Neurotransmitters MCQ Quiz | Neurophysiology

Welcome to the Neurotransmitters Quiz for MBBS students. This quiz is designed to test your understanding of the fundamental concepts of neurophysiology, focusing on the synthesis, release, action, and clinical relevance of various neurotransmitters. You will be presented with 25 multiple-choice questions covering key topics such as catecholamines, acetylcholine, amino acid transmitters, and neuropeptides. After submitting your answers, your score will be displayed, and each question will be marked to show the correct and incorrect responses. You can also download a PDF copy of all the questions with their correct answers for your revision. This is an excellent tool to consolidate your knowledge and prepare for your examinations. Good luck!

1. A deficiency in which neurotransmitter is primarily associated with the motor symptoms of Parkinson’s disease?

2. The action of acetylcholine in the synaptic cleft is terminated primarily by:

3. Which of the following is the principal excitatory neurotransmitter in the mammalian central nervous system?

4. GABAergic inhibition is typically mediated by the influx of which ion into the postsynaptic neuron?

5. Norepinephrine, epinephrine, and dopamine belong to which class of neurotransmitters?

6. Serotonin (5-Hydroxytryptamine) is synthesized from which essential amino acid?

7. NMDA, AMPA, and Kainate receptors are ionotropic receptors for which neurotransmitter?

8. Myasthenia gravis is an autoimmune disease characterized by antibodies against which receptors at the neuromuscular junction?

9. Metabotropic receptors exert their effects through:

10. Which of the following is an inhibitory neurotransmitter primarily found in the spinal cord and brainstem?

11. Nitric oxide (NO) is considered an unconventional neurotransmitter because it:

12. The analgesic effects of morphine are mediated by its action as an agonist at receptors for which endogenous neurotransmitters?

13. Selective Serotonin Reuptake Inhibitors (SSRIs) primarily treat depression by:

14. The synthesis of all catecholamines begins with the amino acid:

15. A substance that binds to a receptor but does not activate it, thereby preventing the neurotransmitter from binding, is known as a(n):

16. The majority of serotonin-producing neurons in the CNS are located in the:

17. The primary mechanism of action for typical antipsychotic drugs used to treat schizophrenia involves blockade of which receptors?

18. The neurotransmitter released by motor neurons at the skeletal neuromuscular junction is:

19. Botulinum toxin induces muscle paralysis by:

20. The neuropeptide Substance P is a key mediator in the transmission of:

21. The rate-limiting enzyme in the synthesis of catecholamines is:

22. Benzodiazepines, such as diazepam, exert their anxiolytic and sedative effects by enhancing the action of GABA at which receptor subtype?

23. Which of the following is considered a retrograde neurotransmitter, often synthesized in the postsynaptic neuron to act on the presynaptic terminal?

24. Histamine as a neurotransmitter in the CNS is primarily involved in:

25. Dale’s principle states that a neuron: