Immune Response & Infection Basics MCQ Quiz | Infectious Diseases – General

Welcome to this specialized quiz for MBBS students, focusing on the fundamental principles of Immune Response and Infection Basics. This assessment is designed to test your understanding of the intricate interplay between the host’s immune system and invading pathogens. The quiz covers essential topics including innate and adaptive immunity, the roles of various immune cells, cytokine function, the complement system, hypersensitivity reactions, and the core concepts of infectious processes. This self-assessment tool will help you reinforce your knowledge and identify areas for further study. After completing the 25 questions, you can submit your answers to see your score and review the correct responses. You will also have the option to download all questions with their correct answers in a PDF format for offline revision.

1. Which of the following is a key feature of the adaptive immune system but not the innate immune system?

2. The primary phagocytic cell type that responds first during an acute bacterial infection is:

3. Which cell type is considered the most potent antigen-presenting cell (APC) for activating naive T lymphocytes?

4. The immunoglobulin class predominantly involved in type I hypersensitivity reactions is:

5. Major Histocompatibility Complex (MHC) class I molecules present processed antigens primarily to:

6. The first immunoglobulin class to be produced during a primary immune response is:

7. Which of the following cytokines is a key mediator of the acute phase response and is a potent endogenous pyrogen?

8. The classical pathway of the complement system is typically initiated by:

9. A delayed-type hypersensitivity reaction, such as the tuberculin skin test, is mediated by:

10. The term “virulence” in microbiology refers to:

11. An opportunistic pathogen is best defined as an organism that:

12. Which of the following is NOT one of the four cardinal signs of inflammation described by Celsus?

13. The primary role of CD4+ T helper cells is to:

14. Vaccination primarily aims to induce what type of immunity?

15. Pattern Recognition Receptors (PRRs) such as Toll-like receptors (TLRs) recognize:

16. The most abundant immunoglobulin class found in human serum is:

17. Opsonization, the process of coating a pathogen to enhance phagocytosis, is a major function of:

18. Natural Killer (NK) cells are a component of the innate immune system that primarily targets:

19. Which of the following best describes the anamnestic (secondary) immune response compared to the primary response?

20. The final step of the complement cascade, which directly damages pathogen membranes, is the formation of:

21. Humoral immunity is most effective against which type of pathogen?

22. An infant receiving antibodies from its mother’s milk is an example of:

23. Type III hypersensitivity reactions (e.g., serum sickness) are caused by:

24. Severe Combined Immunodeficiency (SCID) is a primary immunodeficiency characterized by a severe defect in:

25. A bacterial capsule is a virulence factor primarily because it: