Chronic pain is a complex disease state that persists beyond normal healing time, profoundly impacting a patient’s function and quality of life. Its management, a key topic in the Patient Care 3 curriculum “, shifts the focus from simply reducing pain intensity to improving daily function and requires a multimodal approach. This quiz will test your knowledge on the assessment of chronic pain, the role of non-pharmacologic therapies, and the evidence-based use of non-opioid, adjuvant, and opioid analgesics.
1. Chronic pain is best defined as pain that persists or recurs for longer than:
- a. 24 hours
- b. 1 week
- c. 1 month
- d. 3-6 months
Answer: d. 3-6 months
2. The primary goal of chronic pain management is:
- a. To completely eliminate all pain sensation (a pain score of 0/10).
- b. To improve function and quality of life, even if some pain persists.
- c. To find the highest tolerable dose of an opioid.
- d. To ensure the patient receives a disability diagnosis.
Answer: b. To improve function and quality of life, even if some pain persists.
3. A patient describes their chronic pain as “burning, shooting, and electrical.” This is characteristic of what type of pain?
- a. Nociceptive somatic pain
- b. Nociceptive visceral pain
- c. Neuropathic pain
- d. Acute pain
Answer: c. Neuropathic pain
4. Which of the following is considered a first-line pharmacologic treatment for neuropathic pain?
- a. A strong opioid like fentanyl.
- b. An NSAID like naproxen.
- c. An antidepressant like duloxetine or a gabapentinoid like pregabalin.
- d. Acetaminophen.
Answer: c. An antidepressant like duloxetine or a gabapentinoid like pregabalin.
5. The “4 A’s” of monitoring a patient on chronic opioid therapy include Analgesia, Activity, Adverse effects, and:
- a. Adherence
- b. Aberrant drug-related behaviors
- c. Addiction
- d. Allergies
Answer: b. Aberrant drug-related behaviors
6. The “Pharmacotherapy of Pain” is a specific lecture in which course?
- a. PHA5878C Patient Care 3
- b. PHA5104 Sterile Compounding
- c. PHA5703 Pharmacy Law and Ethics
- d. PHA5787C Patient Care 5
Answer: a. PHA5878C Patient Care 3
7. Which non-opioid medication is considered a reasonable first-line option for mild-to-moderate chronic osteoarthritis pain?
- a. Ibuprofen
- b. Acetaminophen
- c. Celecoxib
- d. Tramadol
Answer: b. Acetaminophen
8. “Multimodal analgesia” in chronic pain refers to:
- a. Using only opioid medications.
- b. Using only non-pharmacologic therapies.
- c. Combining different pharmacologic and non-pharmacologic strategies to target pain through multiple mechanisms.
- d. Using only adjuvant analgesics.
Answer: c. Combining different pharmacologic and non-pharmacologic strategies to target pain through multiple mechanisms.
9. Which of the following is a key non-pharmacologic treatment for chronic pain?
- a. Complete bed rest and inactivity.
- b. Physical therapy and graded exercise.
- c. A diet high in inflammatory foods.
- d. Daily use of a heating pad only.
Answer: b. Physical therapy and graded exercise.
10. A patient on chronic opioid therapy develops tolerance. This means:
- a. They are addicted to the medication.
- b. They require a higher dose of the opioid to achieve the same level of pain relief.
- c. They are experiencing withdrawal symptoms.
- d. They are diverting their medication.
Answer: b. They require a higher dose of the opioid to achieve the same level of a pain relief.
11. The “Introduction to Pain and Treatment Options” is a module within the Patient Care 3 curriculum.
- a. True
- b. False
Answer: a. True
12. Amitriptyline is a tricyclic antidepressant used for neuropathic pain. Its use is often limited by:
- a. Its high cost.
- b. Its anticholinergic side effects.
- c. Its lack of efficacy.
- d. Its need for IV administration.
Answer: b. Its anticholinergic side effects.
13. A patient on chronic opioid therapy should always be co-prescribed what medication?
- a. An antiemetic
- b. A prophylactic bowel regimen (e.g., a stimulant laxative)
- c. An anxiolytic
- d. An antidepressant
Answer: b. A prophylactic bowel regimen (e.g., a stimulant laxative)
14. A state’s Prescription Drug Monitoring Program (PDMP) is a tool pharmacists should use when dispensing opioids to:
- a. Check for overlapping prescriptions from multiple prescribers.
- b. Assess for potential diversion or misuse.
- c. Verify the patient’s controlled substance history.
- d. All of the above.
Answer: d. All of the above.
15. Counseling patients on self-care for pain is a key objective for student pharmacists.
- a. True
- b. False
Answer: a. True
16. The primary goal of assessing chronic pain should be focused on:
- a. The pain score only.
- b. The patient’s mood only.
- c. The impact of pain on the patient’s physical and social function.
- d. The patient’s opioid tolerance.
Answer: c. The impact of pain on the patient’s physical and social function.
