Depression (including Suicidality) MCQ Quiz | General Psychiatry

1. According to DSM-5, which of the following is a mandatory core symptom for the diagnosis of Major Depressive Disorder (MDD)?

2. The monoamine hypothesis of depression primarily suggests a functional deficiency in which group of neurotransmitters?

3. A patient newly prescribed an SSRI like Fluoxetine should be counseled about which common initial side effect?

4. Which of the following is considered the strongest single predictor of a future suicide attempt?

5. Electroconvulsive Therapy (ECT) is considered a first-line treatment for which clinical presentation?

6. A key feature that distinguishes atypical depression from melancholic depression is:

7. A patient on Amitriptyline complains of dry mouth, blurred vision, and constipation. These side effects are due to the drug’s action on which receptors?

8. A patient on an SSRI is prescribed Tramadol and presents with confusion, hyperthermia, and myoclonus. This is most consistent with:

9. For a diagnosis of Persistent Depressive Disorder (Dysthymia) in an adult, depressed mood must be present for at least:

10. Aaron Beck’s cognitive theory of depression describes a “cognitive triad” of negative views about:

11. An actively suicidal patient with a clear plan and intent is in the ED. The most appropriate immediate management is:

12. A patient on an MAOI like Phenelzine must avoid tyramine-rich foods to prevent which complication?

13. The typical onset of postpartum depression (PPD), as distinct from “postpartum blues,” is usually within:

14. The most evidence-based first-line treatment for Seasonal Affective Disorder (SAD) is:

15. A patient presents with depressed mood, anergia, weight gain, and hypersomnia. A key medical condition to rule out is:

16. Venlafaxine is an antidepressant that primarily acts by inhibiting the reuptake of:

17. Which of the following is considered a protective factor against suicide?

18. Mirtazapine’s common side effect profile, which can be therapeutically useful, includes:

19. Which feature is more characteristic of Major Depressive Disorder than a normal grief reaction?

20. The hypothalamic-pituitary-adrenal (HPA) axis is often dysregulated in depression, leading to elevated levels of:

21. A widely used, two-question screening tool for depression in primary care is the:

22. Which antidepressant is a suitable choice for a patient with depression who also wants to quit smoking and is concerned about sexual side effects?

23. Regarding suicide epidemiology, which statement is generally true?

24. After a patient’s first episode of MDD achieves remission with an SSRI, the recommended duration for continuation therapy is typically:

25. When assessing a patient’s suicidal ideation, which question is most crucial to evaluate immediate risk?