Anal Cancer MCQ Quiz | Anorectal

Welcome to the Anal Cancer MCQ quiz, designed for MBBS students to test and enhance their knowledge in the field of Anorectal surgery. This quiz covers key areas including epidemiology, risk factors, pathophysiology, clinical presentation, diagnosis, staging, and management of anal cancer. It comprises 25 carefully curated multiple-choice questions that reflect the core curriculum. This assessment is an excellent tool for self-evaluation and revision before your professional examinations. After completing the quiz, you can submit your answers to see your score and review the correct responses. You will also have the option to download a PDF document containing all the questions and their correct answers for your future reference and study. Good luck!

1. What is the most common histological type of anal canal cancer?

2. The primary etiological agent strongly associated with the development of most anal squamous cell carcinomas is:

3. What is the most common presenting symptom of anal cancer?

4. The standard of care for most localized, non-metastatic anal canal squamous cell carcinoma is:

5. Lymphatic drainage from the anal canal ABOVE the dentate line primarily flows to which group of nodes?

6. The original Nigro protocol for chemoradiation in anal cancer consists of radiotherapy combined with which two chemotherapy agents?

7. In the TNM staging of anal cancer, what does a T1 tumor signify?

8. Bowen’s disease of the perianal skin is a form of:

9. Abdominoperineal resection (APR) is primarily reserved for which scenario in anal cancer management?

10. Which imaging modality is most sensitive for assessing local tumor invasion and lymph node involvement in anal cancer staging?

11. Cancers of the anal margin are often treated similarly to skin cancers. Which treatment is most appropriate for a small, well-differentiated T1 anal margin SCC?

12. The gold standard for definitive diagnosis of anal cancer is:

13. Which of the following conditions is NOT a significant risk factor for anal cancer?

14. Lymphatic drainage from the anal canal BELOW the dentate line primarily targets which nodes?

15. The most common site for distant metastasis from anal cancer is the:

16. Which HPV subtypes are most frequently associated with anal cancer?

17. Basaloid carcinoma, also known as cloacogenic carcinoma, arises from which anatomical region?

18. A patient is found to have inguinal lymph node metastasis from an anal canal SCC. How should these nodes be managed?

19. Which of the following is a common acute toxicity associated with chemoradiation for anal cancer?

20. What is the role of PET/CT scan in the management of anal cancer?

21. The anal margin is anatomically defined as the area extending from the anal verge to a radius of:

22. Adenocarcinoma of the anal canal is rare and is typically thought to arise from:

23. Post-treatment surveillance for anal cancer typically includes regular digital rectal exams, anoscopy, and which other important component?

24. What is the primary purpose of the HPV vaccine in relation to anal cancer?

25. Which two factors are the most important prognostic indicators for survival in patients with anal cancer?