perfect for self-assessment and focused study. Good luck!

1. Which Plasmodium species is most associated with severe and fatal malaria?

2. The dormant liver stage responsible for relapses in P. vivax and P. ovale infections is called a:

3. The primary vector for malaria transmission to humans is the:

4. The classic malarial paroxysm consists of a cold stage, a hot stage, and a:

5. The gold standard for the diagnosis of malaria is:

6. Which morphological feature is characteristic of Plasmodium falciparum gametocytes on a peripheral blood smear?

7. Cerebral malaria, a severe complication, is most commonly caused by which species?

8. What is the first-line treatment for uncomplicated Plasmodium falciparum malaria in most endemic regions?

9. Which drug is essential for the radical cure of P. vivax and P. ovale malaria by targeting hypnozoites?

10. Before administering primaquine, it is crucial to test for which enzyme deficiency to avoid hemolysis?

11. The sequestration of parasitized red blood cells in the microvasculature of vital organs is a key pathophysiological feature of:

12. A fever cycle that recurs every 48 hours (on day 1 and day 3) is termed “tertian malaria” and is characteristic of which species?

13. A fever cycle recurring every 72 hours (on day 1 and day 4) is known as “quartan malaria” and is caused by:

14. Rapid Diagnostic Tests (RDTs) for malaria typically detect which of the following?

15. Which of the following is a key criterion for defining severe malaria according to WHO guidelines?

16. Blackwater fever, a complication characterized by massive intravascular hemolysis and hemoglobinuria, is associated with which Plasmodium species?

17. Which of the following is a commonly prescribed chemoprophylactic agent for travelers to malaria-endemic areas?

18. Malaria in pregnancy is associated with an increased risk of all the following EXCEPT:

19. Chronic or repeated malaria infections often lead to a massively enlarged spleen, a condition known as:

20. Resistance of P. falciparum to which older antimalarial drug is now widespread, limiting its use as a monotherapy?

21. The infective stage of the Plasmodium parasite transmitted from the mosquito to the human is the:

22. The stage of the Plasmodium parasite that is ingested by a mosquito from an infected human’s blood is the:

23. “Schüffner’s dots” are fine, eosinophilic granules seen in the cytoplasm of red blood cells infected with which Plasmodium species?

24. What is the recommended drug of choice for the treatment of severe malaria?

25. The most effective method of preventing malaria transmission on a community level involves: