Cancers (Common) MCQ Quiz | Non-Communicable Diseases

Welcome to the Common Cancers MCQ Quiz, specifically designed for MBBS students studying Non-Communicable Diseases. This quiz will test your understanding of the epidemiology, risk factors, screening, diagnosis, and key clinical features of prevalent malignancies. You will face 25 challenging multiple-choice questions covering topics from breast and lung cancer to colorectal and cervical cancers. This assessment serves as an excellent tool for self-evaluation and revision before your examinations. After completing the quiz, you can submit your answers to see your score and review the correct responses. For your convenience, a button will be available to download all the questions along with their correct answers in a PDF format for offline study. Good luck!

1. Which of the following pairs of Human Papillomavirus (HPV) types are most commonly associated with the development of cervical cancer?

2. Germline mutations in which of the following genes confer the highest lifetime risk for developing hereditary breast and ovarian cancer?

3. What is the most common histological subtype of lung cancer found in non-smokers?

4. Carcinoembryonic antigen (CEA) is a tumor marker most commonly used for monitoring the recurrence of which cancer?

5. The Gleason scoring system is used for grading the aggressiveness of which type of cancer?

6. Chronic infection with which of the following microorganisms is the strongest known risk factor for gastric adenocarcinoma?

7. What is the most common primary malignant tumor of the liver worldwide?

8. A Papanicolaou (Pap) smear is a screening test used for the early detection of:

9. Which molecular subtype of breast cancer is associated with the poorest prognosis due to lack of targeted therapy options?

10. The Syndrome of Inappropriate Antidiuretic Hormone (SIADH) secretion is a well-known paraneoplastic syndrome associated with which type of lung cancer?

11. The vast majority of colorectal cancers develop from which precursor lesion?

12. In the TNM staging system for cancer, what does ‘M1’ signify?

13. Which of the following is the most common type of skin cancer?

14. The presence of ‘signet ring’ cells on histology is a classic feature of which type of gastric cancer?

15. Chronic gastroesophageal reflux disease (GERD) is a major risk factor for which type of esophageal cancer?

16. Mammography is the standard screening modality for which cancer in asymptomatic women over the age of 40-50?

17. An elevated serum CA-125 level is most commonly associated with which gynecological malignancy?

18. A patient presenting with painless jaundice, weight loss, and a palpable, non-tender gallbladder (Courvoisier’s sign) is highly suspicious for cancer of the:

19. Which is the most common and least aggressive histological type of thyroid cancer?

20. Occupational exposure to aniline dyes is a significant risk factor for which type of cancer?

21. The Philadelphia chromosome, a translocation t(9;22), is a pathognomonic finding in which hematological malignancy?

22. The presence of Reed-Sternberg cells on lymph node biopsy is diagnostic for:

23. What is the most common primary malignant brain tumor in adults?

24. Lynch syndrome (HNPCC) is an autosomal dominant genetic condition that increases the risk of many types of cancer, most notably:

25. Prostate-Specific Antigen (PSA) is a widely used serum marker for the screening and monitoring of: