Benign & Malignant Disorders MCQ Quiz | Hypopharynx

Welcome, MBBS students, to this specialized multiple-choice quiz on the Benign and Malignant Disorders of the Hypopharynx. This quiz is designed to test your understanding of the anatomy, epidemiology, clinical presentation, diagnosis, and management principles related to conditions affecting this complex region. You will encounter 25 questions covering key topics such as squamous cell carcinoma, risk factors like Plummer-Vinson syndrome, staging, and treatment modalities. This assessment will help you consolidate your knowledge for both theoretical exams and clinical practice. After submitting your answers, you will receive your score and see the correct answers highlighted. For your revision, you can also download a PDF document containing all the questions along with their correct answers. Good luck!

1. Which is the most common subsite for hypopharyngeal carcinoma?

2. The triad of dysphagia, iron-deficiency anemia, and esophageal webs is characteristic of which syndrome, a known risk factor for postcricoid carcinoma?

3. The most common histological type of malignant tumor in the hypopharynx is:

4. Referred otalgia in a patient with a hypopharyngeal mass is typically mediated by the auricular branch of which cranial nerve?

5. According to the AJCC 8th edition staging, a hypopharyngeal tumor that invades the larynx and causes vocal cord fixation is classified as:

6. The “Sign of Trotter,” which is ipsilateral eustachian tube dysfunction and middle ear effusion, is most commonly associated with tumors of the:

7. Which of the following is the most significant prognostic factor in hypopharyngeal carcinoma?

8. A benign, pedunculated fibrovascular polyp is most likely to arise from which part of the hypopharynx/upper esophagus?

9. The primary lymphatic drainage of the pyriform sinus is to which nodal levels?

10. What is the standard of care for a small (T1) hypopharyngeal carcinoma with no nodal involvement (N0)?

11. A “hot potato” or muffled voice is a classic symptom more commonly associated with pathology of the:

12. The most common benign tumor of the hypopharynx is:

13. In staging hypopharyngeal cancer, involvement of the prevertebral fascia makes the tumor:

14. Which investigation is essential for obtaining a definitive histopathological diagnosis of a hypopharyngeal lesion?

15. The concept of “field cancerization” in head and neck cancers, including the hypopharynx, implies an increased risk of:

16. Reconstruction after a total laryngopharyngectomy is most commonly performed using a:

17. Which of the following is NOT a recognized subsite of the hypopharynx?

18. A patient presents with progressive dysphagia and a palpable neck mass. This clinical picture in hypopharyngeal cancer often indicates:

19. The superior border of the hypopharynx is at the level of the:

20. Which of these chemotherapy agents is a cornerstone in the treatment of advanced hypopharyngeal SCC?

21. In a patient with postcricoid carcinoma, hoarseness is most likely caused by tumor invasion of the:

22. What is the main goal of larynx preservation protocols in treating hypopharyngeal cancer?

23. A Zenker’s diverticulum, a benign pulsion diverticulum, arises from a defect in which muscle?

24. What is the most common site for distant metastasis from hypopharyngeal carcinoma?

25. A laryngocele is an abnormal air-filled dilatation of which part of the larynx, which can present as a neck mass and mimic a hypopharyngeal cyst?

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