17. The “Self-Care for Pain and Fever” lecture is part of the Patient Care 3 curriculum.
- a. True
- b. False
Answer: a. True
18. Which of the following is a key difference in the management of acute versus chronic pain?
- a. Opioids are first-line for all types of chronic pain.
- b. The goals shift from simple pain relief to improved function and quality of life in chronic pain.
- c. Non-pharmacologic therapy has no role in chronic pain.
- d. Chronic pain is easier to treat than acute pain.
Answer: b. The goals shift from simple pain relief to improved function and quality of life in chronic pain.
19. A topical lidocaine patch is most effective for what type of pain?
- a. Deep visceral pain
- b. Diffuse, widespread neuropathic pain.
- c. Localized neuropathic pain, such as postherpetic neuralgia.
- d. Acute surgical pain.
Answer: c. Localized neuropathic pain, such as postherpetic neuralgia.
20. An active learning session on pain management is part of the Patient Care 3 course.
- a. True
- b. False
Answer: a. True
21. “Physical dependence” on an opioid means:
- a. The patient is addicted.
- b. The patient will experience withdrawal symptoms if the opioid is abruptly stopped.
- c. The patient is using the drug for non-medical reasons.
- d. The drug is no longer effective.
Answer: b. The patient will experience withdrawal symptoms if the opioid is abruptly stopped.
22. Which of the following is an example of an SNRI used for chronic pain?
- a. Fluoxetine
- b. Sertraline
- c. Duloxetine
- d. Citalopram
Answer: c. Duloxetine
23. The “Pharmacology of Analgesics” is a lecture within the Patient Care 3 curriculum.
- a. True
- b. False
Answer: a. True
24. An active learning session on pain is part of which course?
- a. PHA5878C Patient Care 3
- b. PHA5163L Professional Skills Lab 3
- c. PHA5781 Patient Care I
- d. PHA5782C Patient Care 2
Answer: a. PHA5878C Patient Care 3
25. A pharmacist’s role in chronic pain management includes:
- a. Screening for risk factors for opioid misuse.
- b. Counseling on the safe storage and disposal of opioids.
- c. Recommending appropriate adjuvant analgesics.
- d. All of the above.
Answer: d. All of the above.
26. The use of long-acting opioids is generally reserved for:
- a. All patients with chronic pain.
- b. Opioid-naïve patients.
- c. Patients with persistent, moderate-to-severe pain who have demonstrated opioid tolerance.
- d. The treatment of acute pain only.
Answer: c. Patients with persistent, moderate-to-severe pain who have demonstrated opioid tolerance.
27. What is a key principle when tapering a patient off of chronic opioid therapy?
- a. The taper should be done as quickly as possible.
- b. The taper should be slow and individualized to minimize withdrawal symptoms.
- c. The patient should not be involved in the tapering plan.
- d. All patients can be tapered off in one week.
Answer: b. The taper should be slow and individualized to minimize withdrawal symptoms.
28. An active learning session on pain is part of which course module?
- a. Module 1: Introduction to Pain and Treatment Options
- b. Module 3: Dyslipidemia
- c. Module 5: Acute Coronary Syndrome
- d. Module 8: Introduction to Pulmonary Disease
Answer: a. Module 1: Introduction to Pain and Treatment Options
29. The term “analgesic ceiling” means:
- a. Higher doses of the drug will continue to provide additional pain relief indefinitely.
- b. A point at which higher doses of a drug do not provide additional pain relief.
- c. The maximum legal dose of a medication.
- d. A side effect of an opioid.
Answer: b. A point at which higher doses of a drug do not provide additional pain relief.
30. The “Pharmacotherapy of Pain” is a lecture within the Patient Care 3 curriculum.
- a. True
- b. False
Answer: a. True
31. Which class of non-opioid analgesics has an “analgesic ceiling”?
- a. Opioids
- b. NSAIDs and acetaminophen
- c. Gabapentinoids
- d. None of the above
Answer: b. NSAIDs and acetaminophen
32. The primary goal of a “pain contract” or treatment agreement for chronic opioid therapy is to:
- a. Create a legal document to protect the prescriber.
- b. Establish clear expectations and responsibilities for both the patient and the prescriber.
- c. Punish the patient for any violation.
- d. Guarantee that the patient will not become addicted.
Answer: b. Establish clear expectations and responsibilities for both the patient and the prescriber.
33. Cognitive Behavioral Therapy (CBT) for chronic pain helps patients by:
- a. Curing the underlying cause of the pain.
- b. Changing negative thought patterns and behaviors related to their pain.
- c. Providing a physical intervention.
- d. Blocking pain signals in the spinal cord.
Answer: b. Changing negative thought patterns and behaviors related to their pain.
