Definition and classification of dosage forms MCQs With Answer

Introduction: Understanding the definition and classification of dosage forms is essential for B.Pharm students studying pharmaceutical formulation and drug delivery. This topic covers pharmaceutical dosage forms, including solid, liquid, semisolid, gaseous and parenteral preparations, plus routes of administration such as oral, topical, inhalation and parenteral. Key concepts include bioavailability, excipients, formulation principles, modified-release technologies, and regulatory classification. A clear grasp of dosage form types, examples and their advantages/disadvantages prepares students for formulation design, quality control and clinical application. Practical knowledge of dosage form properties and classification improves problem-solving in pharmaceutics and therapeutics. Now let’s test your knowledge with 30 MCQs on this topic.

Q1. What is the standard pharmacopeial definition of a ‘dosage form’?

  • A physical form in which a drug is produced and administered to achieve a therapeutic effect
  • The chemical structure of an active pharmaceutical ingredient
  • The biological effect produced by a drug in the body
  • A tablet coating material

Correct Answer: A physical form in which a drug is produced and administered to achieve a therapeutic effect

Q2. Which of the following is a primary classification of dosage forms by physical state?

  • Immediate and sustained release
  • Solid, liquid, semisolid and gaseous
  • Bitter and sweet
  • Tablets and capsules only

Correct Answer: Solid, liquid, semisolid and gaseous

Q3. Which classification is based on route of administration?

  • Oral, topical, parenteral, inhalation and rectal
  • Enteric-coated and film-coated
  • Immediate and delayed release
  • Dry and wet granulation

Correct Answer: Oral, topical, parenteral, inhalation and rectal

Q4. Which formulation is an example of a semisolid dosage form?

  • Tablet
  • Ointment
  • Solution
  • Powder

Correct Answer: Ointment

Q5. Which excipient primarily aids tablet disintegration?

  • Binder
  • Disintegrant
  • Lubricant
  • Coating polymer

Correct Answer: Disintegrant

Q6. Which dosage form is most appropriate for immediate systemic effect via bloodstream?

  • Intravenous injection
  • Topical cream
  • Enteric-coated tablet
  • Suppository

Correct Answer: Intravenous injection

Q7. What distinguishes modified-release from immediate-release dosage forms?

  • Modified-release alters drug release rate or site to improve therapy
  • Modified-release is always chewable
  • Immediate-release cannot be swallowed
  • Immediate-release is sterile

Correct Answer: Modified-release alters drug release rate or site to improve therapy

Q8. Which of the following is a type of modified-release system?

  • Enteric-coated tablet
  • Uncoated immediate tablet
  • Plain syrup
  • Simple ointment

Correct Answer: Enteric-coated tablet

Q9. Which dosage form classification focuses on rate and location of drug release?

  • Pharmaceutical process classification
  • Therapeutic classification
  • Release pattern classification
  • Color coding classification

Correct Answer: Release pattern classification

Q10. Which is an example of a liquid dosage form intended for systemic oral use?

  • Suspension
  • Ointment
  • Transdermal patch
  • Implant

Correct Answer: Suspension

Q11. Which statement best describes parenteral dosage forms?

  • Non-sterile liquids for oral use
  • Sterile preparations intended for injection or infusion bypassing the gastrointestinal tract
  • Topical creams applied to skin
  • Compressed tablets swallowed orally

Correct Answer: Sterile preparations intended for injection or infusion bypassing the gastrointestinal tract

Q12. Which base is commonly used for suppositories when heat-melting characteristic is required?

  • Polyethylene glycol (PEG) base
  • Gelatin capsule shell
  • Hydrophobic cocoa butter (theobroma oil)
  • Silicone fluid

Correct Answer: Hydrophobic cocoa butter (theobroma oil)

Q13. Which dosage form classification includes aerosols and inhalers?

  • Gaseous and aerosol dosage forms
  • Solid oral dosage forms
  • Semisolid topical forms
  • Parenteral implants only

Correct Answer: Gaseous and aerosol dosage forms

Q14. What is the main purpose of coating a tablet with enteric polymer?

  • Improve tablet color only
  • Prevent drug release in the stomach and allow release in the intestine
  • Increase mechanical hardness only
  • Promote immediate dissolution in gastric fluid

Correct Answer: Prevent drug release in the stomach and allow release in the intestine

Q15. Which classification relates to particle size and state: solution, suspension or colloid?

  • Physical state and dispersion classification
  • Therapeutic index classification
  • Pharmacodynamic classification
  • Regulatory scheduling classification

Correct Answer: Physical state and dispersion classification

Q16. Which excipient functions primarily as a binder in tablet granulation?

  • Lactose
  • Povidone (PVP)
  • Magnesium stearate
  • Sodium lauryl sulfate

Correct Answer: Povidone (PVP)

Q17. Which of the following is a sterile solid parenteral dosage form?

  • Lyophilized (freeze-dried) vial for reconstitution
  • Oral film
  • Topical gel
  • Effervescent tablet

Correct Answer: Lyophilized (freeze-dried) vial for reconstitution

Q18. Which dispersion type is characterized by droplets of oil in water?

  • Water-in-oil emulsion
  • Oil-in-water emulsion
  • Suspension of solids
  • Solution

Correct Answer: Oil-in-water emulsion

Q19. What characteristic defines a chewable tablet as a distinct dosage form?

  • It is designed to be chewed and swallowed without prior disintegration in the stomach
  • It requires injection
  • It is always enteric-coated
  • It must be refrigerated

Correct Answer: It is designed to be chewed and swallowed without prior disintegration in the stomach

Q20. Which dosage form classification addresses product stability and storage requirements?

  • Pharmaceutical stability classification
  • Therapeutic class only
  • Color classification
  • None of the above

Correct Answer: Pharmaceutical stability classification

Q21. Which is a common advantage of transdermal patches as a dosage form?

  • First-pass hepatic metabolism increases drug effect
  • Provides controlled systemic delivery and avoids first-pass metabolism
  • Requires frequent dosing every 30 minutes
  • Always non-occlusive and water soluble

Correct Answer: Provides controlled systemic delivery and avoids first-pass metabolism

Q22. Which oral dosage form provides the most rapid absorption under normal conditions?

  • Sustained-release tablet
  • Intravenous infusion
  • Orally disintegrating tablet (ODT)
  • Enteric-coated capsule

Correct Answer: Orally disintegrating tablet (ODT)

Q23. Which classification deals with therapeutic application of a dosage form (e.g., analgesics, antibiotics)?

  • Therapeutic or pharmacological classification
  • Physical state classification
  • Manufacturing process classification
  • Color coding classification

Correct Answer: Therapeutic or pharmacological classification

Q24. Which property is most critical for sterile parenteral solutions?

  • Viscosity only
  • Sterility and pyrogen-free status
  • Color uniformity
  • Flavor masking

Correct Answer: Sterility and pyrogen-free status

Q25. Which dosage form is particularly useful for drugs with poor oral bioavailability due to first-pass metabolism?

  • Topical cream only
  • Transdermal patch or parenteral route
  • Immediate-release oral tablet
  • Effervescent powder

Correct Answer: Transdermal patch or parenteral route

Q26. Which capsule type is used for delayed release consisting of multiple small pellets inside a single capsule?

  • Hard gelatin capsule containing multiparticulates (pellets)
  • Immediate-release film-coated tablet
  • Effervescent tablet
  • Transdermal matrix patch

Correct Answer: Hard gelatin capsule containing multiparticulates (pellets)

Q27. In classification by mechanism, which system uses osmotic pressure to control drug release?

  • Matrix diffusion system
  • Osmotic pump (osmotic-controlled release oral delivery system)
  • Immediate-release system
  • Buccal tablet

Correct Answer: Osmotic pump (osmotic-controlled release oral delivery system)

Q28. Which statement about suspensions is true?

  • Suspensions are homogeneous molecular solutions
  • Suspensions contain dispersed solid particles in a liquid vehicle and require proper wetting and stabilizers
  • Suspensions are identical to emulsions
  • Suspensions never require preservatives

Correct Answer: Suspensions contain dispersed solid particles in a liquid vehicle and require proper wetting and stabilizers

Q29. Which dosage form classification by release is intended to deliver drug at a constant rate over an extended period?

  • Immediate-release
  • Sustained or controlled-release
  • Enteric-release only
  • Topical only

Correct Answer: Sustained or controlled-release

Q30. Which factor is crucial when classifying dosage forms for pediatric use?

  • Taste masking, accurate dosing and age-appropriate administration (e.g., liquids, dispersible tablets)
  • Use of only transdermal patches
  • Mandatory parenteral administration for all drugs
  • Color preference only

Correct Answer: Taste masking, accurate dosing and age-appropriate administration (e.g., liquids, dispersible tablets)

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