Lymphadenopathy MCQ Quiz | Head & Neck

1. Which level of cervical lymph nodes is also known as the jugulodigastric group, often enlarged in tonsillitis?

2. Virchow’s node, a left supraclavicular node, is classically associated with metastasis from which primary site?

3. The submental lymph nodes (Level IA) primarily drain which of the following structures?

4. A patient presents with multiple, matted, caseating cervical lymph nodes, a condition known as scrofula. What is the most likely causative organism?

5. Which group of lymph nodes forms the “main final common pathway” for lymph from the entire head and neck?

6. A “shotty” lymphadenopathy, characterized by small, mobile, non-tender nodes, is most commonly associated with:

7. The posterior cervical lymph nodes (Level V) are located in which anatomical triangle?

8. Waldeyer’s ring of lymphoid tissue includes all of the following EXCEPT:

9. In the context of head and neck squamous cell carcinoma, what is the most important prognostic factor?

10. The jugulo-omohyoid lymph node is an important landmark found at the junction of the internal jugular vein and the omohyoid muscle. It belongs to which level?

11. A young adult presents with fever, pharyngitis, and posterior cervical lymphadenopathy. A blood smear shows atypical lymphocytes. What is the most likely diagnosis?

12. Which imaging modality is considered the first-line investigation for evaluating cervical lymphadenopathy?

13. A fixed, hard, and non-tender lymph node in an elderly patient is highly suspicious for:

14. The pre-auricular lymph nodes primarily drain which of the following areas?

15. Which level of cervical lymph nodes is located in the anterior compartment, between the carotid arteries, from the hyoid bone to the suprasternal notch?

16. Fine Needle Aspiration Cytology (FNAC) is a common procedure for lymphadenopathy. What is its primary purpose?

17. A “sentinel lymph node biopsy” is a procedure designed to:

18. Lymphatic drainage from the nasopharynx primarily goes to which nodes?

19. Which of the following is NOT a characteristic feature of a malignant lymph node on ultrasound?

20. Hodgkin’s lymphoma is a malignancy of the lymphatic system. The characteristic diagnostic cell found on biopsy is the:

21. The Delphian node is a pre-laryngeal lymph node located in the midline. Its enlargement is often associated with cancer of the:

22. Which levels of the cervical lymph nodes are primarily involved in drainage from the oral cavity?

23. The submandibular lymph nodes (Level IB) receive lymphatic drainage from all the following structures EXCEPT:

24. In Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis), which group of lymph nodes is most commonly affected?

25. A patient is diagnosed with squamous cell carcinoma of the floor of the mouth. What is the most likely initial site of nodal metastasis?