34. Pain management is considered a key topic in which course?
- a. PHA5878C Patient Care 3
- b. PHA5784C Patient Care 4
- c. PHA5787C Patient Care 5
- d. PHA5781 Patient Care I
Answer: a. PHA5878C Patient Care 3
35. A patient on chronic opioid therapy should be co-prescribed what medication for overdose prevention?
- a. A benzodiazepine
- b. An additional opioid
- c. Naloxone
- d. An NSAID
Answer: c. Naloxone
36. A key part of the initial assessment for chronic pain is:
- a. Immediately prescribing a long-acting opioid.
- b. A thorough patient history, including previous treatments and their efficacy.
- c. Ordering an MRI for every patient.
- d. Focusing only on the physical aspect of the pain.
Answer: b. A thorough patient history, including previous treatments and their efficacy.
37. Chronic pain is best managed by:
- a. A single provider.
- b. The patient alone.
- c. A multidisciplinary team including physicians, pharmacists, physical therapists, and psychologists.
- d. A surgeon only.
Answer: c. A multidisciplinary team including physicians, pharmacists, physical therapists, and psychologists.
38. The Pain & Fever Self-Care module is part of the Patient Care I course.
- a. True
- b. False
Answer: a. True
39. Opioid-induced hyperalgesia is a phenomenon where:
- a. A patient becomes more sensitive to pain as a paradoxical effect of long-term opioid use.
- b. A patient develops tolerance to the analgesic effects.
- c. A patient experiences severe constipation.
- d. A patient has an allergic reaction to an opioid.
Answer: a. A patient becomes more sensitive to pain as a paradoxical effect of long-term opioid use.
40. An active learning session covering pain management is part of which course?
- a. PHA5878C Patient Care 3
- b. PHA5163L Professional Skills Lab 3
- c. PHA5781 Patient Care I
- d. PHA5782C Patient Care 2
Answer: a. PHA5878C Patient Care 3
41. Which of the following is NOT a first-line agent for fibromyalgia?
- a. Duloxetine
- b. Pregabalin
- c. Amitriptyline
- d. Oxycodone
Answer: d. Oxycodone
42. The most important component of managing chronic pain is:
- a. The specific medication prescribed.
- b. A strong, trusting therapeutic relationship between the patient and the healthcare team.
- c. The use of the newest available technology.
- d. Regular imaging studies.
Answer: b. A strong, trusting therapeutic relationship between the patient and the healthcare team.
43. A pharmacist’s role in chronic pain management includes all of the following EXCEPT:
- a. Assessing for aberrant drug-related behaviors.
- b. Counseling on the risks of long-term opioid use.
- c. Performing interventional pain procedures like nerve blocks.
- d. Recommending non-pharmacologic therapies.
Answer: c. Performing interventional pain procedures like nerve blocks.
44. Urine drug testing in a chronic pain clinic is used to:
- a. Monitor for adherence to prescribed opioids.
- b. Screen for the use of non-prescribed or illicit substances.
- c. Both a and b.
- d. Punish the patient.
Answer: c. Both a and b.
45. Which of the following is a central principle of chronic pain management?
- a. The goal is a quick fix.
- b. The focus is on active patient participation and self-management strategies.
- c. The patient is a passive recipient of care.
- d. Pharmacologic therapy is the only effective treatment.
Answer: b. The focus is on active patient participation and self-management strategies.
46. “Defending a therapeutic plan” for a pain patient is an objective in the skills lab curriculum.
- a. True
- b. False
Answer: a. True
47. The laws regarding the prescribing of controlled substances are a key part of which course?
- a. PHA5703 Principles of Pharmacy Law and Ethics
- b. PHA5244 Principles of Evidence-Based Practice
- c. PHA5104 Sterile Compounding
- d. PHA5176 Drug Delivery Systems
Answer: a. PHA5703 Principles of Pharmacy Law and Ethics
48. An active learning session on pain is part of which course module?
- a. Module 1: Introduction to Pain and Treatment Options
- b. Module 2: Hypertension
- c. Module 4: Ischemic Heart Disease
- d. Module 7: Arrhythmias
Answer: a. Module 1: Introduction to Pain and Treatment Options
49. The overall management of chronic non-cancer pain should prioritize:
- a. Opioid therapy above all other treatments.
- b. Non-opioid and non-pharmacologic therapies.
- c. Surgical interventions.
- d. A “wait and see” approach.
Answer: b. Non-opioid and non-pharmacologic therapies.
50. The ultimate goal of learning about chronic pain management is to:
- a. Be able to safely and compassionately help patients manage their condition to improve their overall quality of life and function.
- b. Become an expert at denying opioid prescriptions.
- c. Pass the final exam.
- d. Memorize all the different types of pain scales.
Answer: a. Be able to safely and compassionately help patients manage their condition to improve their overall quality of life and function.

I am a Registered Pharmacist under the Pharmacy Act, 1948, and the founder of PharmacyFreak.com. I hold a Bachelor of Pharmacy degree from Rungta College of Pharmaceutical Science and Research. With a strong academic foundation and practical knowledge, I am committed to providing accurate, easy-to-understand content to support pharmacy students and professionals. My aim is to make complex pharmaceutical concepts accessible and useful for real-world application.
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