Leishmaniasis MCQ Quiz | PUO & Febrile Illnesses

Welcome to this specialized quiz on Leishmaniasis, a critical topic within Pyrexia of Unknown Origin (PUO) & Febrile Illnesses for MBBS students. This quiz features 25 multiple-choice questions designed to test your understanding of the parasite’s life cycle, clinical manifestations including Visceral, Cutaneous, and Mucocutaneous forms, diagnostic methods, and current treatment protocols. Each question is crafted to reflect the level of detail required for your professional exams. After submitting your answers, you will receive your score and see the correct options highlighted. For your future reference and revision, you can also download a PDF document containing all the questions along with their correct answers. Good luck!

1. What is the primary vector for the transmission of Leishmaniasis?

2. The infective stage of *Leishmania* found in the sandfly’s proboscis is the:

3. Visceral Leishmaniasis is also commonly known as:

4. The form of *Leishmania* found within macrophages of the vertebrate host is the:

5. The gold standard for diagnosing Visceral Leishmaniasis is the demonstration of LD bodies in:

6. A highly sensitive immunochromatographic test for rapid diagnosis of Visceral Leishmaniasis is based on detecting antibodies to:

7. In the Indian subcontinent, what is the current first-line treatment for Visceral Leishmaniasis?

8. Post-Kala-azar Dermal Leishmaniasis (PKDL) typically appears:

9. The typical lesion of Cutaneous Leishmaniasis evolves into:

10. Which form of leishmaniasis causes severe destruction of the nasal and oropharyngeal mucosa?

11. The Montenegro test (Leishmanin skin test) is a type of:

12. How does the Montenegro test typically present in a patient with active Visceral Leishmaniasis?

13. A significant cardiotoxic effect of pentavalent antimonials is:

14. Which oral drug is effective for treating Visceral Leishmaniasis and is particularly important for managing PKDL?

15. In the anthroponotic cycle of *L. donovani* in India, the primary reservoir is:

16. The classic pentad of signs in Visceral Leishmaniasis includes fever, weight loss, hepatosplenomegaly, anemia, and:

17. Which stain is most commonly used to identify Leishman-Donovan (LD) bodies in aspirates?

18. The mechanism of action of Amphotericin B against *Leishmania* involves:

19. “Chiclero’s ulcer,” affecting the ear pinna, is commonly caused by which species?

20. The most common causative species for Mucocutaneous Leishmaniasis in the New World is:

21. Kala-azar is endemic in India, primarily concentrated in which group of states?

22. Napier’s Aldehyde test (formol-gel test) is a non-specific test for Kala-azar that relies on detecting:

23. Miltefosine represented a significant advancement in leishmaniasis treatment because it is:

24. A key strategy for controlling the sandfly vector of leishmaniasis is:

25. Pancytopenia is a common hematological finding in Visceral Leishmaniasis due to: