MCQ Quiz: Liquid Dosage Forms

Liquid dosage forms are a cornerstone of pharmaceutical science, offering advantages like easier administration, flexible dosing, and rapid absorption. For B.Pharm students, mastering the formulation and principles of both monophasic and biphasic liquids is essential. This quiz covers key topics, including syrups, elixirs, suspensions, and emulsions, focusing on their preparation, stability, and classification, which are vital for effective pharmaceutical practice.


  1. Which of the following is a biphasic liquid dosage form?
    • Syrup
    • Elixir
    • Emulsion
    • Lotion
    Answer: Emulsion
  2. Clear, sweetened, hydroalcoholic solutions for oral use are known as:
    • Syrups
    • Suspensions
    • Elixirs
    • Gargles
    Answer: Elixirs
  3. In a suspension, the formation of a hard, non-resuspendable sediment is called:
    • Flocculation
    • Creaming
    • Caking
    • Coalescence
    Answer: Caking
  4. The HLB (Hydrophile-Lipophile Balance) system is used to select an appropriate:
    • Sweetening agent
    • Preservative
    • Emulsifying agent
    • Suspending agent
    Answer: Emulsifying agent
  5. Which of the following is a primary advantage of liquid dosage forms?
    • They are always more stable than solid forms.
    • They offer ease of administration for pediatric and geriatric patients.
    • They have no taste or odor issues.
    • They have a longer shelf life than powders.
    Answer: They offer ease of administration for pediatric and geriatric patients.
  6. A suspension in which particles form loosely-packed aggregates is known as a(n):
    • Deflocculated suspension
    • Flocculated suspension
    • Emulsion
    • Solution
    Answer: Flocculated suspension
  7. Syrups are concentrated aqueous solutions of:
    • Alcohol
    • Salt
    • Sugar
    • Oil
    Answer: Sugar
  8. The dilution test is used to identify the type of a(n):
    • Suspension
    • Elixir
    • Syrup
    • Emulsion
    Answer: Emulsion
  9. Liniments are intended to be applied to the skin with:
    • No friction
    • Friction and rubbing
    • A sterile bandage
    • Water
    Answer: Friction and rubbing
  10. The irreversible merging of smaller droplets into larger ones in an emulsion is called:
    • Creaming
    • Sedimentation
    • Coalescence
    • Flocculation
    Answer: Coalescence
  11. Which of the following is an example of a monophasic liquid dosage form?
    • Suspension
    • Emulsion
    • Mouthwash
    • Magma
    Answer: Mouthwash
  12. The main difference between a lotion and a liniment is the:
    • Route of administration
    • Method of application
    • Viscosity
    • Active ingredient
    Answer: Method of application
  13. In a deflocculated suspension, the particles settle:
    • Rapidly to form a loose sediment
    • Slowly to form a dense, hard cake
    • Not at all
    • As flocs
    Answer: Slowly to form a dense, hard cake
  14. Which excipient is used in liquid formulations to prevent the growth of microorganisms?
    • Sweetener
    • Flavoring agent
    • Coloring agent
    • Preservative
    Answer: Preservative
  15. An o/w emulsion will be miscible with:
    • Oil
    • Water
    • Both oil and water
    • Neither oil nor water
    Answer: Water
  16. Gargles are aqueous solutions used for treating infections of the:
    • Stomach
    • Ear canal
    • Throat
    • Nasal passages
    Answer: Throat
  17. The upward movement of the dispersed phase in an emulsion is termed:
    • Sedimentation
    • Cracking
    • Creaming
    • Phase inversion
    Answer: Creaming
  18. The main vehicle in an elixir is a blend of:
    • Water and sugar
    • Water and oil
    • Water and alcohol
    • Water and glycerin
    Answer: Water and alcohol
  19. A substance that increases the viscosity of the dispersion medium in a suspension is a(n):
    • Emulsifying agent
    • Wetting agent
    • Suspending agent
    • Flocculating agent
    Answer: Suspending agent
  20. Throat paints are typically more ______ than gargles.
    • Dilute
    • Viscous
    • Volatile
    • Palatable
    Answer: Viscous
  21. Which of the following is NOT a method for solubility enhancement?
    • Use of co-solvents
    • Complexation
    • Particle size reduction
    • Use of an anti-adherent
    Answer: Use of an anti-adherent
  22. The complete and irreversible separation of the two phases in an emulsion is called:
    • Creaming
    • Breaking (or cracking)
    • Sedimentation
    • Phase inversion
    Answer: Breaking (or cracking)
  23. Enemas are liquid preparations administered:
    • Orally
    • Topically
    • Rectally
    • Ocularly
    Answer: Rectally
  24. Stoke’s Law describes the:
    • Rate of dissolution
    • Rate of sedimentation in a suspension
    • Stability of an emulsion
    • Surface tension of a liquid
    Answer: Rate of sedimentation in a suspension
  25. The primary purpose of a vehicle in a liquid dosage form is to:
    • Act as the therapeutic agent
    • Provide a pleasant taste
    • Act as a carrier for the active ingredients
    • Prevent microbial growth
    Answer: Act as a carrier for the active ingredients
  26. In an o/w emulsion, the continuous phase is:
    • Oil
    • Water
    • Solid particles
    • Air
    Answer: Water
  27. A major disadvantage of liquid dosage forms is their:
    • Slower onset of action compared to solids
    • Bulkiness and potential for lower stability
    • Inflexibility in dosing
    • Difficulty in swallowing
    Answer: Bulkiness and potential for lower stability
  28. Which of the following is used to treat conditions of the ear?
    • Nasal drops
    • Gargles
    • Enemas
    • Ear drops
    Answer: Ear drops
  29. The dye test for emulsion identification involves adding a(n) ______ dye to the sample.
    • water-soluble
    • oil-soluble
    • insoluble
    • fluorescent
    Answer: oil-soluble
  30. What is the primary difference between a suspension and a solution?
    • Suspensions are clear, while solutions are cloudy.
    • In a solution, the drug is dissolved; in a suspension, it is dispersed as solid particles.
    • Suspensions are always for oral use.
    • Solutions contain an emulsifying agent.
    Answer: In a solution, the drug is dissolved; in a suspension, it is dispersed as solid particles.
  31. Which of the following would NOT be considered an excipient in a liquid dosage form?
    • Vehicle
    • Active Pharmaceutical Ingredient (API)
    • Preservative
    • Coloring agent
    Answer: Active Pharmaceutical Ingredient (API)
  32. A “shake well before use” label is mandatory for which dosage form?
    • Elixir
    • Syrup
    • Suspension
    • Solution
    Answer: Suspension
  33. Phase inversion of an emulsion is the process where:
    • The emulsion breaks
    • The droplets cream
    • An o/w emulsion changes to a w/o emulsion
    • The droplets coalesce
    Answer: An o/w emulsion changes to a w/o emulsion
  34. Mouthwashes are primarily used to:
    • Treat throat infections
    • Cleanse and deodorize the oral cavity
    • Be swallowed for systemic effect
    • Provide medication to the lungs
    Answer: Cleanse and deodorize the oral cavity
  35. The rate of sedimentation in a suspension is ______ to the viscosity of the dispersion medium.
    • directly proportional
    • inversely proportional
    • not related
    • equal
    Answer: inversely proportional
  36. An emulsifying agent with a high HLB value (e.g., 8-18) is suitable for forming a(n):
    • w/o emulsion
    • o/w emulsion
    • suspension
    • solution
    Answer: o/w emulsion
  37. Which of the following is NOT a desirable property of a pharmaceutical suspension?
    • The particles should settle slowly.
    • The sediment should be easily re-dispersible.
    • The sediment should form a hard cake.
    • It should have an elegant appearance.
    Answer: The sediment should form a hard cake.
  38. The term “monophasic” means the system consists of:
    • One phase
    • Two phases
    • Three phases
    • Solid and liquid phases
    Answer: One phase
  39. Which liquid dosage form is applied to the skin without friction and usually for a protective or emollient effect?
    • Liniment
    • Lotion
    • Throat paint
    • Collodion
    Answer: Lotion
  40. The continental or “dry gum” method is a technique used to prepare:
    • Suspensions
    • Syrups
    • Elixirs
    • Emulsions
    Answer: Emulsions
  41. A wetting agent is often added to suspensions to:
    • Increase viscosity
    • Improve the dispersion of hydrophobic solid particles in the aqueous vehicle
    • Prevent microbial growth
    • Sweeten the preparation
    Answer: Improve the dispersion of hydrophobic solid particles in the aqueous vehicle
  42. A liquid dosage form containing one or more active ingredients dissolved in a suitable solvent is a(n):
    • Suspension
    • Emulsion
    • Solution
    • Magma
    Answer: Solution
  43. Compared to syrups, elixirs are generally:
    • More viscous
    • Sweeter
    • Less stable
    • Less effective at masking taste
    Answer: Less stable
  44. The “caking” of a suspension is a sign of:
    • Good stability
    • Flocculation
    • Irreversible instability
    • A properly formulated product
    Answer: Irreversible instability
  45. Which of the following is NOT a type of monophasic liquid?
    • Drops
    • Liniment
    • Gargle
    • Gel
    Answer: Gel
  46. The dispersed phase in an o/w emulsion consists of:
    • Water globules
    • Oil globules
    • Solid particles
    • Gas bubbles
    Answer: Oil globules

4t7. A key stability concern for elixirs is: * Sedimentation * Evaporation of the alcohol * Caking * Creaming

**Answer:** Evaporation of the alcohol
  1. The flocculated state in a suspension is generally considered to be:
    • An undesirable sign of instability
    • A desirable state to prevent caking
    • The final stage before breaking
    • A sign of microbial growth
    Answer: A desirable state to prevent caking
  2. Which of the following can be used for both internal and external purposes?
    • Liniments
    • Enemas
    • Lotions
    • Solutions
    Answer: Solutions
  3. The classification of a liquid dosage form as biphasic means it contains:
    • Two active ingredients
    • Two distinct immiscible phases
    • Two different solvents
    • Two preservatives
    Answer: Two distinct immiscible phases

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