Drugs for Glaucoma MCQ Quiz | Miscellaneous

Welcome to the Drugs for Glaucoma MCQ Quiz, specifically designed for MBBS students preparing for their pharmacology exams. This quiz covers the essential drug classes used in glaucoma management, including prostaglandin analogues, beta-blockers, alpha-adrenergic agonists, carbonic anhydrase inhibitors, and miotics. You will be tested on their mechanisms of action, key side effects, clinical applications, and contraindications. This comprehensive assessment contains 25 multiple-choice questions to help you evaluate your understanding and identify areas for review. After submitting your answers, you’ll receive your score and see the correct answers highlighted. For your convenience, you can also download all the questions along with their correct answers in a PDF format for offline study. Good luck!

1. What is the primary mechanism of action of prostaglandin analogues like Latanoprost in treating glaucoma?

2. A common and irreversible side effect associated with long-term use of prostaglandin analogues is:

3. How do beta-blockers like Timolol lower intraocular pressure (IOP)?

4. Topical Timolol is contraindicated in a patient with a history of:

5. Which of the following is a cardioselective (beta-1) blocker, making it a safer option for patients with mild respiratory disease?

6. Brimonidine, an alpha-2 adrenergic agonist, has a dual mechanism of action which includes:

7. The mechanism of action for topical carbonic anhydrase inhibitors like Dorzolamide is:

8. Systemic Acetazolamide can lead to which of the following metabolic disturbances?

9. Pilocarpine, a cholinergic agonist, lowers IOP primarily by:

10. A patient reports brow ache and blurred distance vision after starting a new glaucoma drop. Which drug is most likely responsible?

11. In a patient with acute angle-closure glaucoma, which intravenous agent is used to rapidly lower IOP by an osmotic effect?

12. What is generally considered the first-line medical therapy for primary open-angle glaucoma (POAG)?

13. Which glaucoma medication is most likely to cause miosis (pupillary constriction)?

14. A patient using Brimonidine eye drops reports fatigue and dry mouth. These symptoms are due to:

15. Use of Latanoprost may be a concern in patients with a history of:

16. Apraclonidine is an alpha-2 agonist that is often used for:

17. Which non-selective beta-blocker is available as a gel-forming solution for once-daily dosing?

18. A patient with a known sulfa allergy should use which class of glaucoma drugs with caution?

19. Which combination drug provides two different mechanisms for decreasing aqueous humor production?

20. A bitter or metallic taste in the mouth is a commonly reported side effect of which topical glaucoma medication?

21. The phenomenon of tachyphylaxis (rapid loss of efficacy) is most notably associated with which glaucoma drug?

22. Which drug is a Rho kinase inhibitor that increases trabecular meshwork outflow by relaxing the trabecular meshwork cells?

23. Unlike other miotics, which drug is a cholinesterase inhibitor that has a very long duration of action?

24. Which of the following drugs acts by decreasing episcleral venous pressure in addition to its other mechanisms?

25. A patient with glaucoma is also being treated for depression with an MAO inhibitor. Which glaucoma medication should be avoided?