Investigations in Pregnancy MCQ Quiz | Obstetrics

Welcome to the Investigations in Pregnancy quiz. This assessment is designed for MBBS students to test their knowledge on the essential antenatal screening and diagnostic procedures in obstetrics. The quiz covers a range of topics including routine blood tests, screening for chromosomal abnormalities like the Double and Quadruple tests, Non-Invasive Prenatal Testing (NIPT), and diagnostic procedures such as amniocentesis and CVS. It also evaluates your understanding of fetal surveillance methods like the Non-Stress Test (NST), Biophysical Profile (BPP), and Doppler ultrasonography. This comprehensive quiz will help you consolidate key concepts and prepare for your examinations. After submitting your answers, you can review your score and download a PDF of all questions with the correct answers for future revision.

1. First-trimester screening for aneuploidy (Double test) measures which two maternal serum markers?

2. When is the optimal time to perform an anomaly scan (TIFFA/Level II scan)?

3. The ‘triple test’ for aneuploidy screening, performed in the second trimester, includes which markers?

4. A Non-Stress Test (NST) is considered ‘reactive’ if it shows:

5. Chorionic Villus Sampling (CVS) is typically performed at what gestational age?

6. What is the primary purpose of a Doppler ultrasound of the umbilical artery in the third trimester?

7. A 75g Oral Glucose Tolerance Test (OGTT) is performed to screen for what condition in pregnancy?

8. Nuchal Translucency (NT) measurement via ultrasound is a key component of which screening test?

9. Which investigation is considered the gold standard for diagnosing fetal chromosomal abnormalities?

10. In an Rh-negative mother without sensitization, when is Anti-D immunoglobulin typically administered prophylactically?

11. A Biophysical Profile (BPP) score of 4/10 indicates what?

12. The Quadruple test adds which marker to the Triple test for improved Down syndrome screening?

13. Non-invasive prenatal testing (NIPT) analyzes what from the maternal blood?

14. Which of the following is a routine investigation in the first antenatal visit for all pregnant women?

15. Amniocentesis for genetic diagnosis is generally performed between which weeks of gestation?

16. Elevated maternal serum alpha-fetoprotein (MSAFP) is most strongly associated with which fetal anomaly?

17. A ‘dating scan’ in the first trimester is most accurate for determining the estimated date of delivery (EDD) based on which measurement?

18. In a patient with suspected pre-eclampsia, which of the following laboratory findings would be most indicative?

19. A microscopic examination of vaginal fluid showing a ‘ferning’ pattern confirms what?

20. A contraction stress test (CST) is considered positive (abnormal) if:

21. What is the primary risk associated with invasive diagnostic procedures like amniocentesis and CVS?

22. A fetal fibronectin (fFN) test performed on cervicovaginal secretions is used to predict the risk of:

23. In universal screening for Group B Streptococcus (GBS) at 36-38 weeks, where is the swab sample collected from?

24. Low levels of Pregnancy-Associated Plasma Protein-A (PAPP-A) in the first trimester are associated with an increased risk of:

25. Which component of the biophysical profile (BPP) is considered an indicator of chronic (long-term) fetal hypoxia if abnormal?