1. What is the most common causative organism in non-gonococcal bacterial arthritis in adults?
2. Which of the following represents the classic triad of disseminated gonococcal infection (DGI)?
3. A synovial fluid white blood cell (WBC) count above which of the following levels is highly suggestive of septic arthritis?
4. A 25-year-old sexually active female presents with migratory polyarthralgias, tenosynovitis of the wrist, and a few pustular skin lesions on her extremities. The most likely diagnosis is:
5. What is the most important initial diagnostic procedure for a patient with suspected infectious arthritis?
6. Empiric antibiotic therapy for a suspected septic arthritis in an adult without specific risk factors (e.g., IV drug use, immunosuppression) should primarily cover:
7. Phemister’s triad, consisting of juxta-articular osteoporosis, peripheral erosions, and gradual joint space narrowing on X-ray, is characteristic of which type of infectious arthritis?
8. A patient with a prosthetic knee joint presents with chronic, low-grade pain and loosening of the implant 2 years after surgery. What is the most likely causative organism?
9. Which of the following is NOT a common route for joint infection?
10. An intravenous drug user presents with septic arthritis of the sternoclavicular joint. The most likely causative organism is:
11. The definitive diagnosis of septic arthritis is established by:
12. Which viral infection is most commonly associated with a symmetric polyarthritis that can mimic rheumatoid arthritis?
13. A farmer from an endemic area presents with chronic monoarthritis of the knee. Synovial fluid shows a WBC of 20,000 cells/μL with a lymphocytic predominance. Acid-fast bacilli stain is negative. What is the most likely diagnosis?
14. In addition to appropriate antibiotic therapy, which management step is crucial for minimizing joint damage in bacterial arthritis?
15. Lyme arthritis, caused by *Borrelia burgdorferi*, typically presents as:
16. A 60-year-old diabetic patient presents with a hot, swollen, and painful right knee. Arthrocentesis is performed. Which synovial fluid finding is LEAST consistent with septic arthritis?
17. What is the typical recommended duration of intravenous or highly bioavailable oral antibiotic therapy for uncomplicated native joint bacterial arthritis?
18. Which of the following is considered the most significant risk factor for developing septic arthritis?
19. A patient is diagnosed with gonococcal arthritis. What is the recommended first-line antibiotic treatment?
20. Tuberculous arthritis most commonly affects which joints?
21. What is the primary mechanism by which bacteria cause rapid cartilage destruction in septic arthritis?
22. A patient with sickle cell disease presents with septic arthritis. In addition to common pathogens, which organism should be specifically considered and covered?
23. An elderly patient from a nursing home with multiple comorbidities develops septic arthritis of the knee. Empiric antibiotic therapy should provide broad coverage, especially for:
24. Which imaging modality is most sensitive for detecting early osteomyelitis as a complication of septic arthritis?
25. In a patient with suspected septic arthritis, synovial fluid should be sent for all of the following routine tests EXCEPT:
