Bacterial Viral Parasitic & Fungal Zoonoses MCQ Quiz | Zoonoses

1. Negri bodies are characteristic intracytoplasmic inclusions found in which viral zoonosis?

2. A 45-year-old farmer presents with a painless, black, necrotic eschar on his forearm. He reports handling goat hides recently. What is the most likely causative agent?

3. Undulant fever, characterized by rising and falling fever, night sweats, and arthralgia, is a hallmark of which zoonotic infection, often associated with unpasteurized dairy products?

4. A sanitation worker presents with high fever, myalgia, conjunctival suffusion, and jaundice. He has a history of working in water-logged areas. Weil’s disease is the severe form of which spirochetal zoonosis?

5. A pregnant woman is advised to avoid cleaning cat litter boxes to prevent congenital infection with which parasite?

6. Bubonic plague, caused by *Yersinia pestis*, is primarily transmitted to humans by which vector?

7. A patient from a sheep-rearing community is found to have a large, unilocular cystic lesion in the liver on ultrasound. Serology is positive for antibodies against which parasite?

8. Which subtype of Influenza A virus is of major concern for its potential to cause pandemics through zoonotic transmission from birds to humans?

9. An abattoir worker develops an atypical pneumonia, high fever, and severe headache. This presentation is classic for an infection with *Coxiella burnetii*, also known as:

10. Neurocysticercosis, a major cause of adult-onset seizures in developing countries, results from the ingestion of eggs from which tapeworm?

11. Kyasanur Forest Disease, a viral hemorrhagic fever prevalent in parts of Karnataka, India, is transmitted by the bite of:

12. Kala-azar (visceral leishmaniasis), characterized by hepatosplenomegaly, fever, and pancytopenia, is transmitted by the bite of an infected:

13. A cave explorer from the Ohio River Valley presents with fever, cough, and chest X-ray findings of pulmonary infiltrates and hilar lymphadenopathy. The most likely fungal zoonosis, associated with bird and bat droppings, is:

14. A hunter develops an ulcer at the site of a tick bite, accompanied by high fever and painful regional lymphadenopathy. This clinical form (ulceroglandular) is most characteristic of:

15. Hantavirus Pulmonary Syndrome (HPS) is a severe respiratory illness transmitted to humans primarily through:

16. The primary amplifying host for Japanese Encephalitis virus, a major cause of viral encephalitis in Asia, is:

17. An immunocompromised patient (e.g., with AIDS) presents with meningitis. An India ink stain of the CSF reveals encapsulated yeast forms. This presentation is highly suggestive of which fungal infection, often associated with pigeon droppings?

18. Non-typhoidal *Salmonella* infection in humans is most commonly acquired through:

19. A patient presents with periorbital edema, myalgia, and high eosinophilia after consuming undercooked pork from a wild boar. This is a classic presentation of:

20. According to WHO guidelines for post-exposure prophylaxis (PEP) for a Category III bite from a suspected rabid animal, what is the immediate and correct course of action?

21. Erythema migrans, a characteristic “bull’s-eye” rash, is the hallmark sign of the early localized stage of which tick-borne bacterial zoonosis?

22. A pet shop owner presents with fever, a dry cough, and interstitial pneumonia. He recently received a shipment of imported parrots. The most likely causative agent is:

23. Rift Valley Fever, a viral zoonosis primarily affecting livestock and humans in Africa, is mainly transmitted by:

24. Visceral Larva Migrans (VLM) and Ocular Larva Migrans (OLM) are clinical syndromes caused by the migration of larvae of which roundworm, commonly found in dogs and cats?

25. The most critical public health measure to prevent human cystic echinococcosis (hydatid disease) is: