COPD MCQ Quiz | Respiratory System

1. Which post-bronchodilator spirometric value is the diagnostic hallmark of COPD?

2. The primary pathological change in emphysema involves:

3. Which genetic deficiency is a well-established risk factor for early-onset panacinar emphysema?

4. A patient with severe dyspnea, a barrel-shaped chest, weight loss, and minimal cyanosis is classically described as a:

5. According to the GOLD guidelines, what FEV1 percentage of predicted value corresponds to GOLD Stage 3 (Severe) COPD?

6. For a patient with symptomatic COPD (GOLD Group B), what is the recommended initial pharmacological treatment?

7. In which group of COPD patients are inhaled corticosteroids (ICS) most strongly indicated as part of a combination therapy?

8. What is the most common trigger for an acute exacerbation of COPD (AECOPD)?

9. The cornerstone of managing a hospitalized patient with AECOPD includes which three interventions?

10. What is the target oxygen saturation (SpO2) range for a patient with AECOPD at risk of hypercapnic respiratory failure?

11. Cor pulmonale in a COPD patient is best defined as:

12. A chest X-ray of a patient with severe emphysema is most likely to show:

13. Which non-pharmacological intervention has the highest level of evidence for improving dyspnea, exercise tolerance, and quality of life in stable COPD patients?

14. What is the single most effective and cost-effective intervention to slow the progression of COPD in patients who smoke?

15. In which type of COPD is the diffusing capacity of the lung for carbon monoxide (DLCO) typically most significantly reduced?

16. The Reid Index, used to quantify the severity of chronic bronchitis, measures the ratio of:

17. Which two vaccinations are strongly recommended for all patients with COPD to prevent exacerbations?

18. The BODE index is a multidimensional grading system that predicts mortality in COPD. What does the ‘E’ in BODE stand for?

19. Which of the following is a Long-Acting Muscarinic Antagonist (LAMA) commonly used in COPD management?

20. A patient with known severe COPD presents with acute confusion. Arterial blood gas analysis shows pH 7.25, PaCO2 80 mmHg, and PaO2 50 mmHg. This is indicative of:

21. Besides viruses, which are the three most common bacterial pathogens implicated in AECOPD?

22. Lung Volume Reduction Surgery (LVRS) is a potential treatment for which specific subgroup of COPD patients?

23. Airflow limitation in COPD is characteristically:

24. The ‘blue bloater’ clinical phenotype is more classically associated with which component of COPD?

25. What does FEV1 measure in spirometry?