Introduction: A prescription is a legal, written or electronic order from an authorized prescriber to a pharmacist, directing the compounding, dispensing, and labeling of a medicinal product with clear instructions for the patient. B. Pharm students must master the definition and structure of a prescription: superscription (℞), inscription (drug, strength, dosage form), subscription (compounding/quantity to dispense), and signa (directions to the patient). Key skills include interpreting abbreviations, ensuring prescriber and patient identifiers, applying “do-not-use” lists, safe decimal practices, Tall Man lettering, refill and substitution rules, and e-prescription authentication. These competencies improve patient safety, regulatory compliance, and interprofessional communication. Now let’s test your knowledge with 30 MCQs on this topic.
Q1. What is the most accurate definition of a prescription?
- A label affixed to a dispensed medicine
- A verbal counseling session provided by a pharmacist
- A lawful written or electronic order from an authorized prescriber to a pharmacist specifying treatment and directions to the patient
- A drug monograph issued by a regulatory body
Correct Answer: A lawful written or electronic order from an authorized prescriber to a pharmacist specifying treatment and directions to the patient
Q2. In the traditional structure, what does the superscription of a prescription denote?
- Directions to the patient for use
- The symbol ℞ that begins the prescription (“recipe”)
- The list of drug ingredients with their strengths
- Instructions to the pharmacist on compounding
Correct Answer: The symbol ℞ that begins the prescription (“recipe”)
Q3. Which component of a prescription contains the drug name, strength, and dosage form?
- Superscription
- Inscription
- Subscription
- Signa
Correct Answer: Inscription
Q4. The subscription primarily includes which of the following?
- Patient counseling points
- Number of refills authorized
- Instructions to the pharmacist regarding compounding and quantity to dispense
- Prescriber’s diagnosis code
Correct Answer: Instructions to the pharmacist regarding compounding and quantity to dispense
Q5. What does the signa (Sig) represent in a prescription?
- The prescriber’s credentials
- Directions to the patient on how to take the medicine
- The quantity to be compounded
- The prescriber’s registration number
Correct Answer: Directions to the patient on how to take the medicine
Q6. The symbol ℞ on a prescription is derived from Latin and means:
- Write
- Take thou
- Mix
- Label
Correct Answer: Take thou
Q7. Which element is legally essential on most prescriptions?
- Prescriber’s signature (handwritten or authenticated digital signature)
- Patient’s insurance policy number
- Pharmacist’s license number
- Drug cost
Correct Answer: Prescriber’s signature (handwritten or authenticated digital signature)
Q8. Which notation follows safe decimal practices to prevent dosing errors?
- .5 mg and 1.0 mg
- 0.5 mg and 1 mg
- .50 mg and 1.0 mg
- 0.50 mg and 1.00 mg
Correct Answer: 0.5 mg and 1 mg
Q9. Which abbreviation is on the “Do Not Use” list due to risk of misinterpretation?
- mL
- mcg
- U (for units)
- mg
Correct Answer: U (for units)
Q10. The legend “Rx only” on a medicine indicates that it:
- Is available without a prescription
- Is for veterinary use only
- Is a prescription-only medication that requires a prescriber’s authorization
- Is an herbal supplement
Correct Answer: Is a prescription-only medication that requires a prescriber’s authorization
Q11. For pediatric prescriptions, which parameter is most critical for dose calculation?
- Body weight (kg)
- Body temperature (°C)
- Blood group
- Resting heart rate
Correct Answer: Body weight (kg)
Q12. What does “DAW” indicate when written on a prescription?
- Dispense after warning
- Dispense as written (no substitution)
- Deliver at ward
- Dose as warranted
Correct Answer: Dispense as written (no substitution)
Q13. A key advantage of e-prescriptions over handwritten prescriptions is:
- They eliminate the need for counseling
- They reduce errors due to illegible handwriting and enable decision support
- They remove the requirement for a prescriber’s signature
- They allow unlimited refills
Correct Answer: They reduce errors due to illegible handwriting and enable decision support
Q14. Which feature best authenticates an e-prescription for controlled medicines?
