Leprosy MCQ Quiz | Communicable Diseases

Welcome to the Leprosy (Hansen’s Disease) quiz, specifically designed for MBBS students. This quiz will test your understanding of the key aspects of leprosy, a chronic infectious disease caused by Mycobacterium leprae. The 25 multiple-choice questions cover its etiology, classification, clinical manifestations, diagnostic methods, multi-drug therapy (MDT), and management of lepra reactions. This assessment is a valuable tool for self-evaluation and revision for your examinations. After submitting your answers, you will receive your score and a detailed review of each question, highlighting the correct and incorrect responses. You can also download a PDF copy of all questions and their correct answers for future reference. Good luck!

1. What is the causative agent of Leprosy?

2. The primary mode of transmission for Mycobacterium leprae is believed to be:

3. Which classification system is used to describe the spectrum of leprosy based on immunological response?

4. A patient with Tuberculoid (TT) leprosy typically exhibits:

5. Which of the following is NOT a cardinal sign for the diagnosis of leprosy?

6. A Type 1 Lepra Reaction (Reversal Reaction) is a manifestation of:

7. Erythema Nodosum Leprosum (ENL) is characteristic of which form of leprosy?

8. The standard WHO Multi-Drug Therapy (MDT) for Multibacillary (MB) leprosy in adults consists of:

9. What is the recommended duration of MDT for Paucibacillary (PB) leprosy?

10. Which peripheral nerve is most commonly affected in leprosy, leading to a claw hand deformity?

11. A slit-skin smear is used to calculate the Bacteriological Index (BI). What does a BI of 6+ indicate?

12. The histopathological hallmark of Lepromatous Leprosy (LL) is the presence of:

13. Which drug in the MDT regimen is known to cause a reddish-orange discoloration of urine and other body fluids?

14. What is the average incubation period of leprosy?

15. A patient on MDT for leprosy develops reddish-brown skin discoloration and ichthyosis. Which drug is most likely responsible?

16. The “Leonine Facies” is a classical clinical finding in which type of leprosy?

17. Damage to the common peroneal nerve in leprosy typically results in:

18. The WHO classification of leprosy into Paucibacillary (PB) and Multibacillary (MB) is primarily based on:

19. In the context of leprosy, what is Lucio’s phenomenon?

20. The primary drug for managing a severe Type 1 Lepra Reaction (Reversal Reaction) is:

21. While corticosteroids are first-line for ENL, which drug is highly effective for chronic or recurrent ENL, especially in non-pregnant patients?

22. What is the main purpose of the Lepromin (Mitsuda) test?

23. Lagophthalmos in a leprosy patient is a result of damage to which cranial nerve?

24. What is the primary mechanism of action of Dapsone?

25. A patient is considered “released from treatment” (RFT) after completing MDT. What is the most important component of follow-up for these patients?