Derivative of a function MCQs With Answer are essential for B.Pharm students who need to master calculus concepts applied to pharmacokinetics, drug release, and rate processes. This concise, SEO-friendly introduction covers core ideas like the derivative as the instantaneous rate of change, rules (power, product, quotient, chain), higher-order derivatives, and real-life applications such as concentration-time profiles, half-life, and dose–response curves. Clear understanding of derivatives helps in modeling drug absorption, elimination, and reaction kinetics, improving problem-solving in pharmaceutics and biopharmaceutics. Now let’s test your knowledge with 50 MCQs on this topic.
Q1. What does the derivative of a function at a point represent?
- The average value of the function near the point
- The instantaneous rate of change of the function at that point
- The area under the curve up to that point
- The maximum value of the function
Correct Answer: The instantaneous rate of change of the function at that point
Q2. If C(t) = C0 e-kt describes drug concentration, what is dC/dt?
- dC/dt = k C0 e-kt
- dC/dt = -k C0 e-kt
- dC/dt = -C0 e-kt
- dC/dt = k e-kt
Correct Answer: dC/dt = -k C0 e-kt
Q3. What is the derivative of f(x)=xn (power rule) for n constant?
- f'(x)=n xn-1
- f'(x)=xn+1/n
- f'(x)=n xn+1
- f'(x)=xn ln n
Correct Answer: f'(x)=n xn-1
Q4. For f(x)=ln(x), what is f'(x)?
- 1/ln(x)
- 1/x
- ln(x)/x
- x
Correct Answer: 1/x
Q5. Which rule is used to differentiate f(x)=u(x)v(x)?
- Chain rule
- Product rule
- Quotient rule
- Power rule
Correct Answer: Product rule
Q6. If f(x)=u(x)/v(x), which formula gives f'(x)?
- (u’v – uv’)/v
- (u’v + uv’)/v2
- (u’v – uv’)/v2
- (u’v + uv’)/v
Correct Answer: (u’v – uv’)/v2
Q7. Find derivative of f(x)=eax where a is constant.
- a eax
- eax/a
- ln(a) eax
- ex
Correct Answer: a eax
Q8. For y = sin(x), y’ equals?
- cos(x)
- -cos(x)
- sin(x)
- -sin(x)
Correct Answer: cos(x)
Q9. Using chain rule, derivative of y = (3x+1)4 is:
- 4(3x+1)3
- 12(3x+1)3
- (3x+1)4·3
- 4(3x+1)4
Correct Answer: 12(3x+1)3
Q10. If concentration follows C(t)=At/(Bt+1), what derivative rule is most directly applied?
- Product rule
- Chain rule
- Quotient rule
- Power rule
Correct Answer: Quotient rule
Q11. The derivative of pH = -log10[H+] with respect to [H+] is:
- -1/[H+]
- -1/(ln10 · [H+])
- 1/(ln10 · [H+])
- 1/[H+]
Correct Answer: -1/(ln10 · [H+])
Q12. If V(t)=Vmax·S/(Km+S) (Michaelis-Menten), dV/dS involves:
- Vmax·(Km+S)/(Km+S)2
- Vmax·Km/(Km+S)2
- Vmax·Km/(Km+S)
- Vmax·(Km)/(S)
Correct Answer: Vmax·Km/(Km+S)2
Q13. What is the derivative of f(x)=arctan(x)?
- 1/(1+x2)
- 1/(1-x2)
- x/(1+x2)
- 1/√(1-x2)
Correct Answer: 1/(1+x2)
Q14. The second derivative f”(x) gives information on:
- Instantaneous rate of change
- Concavity and acceleration
- Average slope over interval
- Value of function
Correct Answer: Concavity and acceleration
Q15. If f'(x0)=0 and f”(x0)<0, x0 is:
- A point of inflection
- Local minimum
- Local maximum
- Not differentiable
Correct Answer: Local maximum
Q16. The derivative of |x| at x=0 is:
- 0
- 1
- -1
- Does not exist
Correct Answer: Does not exist
Q17. For parametric curves x(t), y(t), dy/dx equals:
- dx/dt ÷ dy/dt
- dy/dt · dx/dt
- (dy/dt)/(dx/dt)
- Integral of dy/dt
Correct Answer: (dy/dt)/(dx/dt)
Q18. Differentiate f(x)=ln(ax) where a>0 constant.
- 1/(ax)
- a/(ax)
- 1/x
- ln(a)/x
Correct Answer: 1/x
Q19. If drug amount A(t)=kt, what is dA/dt?
- A(t)/t
- k
- t/k
- 0
Correct Answer: k
Q20. The derivative of tan(x) is:
- sec(x)
- sec2(x)
- cos2(x)
- csc2(x)
Correct Answer: sec2(x)
Q21. Use implicit differentiation: For x2 + y2 = R2, dy/dx =
- -x/y
- -y/x
- x/y
- y/x
Correct Answer: -x/y
Q22. The derivative of f(x)=x·ex is:
- ex + x ex
- x ex
- ex
- xe2x
Correct Answer: ex + x ex
Q23. If C(t)=C0/(1+kt) (simple elimination), dC/dt at t=0 equals:
- -C0 k
- -C0 k/(1+kt)2
- -C0 k at t=0 gives -C0 k
- 0
Correct Answer: -C0 k
Q24. The derivative of f(x)=log10(x) is:
- 1/(x ln 10)
- 1/x
- ln 10 / x
- ln(x)/10
Correct Answer: 1/(x ln 10)
Q25. Which expression equals derivative of inverse function (f-1)'(y)?
- 1/f'(y)
- 1/f'(f-1(y))
- f'(f-1(y))
- -1/f'(f-1(y))
Correct Answer: 1/f'(f-1(y))
Q26. For f(x)=x3-3x, critical points where f’=0 are:
- x=0, x=±1
- x=1 only
- x=0 only
- No real critical points
Correct Answer: x=0, x=±1
Q27. Differentiate f(x)=sin2(x) using chain rule.
- 2 sin(x) cos(x)
- sin(2x)
- cos(2x)
- Both 2 sin(x) cos(x) and sin(2x) are equivalent
Correct Answer: Both 2 sin(x) cos(x) and sin(2x) are equivalent
Q28. If concentration C(t)=C0 e-k t and k increases, instantaneous elimination rate dC/dt at fixed t:
- Decreases in magnitude
- Increases in magnitude (more negative)
- Remains unchanged
- Becomes positive
Correct Answer: Increases in magnitude (more negative)
Q29. The derivative of f(x)=x1/2 is:
- 1/(2√x)
- √x/2
- 1/√x
- x-1/2/2
Correct Answer: 1/(2√x)
Q30. Using logarithmic differentiation, derivative of f(x)=xx is:
- xx(ln x + 1)
- xx·ln x
- xx-1
- ln x
Correct Answer: xx(ln x + 1)
Q31. What is the derivative of f(x)=sec(x)?
- sec(x)tan(x)
- sec(x)cos(x)
- tan(x)
- sec2(x)
Correct Answer: sec(x)tan(x)
Q32. If drug absorption A(t)=t e-t, what is dA/dt?
- e-t(1 – t)
- e-t(1 + t)
- t e-t
- -t e-t
Correct Answer: e-t(1 – t)
Q33. For composite f(g(x)), the chain rule form is:
- f'(g(x)) · g'(x)
- g'(f(x)) · f'(x)
- f(g'(x))
- f'(x) + g'(x)
Correct Answer: f'(g(x)) · g'(x)
Q34. The derivative of inverse sine f(x)=arcsin(x) equals:
- 1/√(1-x2)
- 1/(1-x2)
- 1/√(1+x2)
- 1/(1+x2)
Correct Answer: 1/√(1-x2)
Q35. If velocity v(t)=dx/dt and acceleration a(t)=dv/dt, then a(t) equals:
- d2x/dt
- d x/dt
- d2t/dx
- Integral of v(t)
Correct Answer: d2x/dt
Q36. For f(x)= (2x+1)-2, f'(x) is:
- -4(2x+1)-3
- -2(2x+1)-3
- 4(2x+1)-3
- (2x+1)-1
Correct Answer: -4(2x+1)-3
Q37. If a rate law r=k[A]2, derivative dr/d[A] equals:
- 2k[A]
- k[A]2
- 2k[A]2
- k
Correct Answer: 2k[A]
Q38. Which statement about differentiability implies continuity?
- If f is differentiable at a point, then f is continuous at that point
- If f is continuous at a point, then f is differentiable there
- Differentiability and continuity are unrelated
- Continuity implies differentiability for polynomials only
Correct Answer: If f is differentiable at a point, then f is continuous at that point
Q39. The derivative of f(x)=cos(x) is:
- -sin(x)
- sin(x)
- -cos(x)
- cos(x)
Correct Answer: -sin(x)
Q40. For f(x)=1/x, f'(x) is:
- -1/x2
- 1/x2
- -x
- 0
Correct Answer: -1/x2
Q41. If plasma concentration C(t) has maximum at t*, which condition must hold?
- C'(t*) > 0
- C'(t*) = 0
- C”(t*) > 0 always
- C(t*) = 0
Correct Answer: C'(t*) = 0
Q42. Differentiate f(x)=ln(sin x) using chain rule.
- cos x / sin x
- sin x / cos x
- ln(cos x)
- cos x · ln(sin x)
Correct Answer: cos x / sin x
Q43. The derivative of arccos(x) equals:
- -1/√(1-x2)
- 1/√(1-x2)
- -1/(1-x2)
- 1/(1-x2)
Correct Answer: -1/√(1-x2)
Q44. For f(x)= (x2+1)5, f'(x) is:
- 10x(x2+1)4
- 5(x2+1)4
- 2x(x2+1)5
- (x2+1)5
Correct Answer: 10x(x2+1)4
Q45. If f(x)=u(x)v(x)w(x), derivative requires:
- Pairwise product rule applied three times
- Sum of each function’s derivative times the product of the other two
- Only derivative of the largest function
- Quotient rule
Correct Answer: Sum of each function’s derivative times the product of the other two
Q46. The mean value theorem guarantees a point c where f'(c) equals:
- f(b) – f(a)
- f(b) + f(a)
- (f(b)-f(a))/(b-a)
- 0 always
Correct Answer: (f(b)-f(a))/(b-a)
Q47. The derivative of f(x)=sinh(x) is:
- cosh(x)
- sinh(x)
- ex
- tanh(x)
Correct Answer: cosh(x)
Q48. If concentration C(t)=At2-Bt+C, at t=1 the derivative C'(1) equals:
- 2A – B
- A – B + C
- 2A + B + C
- A + B
Correct Answer: 2A – B
Q49. For f(x)=arcsin(2x), f'(x) is:
- 2/√(1-4x2)
- 1/√(1-4x2)
- 2/√(1-x2)
- 1/√(1-x2)
Correct Answer: 2/√(1-4x2)
Q50. Which quantity is obtained by differentiating the area function A(t) under a release profile with respect to time?
- Cumulative release
- Instantaneous release rate (flux)
- Total drug released
- Average release over time
Correct Answer: Instantaneous release rate (flux)

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