- Use of colored fonts
- Two-factor authenticated digital signature
- All caps text
- Inclusion of drug brand logo
Correct Answer: Two-factor authenticated digital signature
Q15. The “refill authorization” on a prescription communicates:
- The compounding instructions
- The number of times the medicine may be dispensed again without a new prescription
- The price cap for the medicine
- The patient’s copayment amount
Correct Answer: The number of times the medicine may be dispensed again without a new prescription
Q16. In prescription directions, the abbreviation “PRN” means:
- Before meals
- At bedtime
- As needed
- Every hour
Correct Answer: As needed
Q17. The abbreviation “q.i.d.” in a Sig most correctly means:
- Four times daily
- Every other day
- Once daily
- Every six hours as needed
Correct Answer: Four times daily
Q18. Which Sig is the most patient-friendly and clear?
- 1 tab po qid
- Take one tablet by mouth four times daily
- 1 t po 4x/d
- Tab 1 oral qid pc
Correct Answer: Take one tablet by mouth four times daily
Q19. In prescription terminology, “SL” indicates administration:
- Subcutaneous
- Sublingual
- Supra-labial
- Slow-release
Correct Answer: Sublingual
Q20. Which of the following is NOT typically required on a valid prescription?
- Prescriber’s signature
- Date of issuance
- Patient’s identifiers
- Pharmacist’s license number
Correct Answer: Pharmacist’s license number
Q21. Tall Man lettering (e.g., “hydrOXYzine” vs “hydrALAZINE”) is used to:
- Indicate brand-name drugs
- Highlight controlled substances
- Reduce look-alike/sound-alike medication errors
- Mark pediatric doses
Correct Answer: Reduce look-alike/sound-alike medication errors
Q22. Which of the following Sigs is complete and clear for labeling?
- 1 cap twice
- Take one capsule twice daily
- One twice daily for infection
- 1 cap by mouth after meals
Correct Answer: Take one capsule twice daily
Q23. Which notation is safest to express microgram doses in a prescription?
- µg
- mcg
- ug
- mg
Correct Answer: mcg
Q24. The Latin instruction “Misce, fiat unguentum” in the subscription directs the pharmacist to:
- Prepare a syrup
- Prepare an ointment
- Prepare a suppository
- Prepare a capsule
Correct Answer: Prepare an ointment
Q25. The reference that lists therapeutic equivalence codes (e.g., AB) to support generic substitution is the:
- Red Book (pricing)
- British Pharmacopoeia
- FDA Orange Book
- Martindale
Correct Answer: FDA Orange Book
Q26. Which is a common red flag suggesting a possibly forged prescription?
- Erasures or overwriting on the quantity
- Clear, typed e-prescription
- Valid patient ID presented
- Prescription dated today
Correct Answer: Erasures or overwriting on the quantity
Q27. Choose the correct traditional sequence of prescription parts:
- Inscription → Superscription → Signa → Subscription
- Superscription → Inscription → Subscription → Signa
- Signa → Subscription → Superscription → Inscription
- Subscription → Inscription → Signa → Superscription
Correct Answer: Superscription → Inscription → Subscription → Signa
Q28. The primary legal purpose of a prescription is to:
- Advertise a drug’s benefits
- Authorize the dispensing of a medication to a specific patient under a prescriber’s direction
- Replace the need for patient consent
- Document manufacturer quality
Correct Answer: Authorize the dispensing of a medication to a specific patient under a prescriber’s direction
Q29. Which component is primarily intended for the pharmacist rather than the patient?
- Signa
- Subscription
- Patient counseling notes
- Refill authorization
Correct Answer: Subscription
Q30. Which element in the Sig most helps ensure appropriate cessation of therapy?
- Brand preference
- Route of administration
- Duration of therapy
- Prescriber’s specialty
Correct Answer: Duration of therapy

I am a Registered Pharmacist under the Pharmacy Act, 1948, and the founder of PharmacyFreak.com. I hold a Bachelor of Pharmacy degree from Rungta College of Pharmaceutical Science and Research. With a strong academic foundation and practical knowledge, I am committed to providing accurate, easy-to-understand content to support pharmacy students and professionals. My aim is to make complex pharmaceutical concepts accessible and useful for real-world application.
Mail- Sachin@pharmacyfreak.com

