Benign Breast Disorders (ANDI/Fibroadenoma/Cysts) MCQ Quiz | Breast

1. The term ANDI (Aberrations of Normal Development and Involution) primarily emphasizes that most benign breast conditions are:

2. A 22-year-old female presents with a highly mobile, firm, non-tender, 2 cm lump in her left breast. What is the most likely diagnosis?

3. A 45-year-old woman presents with a suddenly appearing, tender, smooth lump in her breast. Ultrasound confirms a simple cyst. What is the most appropriate next step in management?

4. The characteristic “popcorn calcification” on a mammogram is most suggestive of which benign condition?

5. In the context of ANDI, cyclical mastalgia and breast nodularity are most common in which age group?

6. What is the classic color of the fluid aspirated from a simple breast cyst?

7. A fibroadenoma is a biphasic tumor, meaning it is composed of which two types of tissue?

8. Which of the following is the primary indication for surgical excision of a fibroadenoma in a 25-year-old woman?

9. After aspirating a simple breast cyst, the lump completely disappears, and the fluid is non-bloody. What is the recommended follow-up?

10. A 28-year-old female complains of bilateral, diffuse breast pain that worsens before her menstrual periods. Examination reveals ‘lumpy’ breasts but no dominant mass. This clinical picture is best described as:

11. The “triple assessment” for a breast lump consists of:

12. A complex breast cyst on ultrasound is characterized by which of the following features, warranting further investigation?

13. Which of the following is NOT a first-line treatment for cyclical mastalgia?

14. A 16-year-old girl presents with a rapidly growing, 6 cm breast mass. Histology confirms a benign biphasic tumor with increased stromal cellularity. What is the most specific diagnosis?

15. The risk of malignancy developing within a simple fibroadenoma is:

16. Which hormone is most strongly implicated in the cyclical changes seen in ANDI?

17. Fibroadenomas are often hormonally sensitive. They tend to increase in size during:

18. A cyst is aspirated and the fluid is found to be blood-stained. What is the mandatory next step?

19. The term ‘breast mouse’ refers to the clinical finding of a:

20. What is the most appropriate imaging modality for a suspected breast lump in a woman under 35 years of age?

21. In the histological classification of fibroadenomas, the ‘intracanalicular’ pattern describes:

22. A 50-year-old perimenopausal woman is diagnosed with multiple, small, asymptomatic simple cysts on a routine mammogram. The appropriate management is:

23. Sclerosing adenosis is a component of ANDI that can mimic malignancy on mammogram due to:

24. What is the most definitive method to distinguish a benign fibroadenoma from a phyllodes tumor?

25. A breast cyst is aspirated, but a residual lump remains. The next most appropriate step is: