Pharmaceutical analysis is the cornerstone of quality control in the pharmaceutical industry, ensuring that all drug products are pure, safe, and effective. For B.Pharm students, mastering the principles of classical and instrumental analysis, from titrations to electrochemical methods, is non-negotiable. This quiz covers fundamental concepts of analytical chemistry as they apply to pharmaceuticals, providing a robust test of your knowledge in this critical subject.
- A substance of high purity that is used to standardize a solution is known as a:
- Titrant
- Primary standard
- Secondary standard
- Analyte
- The closeness of a measured value to the true or accepted value is called:
- Precision
- Accuracy
- Range
- Deviation
- Which of the following is an official book of standards for drugs and pharmaceuticals?
- Journal
- Textbook
- Dictionary
- Pharmacopoeia
- Limit tests are quantitative or semi-quantitative tests designed to:
- Identify and quantify the active ingredient
- Determine the physical properties of a substance
- Identify and control small quantities of impurities
- Measure the concentration of a solution
- In acid-base titrations, the point at which the reaction between the acid and base is complete is the:
- End point
- Equivalence point
- Neutralization point
- Indicator point
- Titrations carried out in solvents other than water are known as:
- Aqueous titrations
- Redox titrations
- Non-aqueous titrations
- Complexometric titrations
- Mohr’s method for precipitation titration uses which of the following as an indicator?
- Ferric alum
- Eosin
- Potassium chromate
- Methyl orange
- EDTA (ethylenediaminetetraacetic acid) is a common titrant used in which type of titration?
- Acid-base
- Redox
- Precipitation
- Complexometric
- The principle of gravimetric analysis is based on the measurement of:
- Volume
- Mass
- Potential
- Conductance
- Redox titrations involve the transfer of:
- Protons
- Electrons
- Neutrons
- Ions
- The calomel electrode is a common type of:
- Indicator electrode
- Reference electrode
- Working electrode
- Glass electrode
- Which electrochemical method measures the current flowing through a solution as a function of applied voltage?
- Potentiometry
- Conductometry
- Polarography
- Amperometry
- Which type of error arises from a flaw in the experimental design or equipment?
- Random error
- Personal error
- Systematic error
- Gross error
- In the limit test for iron, the purple color is due to the formation of a complex between ferrous iron and:
- Thioglycollic acid
- Citric acid
- Hydrochloric acid
- Ammonia
- Which indicator is commonly used in the titration of a strong acid with a strong base?
- Phenolphthalein
- Thymol blue
- Eriochrome Black T
- Starch
- Volhard’s method is an example of a(n):
- Direct titration
- Back titration
- Non-aqueous titration
- Acid-base titration
- Agents that prevent the interference of certain ions in complexometric titrations are known as:
- Indicators
- Buffers
- Masking agents
- Demasking agents
- In iodometry, the liberated iodine is titrated against a standard solution of:
- Potassium permanganate
- Ceric ammonium sulphate
- Sodium thiosulphate
- Potassium dichromate
- Conductivity of a solution depends on:
- The size of the ions
- The charge on the ions
- The mobility of the ions
- All of the above
- The dropping mercury electrode (DME) is a key component in which analytical technique?
- Potentiometry
- Conductometry
- Polarography
- Gravimetry
- The closeness of a set of measurements to each other is known as:
- Accuracy
- Precision
- Mean
- Bias
- Which of the following is commonly used as a solvent in non-aqueous acidimetry?
- Water
- Dimethylformamide
- Ethanol
- Acetone
- Fajans method of precipitation titration uses which type of indicator?
- Metal-ion indicator
- Redox indicator
- Adsorption indicator
- Acid-base indicator
- The impurity of the precipitate where a soluble impurity is incorporated into the crystal lattice is called:
- Post-precipitation
- Co-precipitation
- Occlusion
- Surface adsorption
- Cerimetry is a type of redox titration that uses which titrant?
- Ceric sulphate
- Potassium permanganate
- Iodine
- Sodium thiosulphate
- Potentiometry involves the measurement of:
- Resistance
- Current
- Potential difference (voltage)
- Conductance
- The Ilkovic equation is associated with which analytical method?
- Potentiometry
- Conductometry
- Polarography
- Spectrophotometry
- Which of the following is an example of a primary standard?
- Sodium hydroxide
- Hydrochloric acid
- Potassium hydrogen phthalate
- Potassium permanganate
- The Gutzeit test is used for the limit test of:
- Lead
- Iron
- Chloride
- Arsenic
- A neutralization curve is a plot of pH against:
- Temperature
- Concentration of indicator
- Volume of titrant added
- Time
- Eriochrome Black T is a common indicator for:
- Acid-base titrations
- Redox titrations
- Complexometric titrations
- Precipitation titrations
- The direct titration of iodine against a reducing agent is known as:
- Iodometry
- Iodimetry
- Bromatometry
- Dichrometry
- A conductivity cell is composed of two:
- Platinum electrodes
- Glass electrodes
- Calomel electrodes
- Silver electrodes
- Which reference electrode consists of mercury, mercurous chloride, and a saturated KCl solution?
- Standard Hydrogen Electrode (SHE)
- Silver/Silver Chloride Electrode
- Calomel Electrode
- Glass Electrode
- The number of significant figures in the value 0.05010 is:
- 3
- 4
- 5
- 6
- The limit test for chlorides is based on the reaction of soluble chlorides with silver nitrate in the presence of:
- Dilute nitric acid
- Dilute sulphuric acid
- Dilute hydrochloric acid
- Dilute acetic acid
- In precipitation titrations by Fajans method, the end point is indicated by a:
- Change in color of the solution
- Change in color of the precipitate
- Formation of a precipitate
- Disappearance of a precipitate
- The process of heating a gravimetric precipitate to a constant weight is called:
- Digestion
- Ignition
- Peptization
- Filtration
- In redox titrations using potassium permanganate, the indicator used is:
- Starch
- Ferric alum
- Potassium permanganate itself
- Methyl orange
- The glass electrode is a type of:
- Reference electrode
- Ion-selective electrode
- Metal electrode
- Redox electrode
- The diffusion current in polarography is directly proportional to the:
- Temperature of the solution
- Concentration of the electroactive species
- Viscosity of the solution
- Size of the mercury drop
- A solution of known concentration used in a titration is a:
- Standard solution
- Saturated solution
- Buffer solution
- Test solution
- Which solvent is used as a titrant for the estimation of weak bases in non-aqueous titrations?
- Acetic acid
- Sodium hydroxide
- Perchloric acid
- Acetone
- What is the primary requirement for a metal-ion indicator in complexometric titrations?
- It must be a strong oxidizing agent.
- It must bind less strongly to the metal ion than the titrant.
- It must be insoluble in the solvent.
- It must be a primary standard.
- The technique that measures the change in electrical conductivity of a solution during titration is:
- Potentiometric titration
- Conductometric titration
- Amperometric titration
- Polarographic titration
- The Standard Hydrogen Electrode (SHE) is assigned a potential of:
- 1.00 V
- 0.50 V
- 0.00 V
- -1.00 V
- Titration of a colored solution is best carried out using which method?
- Visual indicator method
- Potentiometry
- Acid-base titration
- Direct titration
- In the standardization of sodium thiosulphate, the primary standard used is:
- Potassium dichromate
- Oxalic acid
- Sodium carbonate
- Ferrous ammonium sulphate
- Diazotization titration is used for the estimation of:
- Primary aromatic amines
- Alcohols
- Aldehydes
- Carboxylic acids
- The opalescence in the limit test for chloride is compared against a:
- Test solution
- Blank solution
- Standard solution
- Saturated solution
I am a Registered Pharmacist under the Pharmacy Act, 1948, and the founder of PharmacyFreak.com. I hold a Bachelor of Pharmacy degree from Rungta College of Pharmaceutical Science and Research. With a strong academic foundation and practical knowledge, I am committed to providing accurate, easy-to-understand content to support pharmacy students and professionals. My aim is to make complex pharmaceutical concepts accessible and useful for real-world application.
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