Universal Immunization Programme (UIP) MCQs With Answer

Universal Immunization Programme (UIP) MCQs With Answer is a focused resource for B. Pharm students covering India’s flagship immunization strategy. This introduction outlines core concepts: vaccines in the UIP schedule, cold chain management, vaccine-preventable diseases, adverse events following immunization (AEFI), surveillance, program implementation and monitoring, and key initiatives like Mission Indradhanush. Emphasis on technical details — vaccine types, storage temperatures, vial monitoring, session planning, and pharmacovigilance — prepares pharmacy students for clinical, logistical, and regulatory roles. Familiarity with UIP strengthens understanding of public health immunization policy, vaccine safety, and supply-chain challenges. Now let’s test your knowledge with 30 MCQs on this topic.

Q1. What is the primary objective of the Universal Immunization Programme (UIP) in India?

• To provide free medicines for all chronic diseases
• To eliminate all infectious diseases within five years
• To reduce morbidity and mortality from vaccine-preventable diseases
• To export vaccines to other countries

Correct Answer: To reduce morbidity and mortality from vaccine-preventable diseases

Q2. Which of the following vaccines is included in the UIP birth dose?

• Measles–Rubella vaccine
• Hepatitis B vaccine
• Oral Polio Vaccine (OPV) first dose at 6 weeks
• Rotavirus vaccine

Correct Answer: Hepatitis B vaccine

Q3. What is the recommended storage temperature range for most routine vaccines under UIP?

• -20°C to -10°C
• 2°C to 8°C
• 15°C to 25°C
• Below -70°C

Correct Answer: 2°C to 8°C

Q4. Vaccine Vial Monitor (VVM) is used to monitor which parameter?

• Exposure to freezing temperatures
• Accumulated heat exposure
• Sterility breach of vial
• pH changes in vaccine

Correct Answer: Accumulated heat exposure

Q5. Which adjuvant is most commonly used in UIP vaccines to enhance immune response?

• Aluminium salts (alum)
• Monophosphoryl lipid A (MPL)
• Squalene (MF59)
• Complete Freund’s adjuvant

Correct Answer: Aluminium salts (alum)

Q6. The UIP session type conducted at fixed health facilities on predetermined days is called:

• Outreach Session
• Special Immunization Drive
• Fixed Session
• Mass Vaccination Campaign

Correct Answer: Fixed Session

Q7. Which vaccine in UIP is administered orally?

• Inactivated poliovirus vaccine (IPV)
• Oral Polio Vaccine (OPV)
• BCG vaccine
• Pentavalent vaccine

Correct Answer: Oral Polio Vaccine (OPV)

Q8. Which component is NOT part of the cold chain equipment used in UIP?

• Ice-lined refrigerator (ILR)
• Vaccine carrier
• Deep freezers for ultra-cold storage (-150°C)
• Cold box

Correct Answer: Deep freezers for ultra-cold storage (-150°C)

Q9. AEFI stands for:

• Adverse Events Following Immunization
• Age-Exempted For Immunization
• Automated Evaluation of Fertility Index
• Annual Evaluation For Immunity

Correct Answer: Adverse Events Following Immunization

Q10. Which UIP vaccine provides protection against tuberculosis?

• BCG
• Hepatitis B
• Measles–Rubella
• Pneumococcal conjugate vaccine (PCV)

Correct Answer: BCG

Q11. Which vaccine in the UIP is given to adolescents (girls) under school-based HPV program?

• Hepatitis B vaccine
• Human Papillomavirus (HPV) vaccine
• Rotavirus vaccine
• Japanese Encephalitis vaccine

Correct Answer: Human Papillomavirus (HPV) vaccine

Q12. Mission Indradhanush primarily aims to:

• Introduce new vaccines into UIP
• Improve vaccination coverage in underserved areas
• Replace oral vaccines with injectable vaccines
• Provide vitamin supplementation

Correct Answer: Improve vaccination coverage in underserved areas

Q13. Which indicator is commonly used to assess UIP immunization performance?

• Incidence of influenza per 1000
• Percentage coverage of fully immunized children
• Number of vaccine manufacturers
• Annual healthcare expenditure per capita

Correct Answer: Percentage coverage of fully immunized children

Q14. The pentavalent vaccine in UIP combines protection against which diseases?

• Diphtheria, Tetanus, Pertussis, Polio, Measles
• Hepatitis B, Haemophilus influenzae type b, DPT
• BCG, Hepatitis B, Measles, Rubella, JE
• Pneumococcus, Rotavirus, HPV, JE, HepA

Correct Answer: Hepatitis B, Haemophilus influenzae type b, DPT

Q15. What is the multi-dose vial policy (MDVP) primarily designed to address?

• Wastage due to single-dose vials
• Safe reuse of needles
• Use of opened multi-dose vials for subsequent sessions when conditions permit
• Extending vaccine shelf-life beyond manufacturer expiry

Correct Answer: Use of opened multi-dose vials for subsequent sessions when conditions permit

Q16. Which of the following is a heat-sensitive vaccine indicator that changes color irreversibly when exposed to cumulative heat?

• Vaccine Vial Monitor (VVM)
• Thermometer mercury column
• Cold chain alarm
• pH paper strip

Correct Answer: Vaccine Vial Monitor (VVM)

Q17. Which vaccine is contraindicated in severely immunocompromised individuals under UIP?

• Inactivated polio vaccine (IPV)
• Live attenuated measles-containing vaccine
• Hepatitis B vaccine
• Tetanus toxoid

Correct Answer: Live attenuated measles-containing vaccine

Q18. Which organization provides technical support and policy guidance to UIP at international level?

• World Health Organization (WHO)
• World Trade Organization (WTO)
• International Monetary Fund (IMF)
• Federation Internationale de Football Association (FIFA)

Correct Answer: World Health Organization (WHO)

Q19. An AEFI that is severe, unexpected, and possibly related to immunization should be reported to:

• Local hospital billing department
• AEFI surveillance and reporting system at district/state level
• Pharmacy inventory manager
• Vaccine manufacturer only

Correct Answer: AEFI surveillance and reporting system at district/state level

Q20. Which UIP vaccine helps prevent diarrheal hospitalizations due to rotavirus?

• Rotavirus vaccine
• Measles–Rubella vaccine
• Pneumococcal conjugate vaccine (PCV)
• BCG vaccine

Correct Answer: Rotavirus vaccine

Q21. Which cold chain equipment is used to transport vaccines to outreach sessions for short durations?

• Ice-lined refrigerator (ILR)
• Deep freezer
• Vaccine carrier
• Ultra-low temperature freezer

Correct Answer: Vaccine carrier

Q22. Which of the following is a core surveillance activity under UIP for monitoring vaccine-preventable diseases?

• Adverse drug reaction monitoring for antibiotics
• Acute flaccid paralysis (AFP) surveillance for polio
• Monthly pharmacy stock audit
• Annual influenza serosurvey only

Correct Answer: Acute flaccid paralysis (AFP) surveillance for polio

Q23. Which parameter is NOT typically recorded on an immunization card in UIP?

• Date of vaccination
• Vaccine batch number
• Child’s birth weight at delivery
• Name of vaccine administered

Correct Answer: Child’s birth weight at delivery

Q24. The introduction of Injectable Polio Vaccine (IPV) into UIP was primarily to:

• Replace all oral vaccines immediately
• Provide additional protection and reduce vaccine-derived poliovirus risk
• Increase cold chain complexity without benefit
• Be used only in outbreak settings

Correct Answer: Provide additional protection and reduce vaccine-derived poliovirus risk

Q25. Which waste disposal method is recommended in UIP for used syringes and needles?

• Open burning in community areas
• Sharps disposal in puncture-proof containers followed by incineration or deep burial as per guidelines
• Reuse after boiling
• Dispose in regular household garbage

Correct Answer: Sharps disposal in puncture-proof containers followed by incineration or deep burial as per guidelines

Q26. Which vaccine in the UIP contains an inactivated (killed) virus?

• BCG
• Inactivated Polio Vaccine (IPV)
• Measles vaccine
• Oral Polio Vaccine (OPV)

Correct Answer: Inactivated Polio Vaccine (IPV)

Q27. Which documentation is critical for vaccine lot traceability in UIP?

• Vaccine Lot Number and Expiry recorded at point of administration
• Only donor name for batch
• Cold chain equipment serial number only
• Manufacturer invoice without batch details

Correct Answer: Vaccine Lot Number and Expiry recorded at point of administration

Q28. Which of the following best describes a “fully immunized child” as per UIP definitions?

• Child who has received BCG, measles only
• Child who received all UIP recommended vaccines appropriate for age by 12–23 months
• Child who received at least one vaccine dose
• Child vaccinated only during campaigns

Correct Answer: Child who received all UIP recommended vaccines appropriate for age by 12–23 months

Q29. Which of the following is a vaccine-preventable disease targeted by UIP elimination goals?

• Poliomyelitis
• Type 2 diabetes
• Hypertension
• Common cold exclusively

Correct Answer: Poliomyelitis

Q30. Which component of UIP ensures quality of immunization through training, supervision and monitoring?

• Pharmaceutical sales representatives
• Human resource development and capacity building
• Only vaccine procurement
• Advertising campaigns

Correct Answer: Human resource development and capacity building

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